Taylor Mercado

A review of Schisandra chinensis and its phytotherapeutical applications.

PMID: Ceska Slov Farm. 2019 ;68(3):95-118. PMID: 31431019 Abstract Title: Schisandra chinensis and its phytotherapeutical applications. Abstract: Schisandra (Schisandra chinensis) has been used for centuries as a plant of traditional Chinese medicine. Its biological activity and pharmacological use are associated with dibenzocyclooctadiene lignans, while specific polysaccharides may also be involved. The lignans of schisandra are genus-specific. …

Continue reading “A review of Schisandra chinensis and its phytotherapeutical applications.”

These results suggest that schisandrol B can alleviate the severity of asthma.

PMID: Food Funct. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32186565 Abstract Title: Investigation of the active components and mechanisms of Schisandra chinensis in the treatment of asthma based on a network pharmacology approach and experimental validation. Abstract: The aim of this paper was to investigate the active components of Schisandra chinensis in the …

Continue reading “These results suggest that schisandrol B can alleviate the severity of asthma.”

Schisandrin A protects against lipopolysaccharide-induced mastitis.

PMID: Int Immunopharmacol. 2020 Jan ;78:105983. Epub 2019 Nov 22. PMID: 31767544 Abstract Title: Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy. Abstract: Schisandrin A (Sch A), a dibenzocyclooctadiene lignan extracted from Schisandra chinensis (Turcz.) Baill., has anti-oxidant and anti-inflammatory effects, but the effect on masitits has not been …

Continue reading “Schisandrin A protects against lipopolysaccharide-induced mastitis.”

Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice.

PMID: Food Funct. 2019 Dec 11 ;10(12):7755-7766. PMID: 31696200 Abstract Title: Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice. Abstract: OBJECTIVE: To examine the anti-fatigue function of anwulignan from Schisandra and its underlying mechanism.METHODS: After an excessive fatigue mouse model was created, anwulignan was administered to the mice, and its …

Continue reading “Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice.”

Effect of methanol extract of Schisandrae Fructus on high fat diet induced hyperlipidemia.

PMID: J Tradit Chin Med. 2019 Dec ;39(6):818-825. PMID: 32186152 Abstract Title: Effect of methanol extract of Schisandrae Fructus on high fat diet induced hyperlipidemic mice. Abstract: OBJECTIVE: To investigate the effects and molecular targets of Schisandrae Fructus (SF) methanol extract (SFme) in mice with hyperlipidemia induced by high fat diet.METHODS: We observed changes in …

Continue reading “Effect of methanol extract of Schisandrae Fructus on high fat diet induced hyperlipidemia.”

These results suggest that S. chinensis acidic polysaccharide improves the insulin resistance in T2D by inhibiting inflammation.

PMID: J Med Food. 2020 Mar 16. Epub 2020 Mar 16. PMID: 32181695 Abstract Title: Acidic Polysaccharide Improves the Insulin Resistance in Type 2 Diabetic Rats by Inhibiting Inflammation. Abstract: Polysaccharide fromhas the effect of lowering blood glucose and improving insulin resistance (IR). However, its underlying mechanism remains unclear. In this study, a rat model …

Continue reading “These results suggest that S. chinensis acidic polysaccharide improves the insulin resistance in T2D by inhibiting inflammation.”

Schisandra extract and ascorbic acid synergistically enhance cognition.

PMID: Nutrients. 2020 Mar 25 ;12(4). Epub 2020 Mar 25. PMID: 32218327 Abstract Title: Schisandra Extract and Ascorbic Acid Synergistically Enhance Cognition in Mice Through Modulation of Mitochondrial Respiration. Abstract: Cognitive decline is observed in aging and neurodegenerative diseases, including Alzheimer's disease (AD) and dementia. Intracellular energy produced via mitochondrial respiration is used in the …

Continue reading “Schisandra extract and ascorbic acid synergistically enhance cognition.”

The bioflavonoid galangin suppresses the growth of ehrlich ascites carcinoma.

PMID: Appl Biochem Biotechnol. 2012 Jul ;167(5):1325-39. Epub 2012 Mar 21. PMID: 22434356 Abstract Title: The bioflavonoid galangin suppresses the growth of ehrlich ascites carcinoma in Swiss Albino mice: a molecular insight. Abstract: Bioflavonoids are plant compounds touted for their potential to treat or prevent several diseases including cancer caused by various stress conditions. Galangin …

Continue reading “The bioflavonoid galangin suppresses the growth of ehrlich ascites carcinoma.”

Galangin induces autophagy through upregulation of p53 in HepG2 cells.

PMID: Pharmacology. 2012 ;89(5-6):247-55. PMID: 22507894 Abstract Title: Galangin induces autophagy through upregulation of p53 in HepG2 cells. Abstract: AIM: To investigate the mechanism by which galangin, a polyphenolic compound derived from medicinal herbs,induces autophagy of HepG2 cells.METHODS: The MTT[3-(4,5-dimethyl-thiazol-2-yl)2,5-diphenyl-tetrazolium bromide]assay was used to measure cell viability. Apoptosis was evaluated by TUNEL assay with flow …

Continue reading “Galangin induces autophagy through upregulation of p53 in HepG2 cells.”

Galangin induces apoptosis in hepatocellular carcinoma cells.

PMID: J Asian Nat Prod Res. 2012 ;14(7):626-33. Epub 2012 May 10. PMID: 22575016 Abstract Title: Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway. Abstract: This study has investigated whether galangin, a flavonol derived from Alpinia officinarum Hance and used as food additives in southern China, induces apoptosis in hepatocellular …

Continue reading “Galangin induces apoptosis in hepatocellular carcinoma cells.”