This article is copyrighted by GreenMedInfo LLC, 2020Visit our Re-post guidelines Ben Swann: As Governors and Mayors across the country are instituting “Stay at Home” Orders, there are big questions surrounding how parts of the government may be taking advantage of the coronavirus outbreak in violation of 1st, 2nd and 4th amendment rights of …
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Ginsenoside Rd attenuates blood-brain barrier damage by suppressing proteasome-mediated signaling after transient forebrain ischemia.
PMID: Neuroreport. 2020 Mar 12. Epub 2020 Mar 12. PMID: 32168101 Abstract Title: Ginsenoside Rd attenuates blood-brain barrier damage by suppressing proteasome-mediated signaling after transient forebrain ischemia. Abstract: Ischemic stroke damages the blood-brain barrier (BBB), which leads to brain edema and increases the risk of intracranial hemorrhage. Proteasome inhibition has been found to protect the …
Ginsenoside Rg3 attenuates aluminum-induced osteoporosis.
PMID: Biol Trace Elem Res. 2020 Mar 16. Epub 2020 Mar 16. PMID: 32173789 Abstract Title: Ginsenoside Rg3 Attenuates Aluminum-Induced Osteoporosis Through Regulation of Oxidative Stress and Bone Metabolism in Rats. Abstract: Aluminum (Al)-induced bone metabolism disorder is a primary cause of osteoporosis. Ginsenoside Rg3 (Rg3) has demonstrated therapeutic properties in the treatment of osteoporosis. …
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Ginsenoside Rg1 protects against cigarette smoke-induced airway remodeling.
PMID: Am J Transl Res. 2020 ;12(2):493-506. Epub 2020 Feb 15. PMID: 32194898 Abstract Title: Ginsenoside Rg1 protects against cigarette smoke-induced airway remodeling by suppressing the TGF-β1/Smad3 signaling pathway. Abstract: Chronic obstructive pulmonary disease (COPD) is a devastating and common respiratory disease characterized by chronic inflammation and progressive airway remodeling. Ginsenoside Rg1 (GRg1), a major …
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Neuroprotective triterpene saponins from the leaves of Panax notoginseng.
PMID: Nat Prod Res. 2019 Oct 22:1-7. Epub 2019 Oct 22. PMID: 31638430 Abstract Title: Neuroprotective triterpene saponins from the leaves of. Abstract: Two new triterpene saponins, namely notoginsenoside Ng5 () and notoginsenoside Ng6 () were isolated from the leaves of, along with five known ones. Their structures were determined by chemical methods, NMR and …
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Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes.
PMID: Int J Mol Med. 2020 Apr ;45(4):1225-1236. Epub 2020 Feb 6. PMID: 32124939 Abstract Title: Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes. Abstract: Panax notoginseng saponins (PNS) are active extracts obtained from the P. notoginseng plant. PNS exhibit various anti‑inflammatory, anti‑oxidant and anti‑aging pharmacological properties in some …
Panax notoginseng ameliorated albuminuria and podocyte epithelial-mesenchymal transition in diabetic rats.
PMID: Drug Des Devel Ther. 2020 ;14:527-538. Epub 2020 Feb 5. PMID: 32103895 Abstract Title: Panax Notoginseng Ameliorates Podocyte EMT by Targeting the Wnt/β-Catenin Signaling Pathway in STZ-Induced Diabetic Rats. Abstract: Introduction: Epithelial-mesenchymal transition (EMT) may contribute to podocyte dysfunction in diabetic nephropathy (DN). Aiming to identify novel therapeutic options, we investigated the protective effects …
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth.
PMID: J Biol Chem. 2020 Mar 13 ;295(11):3576-3589. Epub 2020 Feb 6. PMID: 32029476 Abstract Title: Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth. Abstract: It has been well-established that the deubiquitinating enzyme ubiquitin-specific peptidase 7 (USP7) supports cancer growth by up-regulating multiple cellular pathways, including Wnt/β-catenin signaling. Therefore, considerable …
Assessing the effects of parthenolide on inflammation, bone loss, and glial cells within a collagen antibody-induced arthritis model.
PMID: Mediators Inflamm. 2020 ;2020:6245798. Epub 2020 Mar 4. PMID: 32189995 Abstract Title: Assessing the Effects of Parthenolide on Inflammation, Bone Loss, and Glial Cells within a Collagen Antibody-Induced Arthritis Mouse Model. Abstract: Rheumatoid arthritis is characterised by a chronic inflammatory response resulting in destruction of the joint and significant pain. Although a range of …
Royal jelly accelerates healing of acetate induced gastric ulcers in male rats.
PMID: Gastroenterol Hepatol Bed Bench. 2020 ;13(1):14-22. PMID: 32190220 Abstract Title: Royal jelly accelerates healing of acetate induced gastric ulcers in male rats. Abstract: Aim: This study examined the healing potential of royal jelly on the acetic acid induced wounds healing in male rat's gastric mucosa.Background: Scientific reports suggest that, bee products can help in …
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