Green tea attenuates a chromogranin A increase after a mental task stress.

PMID:  J Physiol Anthropol. 2014 Jul 17 ;33:20. Epub 2014 Jul 17. PMID: 25034805 Abstract Title:  Intake of green tea inhibited increase of salivary chromogranin A after mental task stress loads. Abstract:  BACKGROUND: Green tea has become renowned for its health benefits. In this study, we investigated the anti-stress effect of two kinds of green …

Mate tea reduces high fat diet-induced liver and metabolic disorders in mice.

PMID:  Biomed Pharmacother. 2019 Jan ;109:1547-1555. Epub 2018 Nov 14. PMID: 30551407 Abstract Title:  Mate tea reduces high fat diet-induced liver and metabolic disorders in mice. Abstract:  High-fat diet (HFD)-induced obesity is a worldwide health problem and can cause lipid accumulation in the liver. We evaluated the hepatoprotective effect of mate tea treatment in mice …

Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome.

PMID:  World J Gastroenterol. 2018 Feb 14 ;24(6):693-705. PMID: 29456408 Abstract Title:  Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome. Abstract:  AIM: To elucidate the mechanism of patchouli alcohol (PA) in treatment of rat models of diarrhea-predominant irritable bowel syndrome (IBS-D).METHODS: We studied the effects of PA on colonic spontaneous motility using …

In vitro anti-hepatoma activities of notoginsenoside R1 through downregulation of tumor promoter miR-21.

PMID:  Dig Dis Sci. 2019 Sep 26. Epub 2019 Sep 26. PMID: 31559550 Abstract Title:  In Vitro Anti-hepatoma Activities of Notoginsenoside R1 Through Downregulation of Tumor Promoter miR-21. Abstract:  BACKGROUND: Notoginsenoside R1 (NG-R1) is the predominant active ingredient and a novel triterpene saponin compound extracted from the roots of Panax notoginseng. To date, to the …

Ginsenoside Rd ameliorates high fat diet-induced obesity.

PMID:  Obesity (Silver Spring). 2020 Apr ;28(4):783-792. Epub 2020 Mar 6. PMID: 32144882 Abstract Title:  Ginsenoside Rd Ameliorates High Fat Diet-Induced Obesity by Enhancing Adaptive Thermogenesis in a cAMP-Dependent Manner. Abstract:  OBJECTIVE: With the discovery of thermogenic adipocytes in humans, it has been hypothesized that enhancing adaptive thermogenesis may improve obesity. Although many studies have found …

Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo.

PMID:  Phytomedicine. 2020 Feb 26 ;69:153197. Epub 2020 Feb 26. PMID: 32146298 Abstract Title:  Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo by modulating toll-like receptor 4 dimerization and NF-kB/MAPKs signaling pathways. Abstract:  BACKGOUND: Ginsenoside Rb1, the main active constituent of Panax ginseng, displays significant anti-inflammatory activity, although the mechanism has not been …

Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter.

PMID:  J Ginseng Res. 2020 Mar ;44(2):247-257. Epub 2018 Nov 8. PMID: 32148406 Abstract Title:  Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter:andstudy. Abstract:  Background: Multidrug resistance (MDR) to chemotherapy drugs remains a major challenge in clinical cancer treatment. Here we investigated whether and how ginsenoside Rg5 overcomes the MDR mediated by ABCB1 …

Ginsenoside Rb1 is a potential natural glutathione reductase agonist that protects against oxidative stress-induced apoptosis of H9C2 cells.

PMID:  J Ginseng Res. 2020 Mar ;44(2):258-266. Epub 2018 Dec 16. PMID: 32148407 Abstract Title:  The role of ginsenoside Rb1, a potential natural glutathione reductase agonist, in preventing oxidative stress-induced apoptosis of H9C2 cells. Abstract:  Background: Oxidative stress-induced cardiomyocytes apoptosis is a key pathological process in ischemic heart disease. Glutathione reductase (GR) reduces glutathione disulfide …

Combining Rp1 with chemotherapeutic agents could circumvent drug resistance and improve treatment efficacy.

PMID:  Cancers (Basel). 2020 Mar 5 ;12(3). Epub 2020 Mar 5. PMID: 32151067 Abstract Title:  Ginsenoside Rp1, A Ginsenoside Derivative, Augments Anti-Cancer Effects of Actinomycin D via Downregulation of an AKT-SIRT1 Pathway. Abstract:  Novel strategies for overcoming multidrug resistance are urgently needed to improve chemotherapy success and reduce side effects. Ginsenosides, the main active components …

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