Quercetin-loaded nanoparticles enhance cytotoxicity and antioxidant activity on C6 glioma cells.

PMID:  Pharm Dev Technol. 2020 Mar 20:1-10. Epub 2020 Mar 20. PMID: 32192406 Abstract Title:  Quercetin-loaded nanoparticles enhance cytotoxicity and antioxidant activity on C6 glioma cells. Abstract:  Quercetin (Qu) is a natural flavonoid present in many commonly consumed food items. The dietary phytochemical quercetin prevents tumor proliferation and is a potent therapeutic cancer agent. The …

Quercetin lipid nanoparticles functionalized with transferrin for Alzheimer’s disease.

PMID:  Eur J Pharm Sci. 2020 Mar 18:105314. Epub 2020 Mar 18. PMID: 32200044 Abstract Title:  Quercetin lipid nanoparticles functionalized with transferrin for Alzheimer's disease. Abstract:  Quercetin was encapsulated in lipid nanoparticles (SLN and NLC) to take advantage of its neuroprotective properties in Alzheimer's disease. The nanoparticles were functionalized with transferrin to facilitate the passage …

Propolis affects Pseudomonas aeruginosa growth, biofilm formation, eDNA release and phenazine production.

PMID:  Microorganisms. 2020 Feb 12 ;8(2). Epub 2020 Feb 12. PMID: 32059431 Abstract Title:  Propolis AffectsGrowth, Biofilm Formation, eDNA Release and Phenazine Production: Potential Involvement of Polyphenols. Abstract:  () is an opportunistic pathogen responsible for a wide range of clinical conditions, from mild infections to life-threatening nosocomial biofilm-associated diseases, which are particularly severe in susceptible …

Caffeic acid phenethyl ester has a preventive effect on early brain injury after subarachnoid hemorrhage.

PMID:  World Neurosurg. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32200016 Abstract Title:  The Impact of Propolis Factor Caffeic Acid Phenethyl-Ester on the Cerebral Vasospasm and Early Brain Damage in the Exparimentally Induced Subarachnoid Hemorrhage on Rats. Abstract:  AIM: CAPE, a phenolic compound, besides being one of the biologically active components of propolis, is …

Effects of propolis and phenolic acids on triple-negative breast cancer cell lines.

PMID:  Molecules. 2020 Mar 12 ;25(6). Epub 2020 Mar 12. PMID: 32178333 Abstract Title:  Effects of Propolis and Phenolic Acids on Triple-Negative Breast Cancer Cell Lines: Potential Involvement of Epigenetic Mechanisms. Abstract:  Triple-negative breast cancer is an aggressive disease frequently associated with resistance to chemotherapy. Evidence supports that small molecules showing DNA methyltransferase inhibitory activity …

Propolis could be a chemopreventive agent against MNU-induced mammary carcinogenesis.

PMID:  Oxid Med Cell Longev. 2020 ;2020:4014838. Epub 2020 Feb 26. PMID: 32184916 Abstract Title:  Chemopreventive Effects of Propolis in the MNU-Induced Rat Mammary Tumor Model. Abstract:  Currently, one of the central problems in cancer management is the relapse of disease following conventional treatments, yet few therapeutic agents targeting resistance and tolerance exist. Propolis is …

Propolis and honey trigona decrease leptin levels of central obesity patients.

PMID:  Enferm Clin. 2020 Mar ;30 Suppl 2:96-99. PMID: 32204266 Abstract Title:  Propolis and honey trigona decrease leptin levels of central obesity patients. Abstract:  OBJECTIVE: This study aimed to examine whether honey and propolis Trigona can reduce the level of leptin in central obesity human.METHODS: It was a quasi-experimental study, population and sample were central …

hese findings suggest that the potent anti-inflammatory activity of T. officinale, possibly through the regulation of Nrf2/HO-1 and NF-κB signaling pathway.

PMID:  Am J Chin Med. 2020 Mar 5:1-18. Epub 2020 Mar 5. PMID: 32138531 Abstract Title:  Wigg. Attenuates Inflammatory Responses in Murine Microglia through the Nrf2/HO-1 and NF-B Signaling Pathways. Abstract:  As a long-established medicinal and edible homologous plant,Wigg. is widely distributed in Asia, Europe, and other parts of the world.is reported to exert a …

Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth.

PMID:  Phytother Res. 2020 Mar 6. Epub 2020 Mar 6. PMID: 32144852 Abstract Title:  Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth. Abstract:  Esophageal cancer (EC) is one of the leading causes to cancer death in the worldwide and major population of EC is esophageal squamous cell carcinoma (ESCC). Still, …

Licochalcone D induces ROS-dependent apoptosis in gefitinib-sensitive or resistant lung cancer cells.

PMID:  Biomolecules. 2020 Feb 13 ;10(2). Epub 2020 Feb 13. PMID: 32070026 Abstract Title:  Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET. Abstract:  Licochalcone D (LCD), a flavonoid isolated from a Chinese medicinal plant, has a variety of pharmacological activities. However, the anti-cancer effects of LCD …

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