Author Archives: Taylor Mercado

PMID:  Zhonghua Yu Fang Yi Xue Za Zhi. 2006 Sep ;40(5):314-8. PMID: 17166420 Abstract Title:  [Effects of vitamin C on the inhibition of human leucocyte antigen class I (HLA-I) expression of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. Abstract:  OBJECTIVE: To explore the putative effects of Vitamin C (Vit C) on inhibition …

Continue reading “Vitamin C pre-treatment at different dosages could reverse at some extent the inhibitive effects of deoxynivalenol on HLA-I expression of HPBMCs.”

PMID:  Br J Nutr. 2007 Jan ;97(1):19-26. PMID: 17217556 Abstract Title:  Dose-dependent modulation of the T cell proteome by ascorbic acid. Abstract:  To investigate the hypothesis that the micronutrient ascorbic acid can modulate the functional genome, T cells (CCRF-HSB2) were treated with ascorbic acid (up to 150 microM) for up to 24 h. Protein expression …

Continue reading “Dose-dependent modulation of the T cell proteome by ascorbic acid.”

PMID:  Med Sci Monit. 2007 Mar ;13(3):BR51-8. PMID: 17325628 Abstract Title:  A novel vitamin C preparation enhances neurite formation and fibroblast adhesion and reduces xenobiotic-induced T-cell hyperactivation. Abstract:  BACKGROUND: Vitamin C (ascorbic acid, ascorbate) has been shown to enhance neurite outgrowth, promote fibroblast adhesion during wound healing, and reduce xenobiotic-induced leukocyte hyperactivity and inflammatory damage. …

Continue reading “These data confirm the previous observations that vitamin C supplementation can promote neurite outgrowth.”

PMID:  Neonatology. 2007 ;91(1):54-60. Epub 2006 Nov 10. PMID: 17344653 Abstract Title:  Immunomodulatory effect of vitamin C on intracytoplasmic cytokine production in neonatal cord blood cells. Abstract:  BACKGROUND: Vitamin C (ascorbic acid) is an essential water-soluble antioxidant in cells and plasma. Besides metabolic functions, vitamin C is also known to contribute to immune homeostasis. Recently, …

Continue reading “These data suggest that vitamin C differentially influences intracytoplasmic cytokine production in adults and neonates.”

PMID:  Br J Nutr. 2007 Apr ;97(4):639-43. PMID: 17349075 Abstract Title:  Orange juice vs vitamin C: effect on hydrogen peroxide-induced DNA damage in mononuclear blood cells. Abstract:  The intake of fruits rich in vitamin C seems to increase the antioxidant defence of the organism. However, it is still not clear whether vitamin C alone is …

Continue reading “Orange juice vs vitamin C: effect on hydrogen peroxide-induced DNA damage in mononuclear blood cells.”

PMID:  Mutat Res. 2008 Jan 8 ;649(1-2):71-8. Epub 2007 Aug 6. PMID: 17851119 Abstract Title:  Modulation of gamma-ray-induced apoptosis in human peripheral blood leukocytes by famotidine and vitamin C. Abstract:  To study the radioprotective effects of vitamin C and famotidine against radiation-induced apoptosis in human peripheral blood leukocytes, peripheral blood was obtained from six healthy …

Continue reading “Modulation of gamma-ray-induced apoptosis in human peripheral blood leukocytes by famotidine and vitamin C.”

PMID:  Br J Nutr. 2007 Oct ;98 Suppl 1:S29-35. PMID: 17922955 Abstract Title:  Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Abstract:  Adequate intakes of micronutrients are required for the immune system to function efficiently. Micronutrient deficiency suppresses immunity by affecting innate, T cell mediated …

Continue reading “Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses.”

PMID:  Circ J. 2008 Apr ;72(4):654-9. PMID: 18362440 Abstract Title:  Vitamin C reversed malfunction of peripheral blood-derived mononuclear cells in smokers through antioxidant properties. Abstract:  BACKGROUND: Smoking impairs neovascularization, possibly, through the impaired function of peripheral blood-derived mononuclear cells (PB-MNCs). Thus, the mechanism of impaired function of PB-MNCs caused by chronic smoking was examined, and …

Continue reading “Vitamin C reversed malfunction of peripheral blood-derived mononuclear cells in smokers through antioxidant properties.”

PMID:  Radiat Res. 2008 Apr ;169(4):384-96. PMID: 18363433 Abstract Title:  Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation. Abstract:  The purpose of this study was to determine whether a dietary supplement consisting of L-selenomethionine, vitamin C, vitamin E succinate, alpha-lipoic acid and N-acetyl cysteine could improve the survival of mice after …

Continue reading “Dietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiation.”

PMID:  J Sports Med Phys Fitness. 2008 Jun ;48(2):217-24. PMID: 18427418 Abstract Title:  Effect of vitamin C supplementation on lipid peroxidation, muscle damage and inflammation after 30-min exercise at 75% VO2max. Abstract:  AIM: Hypothetically, supplementation with the antioxidant vitamins C could alleviate exercise-induced lipid peroxidation. The purpose of this study was to evaluate the effect …

Continue reading “Vitamin C supplementation prevented endurance exercise-induced lipid peroxidation and muscle damage but had no effect on inflammatory markers.”