Vitamin C in high oral dose was capable of enhancing NK activity up to ten-fold in 78% of patients.

PMID:  Immunopharmacol Immunotoxicol. 1997 Aug ;19(3):291-312. PMID: 9248859 Abstract Title:  Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C. Abstract:  After exposure to many toxic chemicals, NK function can be decreased significantly. Weeks or months later, natural …

TET enzymes and 5hmC in adaptive and innate immune systems.

PMID:  Front Immunol. 2019 ;10:210. Epub 2019 Feb 12. PMID: 30809228 Abstract Title:  TET Enzymes and 5hmC in Adaptive and Innate Immune Systems. Abstract:  DNA methylation is an abundant and stable epigenetic modification that allows inheritance of information from parental to daughter cells. At active genomic regions, DNA methylation can be reversed by TET (Ten-eleven …

High glucose intake exacerbates autoimmunity.

PMID:  Immunity. 2019 10 15 ;51(4):671-681.e5. Epub 2019 Aug 23. PMID: 31451397 Abstract Title:  High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation. Abstract:  Diet has been suggested to be a potential environmental risk factor for the increasing incidence of autoimmune diseases, yet the underlying mechanisms remain elusive. Here, we show that high glucose …

Boosting the immune system, from science to myth: analysis the infosphere with google.

PMID:  Front Med (Lausanne). 2019 ;6:165. Epub 2019 Jul 25. PMID: 31403046 Abstract Title:  Boosting the Immune System, From Science to Myth: Analysis the Infosphere With Google. Abstract:  The concept that one can"boost"immunity is a popular one. Although the only evidence-based approach to this is vaccination, the lay public is exposed to a wide range …

High-dose vitamin C enhances cancer immunotherapy.

PMID:  Sci Transl Med. 2020 Feb 26 ;12(532). PMID: 32102933 Abstract Title:  High-dose vitamin C enhances cancer immunotherapy. Abstract:  Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly …

Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D.

PMID:  J Nutr Biochem. 2020 Mar ;77:108240. Epub 2019 Oct 30. PMID: 31841960 Abstract Title:  Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D. Abstract:  A functional immune system is essential for healthy life. This is achieved by the coordinate activation and interaction of different immune cells. One should be aware that …

Essential role of vitamin C and zinc in child immunity and health.

PMID:  J Int Med Res. 2010 Mar-Apr;38(2):386-414. PMID: 20515554 Abstract Title:  Essential role of vitamin C and zinc in child immunity and health. Abstract:  With the progressive elimination of dietary protein-energy deficits, deficiencies of micronutrients are emerging as the limiting factors in ensuring children's optimal health. Data from several countries in Asia and Latin America …

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