Taylor Mercado

Galangin inhibits hypertrophic scar formation via ALK5/Smad2/3 signaling pathway.

PMID: Mol Cell Biochem. 2016 Feb ;413(1-2):109-18. Epub 2016 Jan 4. PMID: 26728998 Abstract Title: Galangin inhibits hypertrophic scar formation via ALK5/Smad2/3 signaling pathway. Abstract: Hypertrophic scar (HS) is characterized by excessive fibrosis associated with aberrant function of fibroblasts. Currently, no satisfactory drug has been developed to treat the disease. Here we found that a …

Continue reading “Galangin inhibits hypertrophic scar formation via ALK5/Smad2/3 signaling pathway.”

Galangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma.

PMID: Mol Med Rep. 2016 May ;13(5):4238-44. Epub 2016 Mar 24. PMID: 27035542 Abstract Title: Galangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma. Abstract: Galangin, a flavonoid extracted from the root of the Alpinia officinarum Hence, has been shown to have anticancer properties against several types of cancer …

Continue reading “Galangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma.”

Galangin induces autophagy via deacetylation of LC3 by SIRT1 in HepG2 cells.

PMID: Sci Rep. 2016 07 27 ;6:30496. Epub 2016 Jul 27. PMID: 27460655 Abstract Title: Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells. Abstract: Galangin suppresses proliferation and induces apoptosis and autophagy in hepatocellular carcinoma (HCC) cells, but the precise mechanism is not clear. In this study, we demonstrated that galangin …

Continue reading “Galangin induces autophagy via deacetylation of LC3 by SIRT1 in HepG2 cells.”

Dr. Fauci NEJM Editorial Suggests That COVID-19 Fatality Rates May Be 10x Lower Than Official Projections

This article is copyrighted by GreenMedInfo LLC, 2020Visit our Re-post guidelines Dr. Fauci, whose guidance to President Trump has resulted in a near total lockdown of the country, recently published an editorial in New England Journal of Medicine that rightly points out serious flaws in his own doom-and-gloom COVID-19 fatality projections. read more

These results suggest that lemon balm extract increases cell proliferation, neuroblast differentiation and integration into granule cells by decreasing serum corticosterone levels as well as by increasing GABA levels in the mouse dentate gyrus.

PMID: Neurochem Res. 2011 Feb ;36(2):250-7. Epub 2010 Nov 13. PMID: 21076869 Abstract Title: Effects of Melissa officinalis L. (lemon balm) extract on neurogenesis associated with serum corticosterone and GABA in the mouse dentate gyrus. Abstract: Lemon balm, leaves of Melissa officinalis L., has been used for anti-anxiety and spasmolytics. We observed the extract of …

Continue reading “These results suggest that lemon balm extract increases cell proliferation, neuroblast differentiation and integration into granule cells by decreasing serum corticosterone levels as well as by increasing GABA levels in the mouse dentate gyrus.”

These findings suggest that lemon balm extract has a mild protective effect against reperfusion-induced lethal ventricular arrhythmias in rats.

PMID: Med Princ Pract. 2014 ;23(4):340-5. Epub 2014 Jun 18. PMID: 24942615 Abstract Title: Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone. Abstract: OBJECTIVE: We aimed to assess the influence of Melissa officinalis (lemon balm), a well-known herbal drug with numerous applications in traditional and modern …

Continue reading “These findings suggest that lemon balm extract has a mild protective effect against reperfusion-induced lethal ventricular arrhythmias in rats.”

Lemon balm extract suppresses adipogenesis and adipocyte hypertrophy.

PMID: J Ethnopharmacol. 2016 Feb 3 ;178:238-50. Epub 2015 Dec 15. PMID: 26702505 Abstract Title: The anti-angiogenic herbal extract from Melissa officinalis inhibits adipogenesis in 3T3-L1 adipocytes and suppresses adipocyte hypertrophy in high fat diet-induced obese C57BL/6J mice. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Melissa officinalis L. (Labiatae; lemon balm) has been used traditionally and contemporarily as an …

Continue reading “Lemon balm extract suppresses adipogenesis and adipocyte hypertrophy.”

Lemon balm is safe at a 500mg dose of rosmarinic acid in healthy individuals.

PMID: PLoS One. 2015 ;10(5):e0126422. Epub 2015 May 15. PMID: 25978046 Abstract Title: Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial. Abstract: The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained …

Continue reading “Lemon balm is safe at a 500mg dose of rosmarinic acid in healthy individuals.”

The data show that a two-week treatment with plant extracts affects the dysbiotic gut microbiota and changes both caecum metabolome and markers of lipid metabolism in ob/ob mice.

PMID: Mol Nutr Food Res. 2019 09 ;63(17):e1900403. Epub 2019 Jun 25. PMID: 31206248 Abstract Title: A Two-Week Treatment with Plant Extracts Changes Gut Microbiota, Caecum Metabolome, and Markers of Lipid Metabolism in ob/ob Mice. Abstract: SCOPE: Targeting gut microbiota dysbiosis by prebiotics is effective, though side effects such as abdominal bloating and flatulence may …

Continue reading “The data show that a two-week treatment with plant extracts affects the dysbiotic gut microbiota and changes both caecum metabolome and markers of lipid metabolism in ob/ob mice.”

Lemon balm decreases the serum triglyceride level in dyslipidemic diabetic patients.

PMID: J Complement Integr Med. 2019 Jan 25 ;16(3). Epub 2019 Jan 25. PMID: 30681971 Abstract Title: The effects of a Melissa officinalis L. based product on metabolic parameters in patients with type 2 diabetes mellitus: A randomized double-blinded controlled clinical trial. Abstract: Background Diabetic patients are at increased risk for coronary artery disease. Since …

Continue reading “Lemon balm decreases the serum triglyceride level in dyslipidemic diabetic patients.”