PMID: Med Glas (Zenica). 2020 Aug 1 ;17(2). Epub 2020 Aug 1. PMID: 32153156 Abstract Title: A therapeutic effect of Nigella sativa extract on female Wistar rats vulvovaginal candidiasis model. Abstract: Aim Vulvovaginal candidiasis (VVC) is a disease mostly caused by Candida albicans and affects the quality of life of women especially in the form …
Author Archives: Taylor Mercado
Thymoquinone loaded solid lipid nanoparticles demonstrated antidepressant-like activity.
PMID: Drug Res (Stuttg). 2020 Mar 20. Epub 2020 Mar 20. PMID: 32198742 Abstract Title: Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway. Abstract: The World Health Organization (WHO) has ranked depression the 4leading cause of disability worldwide. Thymoquinone (TQ), is an active constituent ofhaving various medicinal …
Thymoquinone protection against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induced nephrotoxicit.
PMID: Biotech Histochem. 2020 Mar 24:1-8. Epub 2020 Mar 24. PMID: 32207631 Abstract Title: Thymoquinone protection against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induced nephrotoxicity in rats. Abstract: We investigated the effects of thymoquinone (TQ) on kidney tissues of Wistar rats with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced nephrotoxicity. We used 50 rats divided into five groups; control, corn oil, …
Thymoquinone attenuates IgE-mediated allergic response.
PMID: J Food Biochem. 2020 Mar 24:e13216. Epub 2020 Mar 24. PMID: 32212163 Abstract Title: Thymoquinone attenuates IgE-mediated allergic response via pi3k-Akt-NFκB pathway and upregulation of the Nrf2-HO1 axis. Abstract: IgE-dependent reactions mediate the majority of allergic diseases. This study explores the effects of thymoquinone (Tq) on IgE-mediated allergic response in activated mast cells, basophils, …
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Low doses of thymoquinone and ferulic acid in combination effectively inhibit proliferation of cultured MDA-MB 231 breast adenocarcinoma cells.
PMID: Nutr Cancer. 2020 Mar 28:1-8. Epub 2020 Mar 28. PMID: 32223348 Abstract Title: Low Doses of Thymoquinone and Ferulic Acid in Combination Effectively Inhibit Proliferation of Cultured MDA-MB 231 Breast Adenocarcinoma Cells. Abstract: Thymoquinone (TQ) and Ferulic Acid (FA) are natural ingredients fromand, respectively. Individually both TQ and FA have shown anticancer properties in …
Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis.
PMID: Int Immunopharmacol. 2020 Mar 12 ;83:106379. Epub 2020 Mar 12. PMID: 32172206 Abstract Title: Ferulic acid isolated from propolis inhibits porcine parvovirus replication potentially through Bid-mediate apoptosis. Abstract: Propolis from honeybee hives, which is a traditional Chinese medicine, is widely used in veterinary clinics. Many compounds have been identified and isolated from propolis. Ferulic …
Anticatabolic and anti-inflammatory effects of myricetin 3-O-β-d-galactopyranoside in UVA-irradiated dermal cells.
PMID: Molecules. 2020 Mar 14 ;25(6). Epub 2020 Mar 14. PMID: 32183404 Abstract Title: Anticatabolic and Anti-Inflammatory Effects of Myricetin 3-O-β-d-Galactopyranoside in UVA-Irradiated Dermal Cells via Repression of MAPK/AP-1 and Activation of TGFβ/Smad. Abstract: UV irradiation is one of the main causes of extrinsic skin aging. UV-mediated skin aging, also known as photoaging, causes excessive …
Myricetin modulates macrophage polarization and mitigates liver inflammation and fibrosis in a murine model of nonalcoholic steatohepatitis.
PMID: Front Med (Lausanne). 2020 ;7:71. Epub 2020 Mar 4. PMID: 32195263 Abstract Title: Myricetin Modulates Macrophage Polarization and Mitigates Liver Inflammation and Fibrosis in a Murine Model of Nonalcoholic Steatohepatitis. Abstract: This study aimed to investigate the beneficial effects of myricetin in a diet-induced nonalcoholic steatohepatitis (NASH) model and the underlying mechanism. C57BL/6J mice …
The present findings highlight a novel role for galangin as a promising anti-remodelling agent in asthma.
PMID: Sci Rep. 2015 Jul 9 ;5:11758. Epub 2015 Jul 9. PMID: 26156213 Abstract Title: Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma. Abstract: Galangin, a natural flavonol, has attracted much attention for its potential anti-inflammatory properties. However, its role in the regulation of airway remodelling in asthma has …
Galangin provides significant protection against acetaminophen induced liver and kidney damage.
PMID: J Med Food. 2015 Nov ;18(11):1187-97. Epub 2015 Jun 4. PMID: 26501381 Abstract Title: Galangin Prevents Acute Hepatorenal Toxicity in Novel Propacetamol-Induced Acetaminophen-Overdosed Mice. Abstract: Acetaminophen (APAP) overdose causes severe liver and kidney damage. APAP-induced liver injury (AILI) represents the most frequent cause of drug-induced liver failure. APAP is relatively insoluble and can only …
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