PMID: Aging (Albany NY). 2019 Jul 13 ;11(13):4706-4719. PMID: 31301169 Abstract Title: Tea polyphenol protects against cisplatin-induced meiotic defects in porcine oocytes. Abstract: DDP (cisplatin), a DNA cross-linking agent, is one of the most common chemotherapeutic drugs that have been widely used in the treatment of sarcomas and germ cell tumors. DDP treatment exhibits severe …
Author Archives: Taylor Mercado
Melatonin and (-)-epigallocatechin-3-gallate: Partners in fighting cancer.
PMID: Cells. 2019 Jul 19 ;8(7). Epub 2019 Jul 19. PMID: 31331008 Abstract Title: Melatonin and (-)-Epigallocatechin-3-Gallate: Partners in Fighting Cancer. Abstract: We have demonstrated previously that melatonin attenuates hepatotoxicity triggered by high doses of (-)-epigallocatechin-3-gallate (EGCG) in mice. The current work investigated the influence of melatonin on the oncostatic activity of EGCG in two …
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Epigallocatechin gallate suppresses epithelial-mesenchymal transition and invasion in anaplastic thyroid carcinoma cells.
PMID: Bioengineered. 2019 Dec ;10(1):282-291. PMID: 31311401 Abstract Title: Epigallocatechin gallate (EGCG) suppresses epithelial-Mesenchymal transition (EMT) and invasion in anaplastic thyroid carcinoma cells through blocking of TGF-β1/Smad signaling pathways. Abstract: Transforming growth factor (TGF)-β1 plays a crucial role in the epithelial-to-mesenchymal transition (EMT) in many cancer types and in thyroid cancers. Epigallocatechin-3-gallate (EGCG), the most …
Usage of and attitudes about green tea extract and epigallocathechin-3-gallate as a therapy in individuals with Down syndrome.
PMID: Complement Ther Med. 2019 Aug ;45:234-241. Epub 2019 Jul 2. PMID: 31331567 Abstract Title: Usage of and attitudes about green tea extract and Epigallocathechin-3-gallate (EGCG) as a therapy in individuals with Down syndrome. Abstract: OBJECTIVE: Usage of and views concerning alternative therapies in the DS community are not well documented. Some positive effects of …
Nephroprotective and antioxidant effect of green tea against nicotine-induced nephrotoxicity
PMID: Appl Physiol Nutr Metab. 2019 Feb 25. Epub 2019 Feb 25. PMID: 30802143 Abstract Title: Nephroprotective and antioxidant effect of green tea (Camellia sinensis) against nicotine-induced nephrotoxicity in rats and characterization of its bioactive compounds by HPLC-DAD. Abstract: Nicotine (NT) is a potential inducer of oxidative stress, through which it can damage numerous biological …
Nicotine-induced oxidative stress contributes to EMT and stemness during neoplastic transformation in human kidney epithelial cells.
PMID: Toxicol Appl Pharmacol. 2019 Jul 1 ;374:65-76. Epub 2019 Apr 29. PMID: 31047982 Abstract Title: Nicotine-induced oxidative stress contributes to EMT and stemness during neoplastic transformation through epigenetic modifications in human kidney epithelial cells. Abstract: Nicotine is a component of cigarette smoke and mounting evidence suggests toxicity and carcinogenicity of tobacco smoke in kidney. …
These results indicate that chronic paternal nicotine exposure can impact the behavior of offspring.
PMID: Neurotoxicol Teratol. 2019 Jul – Aug;74:106808. Epub 2019 May 16. PMID: 31103693 Abstract Title: Paternal nicotine exposure in rats produces long-lasting neurobehavioral effects in the offspring. Abstract: Studies of intergenerational effects of parental chemical exposure have principally focused on maternal exposure, particularly for studies of adverse neurobehavioral consequences on the offspring. Maternal nicotine exposure …
Almond consumption may reduce the risk of cardiovascular disease.
PMID: Adv Nutr. 2019 Jun 27. Epub 2019 Jun 27. PMID: 31243439 Abstract Title: Almond Consumption and Risk Factors for Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Abstract: Evidence suggests that eating nuts may reduce the risk of cardiovascular disease (CVD). We conducted a systematic review and meta-analysis of randomized controlled …
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Green Space Does Your Heart Good – http://ow.ly/9TrV30pasdY pic.twitter.com/HyAqAWOOD1
Green Space Does Your Heart Good – http://ow.ly/9TrV30pasdY pic.twitter.com/HyAqAWOOD1
This study demonstrates a sex-dependent effect of nicotine on gut microbiome community composition, functional bacterial genes, and the fecal metabolome.
PMID: Chem Res Toxicol. 2017 12 18 ;30(12):2110-2119. Epub 2017 Nov 16. PMID: 29035044 Abstract Title: Nicotine Alters the Gut Microbiome and Metabolites of Gut-Brain Interactions in a Sex-Specific Manner. Abstract: As the primary active substance in tobacco, nicotine affects the activity of the central nervous system, and its effects are sex-dependent. There are complex …
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