Lemon balm extracts protect human retinal pigment epithelial cells against oxidative stress-induced apoptosis.

PMID:  Int J Med Sci. 2016 ;13(2):139-46. Epub 2016 Feb 3. PMID: 26941573 Abstract Title:  Melissa Officinalis L. Extracts Protect Human Retinal Pigment Epithelial Cells against Oxidative Stress-Induced Apoptosis. Abstract:  BACKGROUND: We evaluated the protective effect of ALS-L1023, an extract of Melissa officinalis L. (Labiatae; lemon balm) against oxidative stress-induced apoptosis in human retinal pigment …

Lemon balm ameliorates the harmful effects of varicocele on sperm parameters and chromatin structure.

PMID:  Andrologia. 2018 Oct ;50(8):e13058. Epub 2018 Jun 6. PMID: 29876952 Abstract Title:  Can Melissa officinalis improve chromatin structure and sperm parameters in a rat model of varicocele? Abstract:  Excessive production of reactive oxygen species is a central mechanism in the pathology of varicocele; Melissa officinalis (MO) is a medicinal plant from the Lamiaceae family …

In a study of 918 children, valerian and lemon balm reduced dyssomnia and restlessness symptoms from moderate/severe to mild or absent in most patients.

PMID:  Phytomedicine. 2006 Jun ;13(6):383-7. Epub 2006 Feb 17. PMID: 16487692 Abstract Title:  A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Abstract:  Efficacy and tolerability of a combined valerian/lemon balm preparation were investigated in an open, multicentre study in children less than 12 years suffering …

Lemon balm leaf extract displays antiplatelet activity.

PMID:  Nat Prod Commun. 2017 Jan ;12(1):93-94. PMID: 30549835 Abstract Title:  Quantitative Analysis of Phenolic Acids and Antiplatelet Activity of Melissa officinalis Leaf Extracts. Abstract:  The contents of total phenolic acids and rosmarinic acid were determined and the antiplatelet potential assessed of extracts of lemon balm (Melissa officinalis L., Lamiaceae) leaf samples collected during 2014 …

Lemon balm essential oil inhibits antiviral activity against avian influenza A virus.

PMID:  Virusdisease. 2016 Jun ;27(2):170-8. Epub 2016 May 21. PMID: 27366768 Abstract Title:  Antiviral activity of the oseltamivir and Melissa officinalis L. essential oil against avian influenza A virus (H9N2). Abstract:  Lemon balm derivatives are going to acquire a novelty as natural and potent remedy for treatment of viral infections since the influenza viruses are …

Lemon balm displays effects on the contractile activity of the gastrointestinal tract.

PMID:  J Med Food. 2019 Jul ;22(7):653-662. Epub 2019 Apr 16. PMID: 30990736 Abstract Title:  Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract ofL. on Intestinal Motility: AnStudy. Abstract:  L. (lemon balm) has been used for decades with symptomatic benefits in patients with digestive disorders. However, very little is known on the effects ofon …

Lemon balm extract displays anti-glycative properties.

PMID:  Food Chem. 2011 Nov 15 ;129(2):267-271. Epub 2011 Apr 20. PMID: 30634225 Abstract Title:  Inhibitory effects of Lemon balm (Melissa officinalis, L.) extract on the formation of advanced glycation end products. Abstract:  Lemon balm (Melissa officinalis) is a medicinal herb possessing functional compounds with unexplored anti-glycative action. The anti-glycative activity of Lemon balm extract …

Lemon balm may protect improve resistance of the heart to myocardial injury.

PMID:  Pharm Biol. 2016 ;54(6):1005-13. Epub 2015 Oct 12. PMID: 26457827 Abstract Title:  The effects of Melissa officinalis (lemon balm) pretreatment on the resistance of the heart to myocardial injury. Abstract:  CONTEXT: The antihyperlipidemic, antiarrhythmic, neuroprotective and hepatoprotective effects of Melissa officinalis L. (Lamiaceae) have been reported. However, no study has examined its effects on …

An anti-angiogenic compound from lemon balm leaves attenuates a high-fat diet-induced nonalcoholic fatty liver disease.

PMID:  Int J Mol Sci. 2017 Apr 17 ;18(4). Epub 2017 Apr 17. PMID: 28420164 Abstract Title:  The Angiogenesis Inhibitor ALS-L1023 from Lemon-Balm Leaves Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Regulating the Visceral Adipose-Tissue Function. Abstract:  Similar to neoplastic tissues, growth and development of adipose tissue are thought to be angiogenesis-dependent. Since visceral …

Lemon balm decreases HbA1c and improves beta-cell activity, blood pressure, and HDL-C in type 2 diabetic individuals.

PMID:  Phytother Res. 2019 Mar ;33(3):651-659. Epub 2018 Dec 10. PMID: 30548118 Abstract Title:  Efficacy of Melissa officinalis L. (lemon balm) extract on glycemic control and cardiovascular risk factors in individuals with type 2 diabetes: A randomized, double-blind, clinical trial. Abstract:  Melissa officinalis is a plenteous source of antioxidant flavonols and flavonoids that contain health-promoting …

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