PMID: Int Immunopharmacol. 2019 Mar ;68:7-16. Epub 2018 Dec 29. PMID: 30599446 Abstract Title: Effect of patchouli alcohol on Helicobacter pylori-induced neutrophil recruitment and activation. Abstract: Neutrophil infiltration typically occurs in Helicobacter pylori (H. pylori)-induced acute gastritis; however, this immune response fails to eradicate H. pylori in vivo. Moreover, reactive oxygen species (ROS), which are …
Author Archives: Taylor Mercado
Effect of patchouli essential oil on in vitro and in vivo leukocytes behavior in acute inflammatory response.
PMID: Biomed Pharmacother. 2016 Dec ;84:1697-1704. Epub 2016 Nov 12. PMID: 27847207 Abstract Title: Effect of patchouli (Pogostemon cablin) essential oil on in vitro and in vivo leukocytes behavior in acute inflammatory response. Abstract: PURPOSE: The aim of this study was to evaluate the effect of Pogostemon cablin essential oil (PEO) on leukocyte behavior in …
Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways.
PMID: Int Immunopharmacol. 2018 Sep ;62:15-22. Epub 2018 Jun 30. PMID: 29966943 Abstract Title: Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways. Abstract: Pogostone (PO), a major component of Pogostemon cablin, displays potent protective effects against lipopolysaccharide-induced acute lung injury (ALI) in mice. This study aimed to investigate the …
Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis.
PMID: J Ethnopharmacol. 2020 Mar 25 ;250:112519. Epub 2019 Dec 25. PMID: 31883475 Abstract Title: Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Pogostemon cablin, commonly named"Guang-Huo-Xiang"in China, has long been renowned for its ability to dispel dampness and regulate gastrointestinal functions. Patchouli oil …
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Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism.
PMID: Pharmacol Res. 2017 Jul ;121:70-82. Epub 2017 Apr 27. PMID: 28456683 Abstract Title: Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism. Abstract: Despite the increased morbidity of ulcerative colitis (UC) in recent years, available treatments remain unsatisfactory. Pogostemon cablin has been widely applied to treat a variety of gastrointestinal disorders …
β-Patchoulene from patchouli oil protects against LPS-induced acute lung injury.
PMID: Int Immunopharmacol. 2017 Sep ;50:270-278. Epub 2017 Jul 13. PMID: 28711783 Abstract Title: β-Patchoulene from patchouli oil protects against LPS-induced acute lung injury via suppressing NF-κB and activating Nrf2 pathways. Abstract: β-Patchoulene (β-PAE), a tricyclic sesquiterpene isolated from the essential oil of the leaves and stems of Pogostemon cablin (Blanco) Benth., has been reported …
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Anti-nociceptive effect of patchouli alcohol.
PMID: Chin J Integr Med. 2019 Jun ;25(6):454-461. Epub 2017 Aug 9. PMID: 28795389 Abstract Title: Anti-nociceptive effect of patchouli alcohol: Involving attenuation of cyclooxygenase 2 and modulation of mu-opioid receptor. Abstract: OBJECTIVE: To explore the anti-nociceptive effect of patchouli alcohol (PA), the essential oil isolated from Pogostemon cablin (Blanco) Bent, and determine the mechanism …
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Patchouli oil ameliorates acute colitis.
PMID: Exp Ther Med. 2017 Aug ;14(2):1184-1192. Epub 2017 Jun 12. PMID: 28810577 Abstract Title: Patchouli oil ameliorates acute colitis: A targeted metabolite analysis of 2,4,6-trinitrobenzenesulfonic acid-induced rats. Abstract: The incidence of inflammatory bowel disease (IBD), characterized by chronic, relapsing intestinal inflammation, has continually increased in recent years. A previous study by our group identified …
Mechanism of anti-Helicobacter pylori urease activity of patchouli alcohol.
PMID: Zhongguo Zhong Yao Za Zhi. 2017 Feb ;42(3):562-566. PMID: 28952265 Abstract Title: [Mechanism of anti-Helicobacter pylori urease activity of patchouli alcohol]. Abstract: To investigate the effect of patchouli alcohol on inhibiting Helicobater pylori urease activity, and its effect on expression levels of related genes, and lay the foundation for further research on the effect …
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Patchoulene epoxide isolated from patchouli oil suppresses acute inflammation.
PMID: Mediators Inflamm. 2017 ;2017:1089028. Epub 2017 Jul 25. PMID: 28811678 Abstract Title: Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-B and Downregulation of COX-2/iNOS. Abstract: According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, of which an unknown compound identified as patchoulene epoxide (PAO) …
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