PMID: Int J Mol Sci. 2015 Jun 2 ;16(6):12424-35. Epub 2015 Jun 2. PMID: 26042464 Abstract Title: Induction of Apoptosis in Endometrial Cancer (Ishikawa) Cells by Pogostemon cablin Aqueous Extract (PCAE). Abstract: Pogostemon cablin (PC) is a traditional herbal medicine used in the treatment of the common cold, nausea, diarrhea, and even for headaches and …
Author Archives: Taylor Mercado
Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin.
PMID: Int J Mol Med. 2016 Jan ;37(1):217-24. Epub 2015 Nov 3. PMID: 26531835 Abstract Title: Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin. Abstract: Allergic disease is caused by exposure to normally innocuous substances that activate mast cells. Mast cell-mediated allergic inflammation is closely related to a number of allergic disorders, such …
Protective effects of patchouli alcohol isolated from Pogostemon cablin on lipopolysaccharide-induced acute lung injury in mice.
PMID: Exp Ther Med. 2016 Feb ;11(2):674-682. Epub 2015 Dec 8. PMID: 26893665 Abstract Title: Protective effects of patchouli alcohol isolated fromon lipopolysaccharide-induced acute lung injury in mice. Abstract: Patchouli alcohol (PA) is a tricyclic sesquiterpene isolated from Pogostemon cablin, which exerts anti-inflammatory, anti-influenza and cognitive-enhancing bioactivities. The present study aimed to investigate the protective …
Patchouli alcohol protects against Helicobacter pylori urease-induced apoptosis, oxidative stress and inflammatory response in human gastric epithelial cells.
PMID: Int Immunopharmacol. 2016 Jun ;35:43-52. Epub 2016 Mar 24. PMID: 27017292 Abstract Title: (-)-Patchouli alcohol protects against Helicobacter pylori urease-induced apoptosis, oxidative stress and inflammatory response in human gastric epithelial cells. Abstract: (-)-Patchouli alcohol (PA), the major active principle of Pogostemonis Herba, has been reported to have anti-Helicobacter pylori and gastroprotective effects. In the …
Patchouli alcohol attenuates experimental atherosclerosis via inhibiting macrophage infiltration and its inflammatory responses.
PMID: Biomed Pharmacother. 2016 Oct ;83:930-935. Epub 2016 Aug 11. PMID: 27522255 Abstract Title: Patchouli alcohol attenuates experimental atherosclerosis via inhibiting macrophage infiltration and its inflammatory responses. Abstract: Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from a traditional Chinese herb pogostemonis herba. Literatures have proven that PA could inhibit inflammatory responses in various inflammatory …
Patchouli alcohol might be able to serve as a novel antitumor compound in the clinical treatment of lung cancer.
PMID: Biomed Res Int. 2016 ;2016:4567580. Epub 2016 Oct 17. PMID: 27830146 Abstract Title: Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cellsand. Abstract: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing(also known as"Guang-Huo-Xiang") have been widely used in Chinese medicine today. In …
Transformation of patchouli alcohol to β-patchoulene by gastric juice: β-patchoulene is more effective in preventing ethanol-induced gastric injury.
PMID: Sci Rep. 2017 07 17 ;7(1):5591. Epub 2017 Jul 17. PMID: 28717228 Abstract Title: Transformation of patchouli alcohol toβ-patchoulene by gastric juice: β-patchoulene is more effective in preventing ethanol-induced gastric injury. Abstract: Pogostemonis Herba is a functional food approved in Asian countries. Its major constituent, patchouli alcohol (PA), possesses a gastroprotective effect and is …
T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis.
PMID: Mol Med Rep. 2017 Oct ;16(4):4511-4520. Epub 2017 Aug 2. PMID: 28791344 Abstract Title: T cell inhibition by pogostone from Pogostemon cablin (Blanco) Benth: In vitro and in vivo immunosuppressive analysis. Abstract: Various plant-derived compounds exhibit immunosuppressive activity in pre‑clinical investigations, suggesting that they may serve as natural alternatives for the prevention of inflammatory disorders and autoimmune …
Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer.
PMID: Phytomedicine. 2018 Jan 15 ;39:111-118. Epub 2017 Dec 25. PMID: 29433672 Abstract Title: Protective role ofβ-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis. Abstract: BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are most widely used as effective anti-inflammatory agents. However, their clinical application brings about inevasible gastrointestinal side effects. …
Patchouli alcohol has the potential to be a promising candidate for treatment of H. pylori-related diseases.
PMID: Front Pharmacol. 2018 ;9:1347. Epub 2018 Nov 22. PMID: 30524287 Abstract Title: Unraveling the Novel Protective Effect of Patchouli Alcohol Against-Induced Gastritis: Insights Into the Molecular Mechanismand. Abstract: Patchouli alcohol (PA), a natural tricyclic sesquiterpene extracted from(Blanco) Benth. (Labiatae), has been found to exhibit anti-and anti-inflammatory properties. In this study, we investigated the protective …
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