This article is copyrighted by GreenMedInfo LLC, 2020Visit our Re-post guidelines As the world, and the United States, waits anxiously for news of when the outbreak and lockdown will end, two new plans outline requirements that will significantly impact our already suspended civil liberties. read more
Author Archives: Taylor Mercado
Galangin could suppress the viability of MCF-7 cells and induce cell apoptosis.
PMID: Pharmacology. 2018 ;102(1-2):58-66. Epub 2018 Jun 7. PMID: 29879712 Abstract Title: Galangin Induces Apoptosis in MCF-7 Human Breast Cancer Cells Through Mitochondrial Pathway and Phosphatidylinositol 3-Kinase/Akt Inhibition. Abstract: AIMS: The study aimed to investigate the molecular mechanism of inhibition of proliferation and apoptosis induction by galangin against MCF-7 human breast cancer cells.METHODS: Cell Counting …
Continue reading “Galangin could suppress the viability of MCF-7 cells and induce cell apoptosis.”
Administration of galangin reduced hyperlipidaemia related to the risk of diabetic complications.
PMID: Pharm Biol. 2018 Dec ;56(1):302-308. PMID: 29952676 Abstract Title: Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia. Abstract: CONTEXT: Galangin, a natural flavonoid, is found in honey and Alpinia officinarum Hance (Zingiberaceae). Galangin has antiviral, antimicrobial, antidiabetic and anticancer properties, without side effects. The effects of galangin on …
Galangin inhibited lipopolysaccharide-induced neuroinflammation.
PMID: Mol Cell Biochem. 2019 Jan ;451(1-2):145-153. Epub 2018 Jul 11. PMID: 29995265 Abstract Title: Anti-neuroinflammatory effects of galangin in LPS-stimulated BV-2 microglia through regulation of IL-1β production and the NF-κB signaling pathways. Abstract: Neuroinflammation resulting from microglial activation is involved in the pathogenesis of neurodegenerative diseases, including Parkinson's diseases. Microglial activation plays an important …
Continue reading “Galangin inhibited lipopolysaccharide-induced neuroinflammation.”
Galangin could prove a useful new molecule in the treatment of kidney carcinoma.
PMID: J BUON. 2018 May-Jun;23(3):795-799. PMID: 30003754 Abstract Title: Galangin induced antitumor effects in human kidney tumor cells mediated via mitochondrial mediated apoptosis, inhibition of cell migration and invasion and targeting PI3K/ AKT/mTOR signalling pathway. Abstract: PURPOSE: Galangin is an important flavonoid that has been reported to be of immense pharmacological importance. It has been …
Continue reading “Galangin could prove a useful new molecule in the treatment of kidney carcinoma.”
Galangin inhibits α-glucosidase activity and formation of non-enzymatic glycation products.
PMID: Food Chem. 2019 Jan 15 ;271:70-79. Epub 2018 Jul 24. PMID: 30236734 Abstract Title: Galangin inhibitsα-glucosidase activity and formation of non-enzymatic glycation products. Abstract: Inhibition ofα-glucosidase and non-enzymatic glycation is considered as an effective approach to treat type 2 diabetes. Herein, multispectroscopic techniques and molecular docking analysis were used to investigate the inhibition of …
Galangin alleviates liver ischemia-reperfusion injury.
PMID: Cell Physiol Biochem. 2018 ;51(3):1354-1363. Epub 2018 Nov 27. PMID: 30481779 Abstract Title: Galangin Alleviates Liver Ischemia-Reperfusion Injury in a Rat Model by Mediating the PI3K/AKT Pathway. Abstract: BACKGROUND/AIMS: Liver ischemia-reperfusion (I/R) injury is a pathological process that often occurs during liver and trauma surgery. There are numerous causes of liver I/R injury, but …
Continue reading “Galangin alleviates liver ischemia-reperfusion injury.”
Chemopreventive mechanisms of galangin against hepatocellular carcinoma.
PMID: Biomed Pharmacother. 2019 Jan ;109:2054-2061. Epub 2018 Nov 26. PMID: 30551461 Abstract Title: Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review. Abstract: Hepatocellular carcinoma (HCC) is one of the most common cancers and has a high mortality rate in less developed countries, especially in China. Galangin (GA), one of the most important and …
Continue reading “Chemopreventive mechanisms of galangin against hepatocellular carcinoma.”
Galangin prevents increased susceptibility to pentylenetetrazol-stimulated seizures by prostaglandin E2.
PMID: Neuroscience. 2019 08 10 ;413:154-168. Epub 2019 Jun 11. PMID: 31200106 Abstract Title: Galangin Prevents Increased Susceptibility to Pentylenetetrazol-Stimulated Seizures by Prostaglandin E2. Abstract: Epilepsy is one of the most common chronic neurological diseases. It is characterized by recurrent epileptic seizures, where one-third of patients are refractory to existing treatments. Evidence revealed the association …
Galangin might represent a promising adjuvant therapy to prevent hepatotoxicity in patients on cyclophosphamide treatment.
PMID: Biomolecules. 2019 08 5 ;9(8). Epub 2019 Aug 5. PMID: 31387329 Abstract Title: Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity. Abstract: Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical application is limited because of its multi-organ toxicity. Galangin (Gal) is …