PMID: Ann Clin Lab Sci. 2020 Jan ;50(1):65-72. PMID: 32161013 Abstract Title: Melatonin Inhibits TE-1 Esophageal Cancer Cells Metastasis by Suppressing the NF-κB Signaling Pathway and Decreasing MMP-9. Abstract: Melatonin is an amine hormone produced by mammals and the human pineal gland. Modern biomedical research has shown that melatonin has antitumor effects. However, the underlying …
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PMID: Pathol Res Pract. 2020 Mar 9:152919. Epub 2020 Mar 9. PMID: 32171553 Abstract Title: Targeting cancer stem cells by melatonin: Effective therapy for cancer treatment. Abstract: Melatonin is a physiological hormone produced by the pineal gland. In recent decades, enormous investigations showed that melatonin can prompt apoptosis in cancer cells and inhibit tumor metastasis …
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PMID: J Med Signals Sens. 2019 Oct-Dec;9(4):267-273. Epub 2019 Oct 24. PMID: 31737556 Abstract Title: Bromelain Inhibitory Effect on Colony Formation: AnStudy on Human AGS, PC3, and MCF7 Cancer Cells. Abstract: Bromelain is dotted with anticancer properties on various cancer cell lines. Anticancer pathways of bromelain, as well related intervening signalization are under investigation. Investigating …
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PMID: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419880258. PMID: 31752555 Abstract Title: Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo. Abstract: This study aimed to evaluate the antitumor enhancing effect of bromelain consumption on 4T1-challenged mice treated with cisplatin.Mice challenged with 4T1 triple-negative breast cancer cells received water, bromelain, cisplatin, or …
PMID: Korean J Pain. 2020 Jan 1 ;33(1):13-22. PMID: 31888313 Abstract Title: Antinociceptive and neuroprotective effects of bromelain in chronic constriction injury-induced neuropathic pain in Wistar rats. Abstract: Background: The continuous search for a novel neuropathic pain drug with few or no side effects has been a main focus of researchers for decades. This study …
PMID: Int Immunopharmacol. 2020 Mar 12 ;83:106365. Epub 2020 Mar 12. PMID: 32172204 Abstract Title: Melatonin prevents endothelial dysfunction in SLE by activating the nuclear receptor retinoic acid-related orphan receptor-α. Abstract: Atherosclerotic cardiovascular disease confers significant morbidity and mortality in patients with systemic lupus erythematosus (SLE). A substantial proportion of patients with SLE display accelerated …
PMID: Sci Rep. 2020 Mar 16 ;10(1):4790. Epub 2020 Mar 16. PMID: 32179814 Abstract Title: Usefulness of melatonin as complementary to chemotherapeutic agents at different stages of the angiogenic process. Abstract: Chemotherapeutics are sometimes administered with drugs, like antiangiogenic compounds, to increase their effectiveness. Melatonin exerts antitumoral actions through antiangiogenic actions. We studied if melatonin …
PMID: J Clin Invest. 2020 Mar 17. Epub 2020 Mar 17. PMID: 32182222 Abstract Title: Melatonin inhibits cytosolic mitochondrial-DNA induced neuroinflammatory signaling in accelerated aging and neurodegeneration. Abstract: Chronic inflammation is a pathologic feature of neurodegeneration and aging; however, the mechanism regulating this process is not understood. Melatonin, an endogenous free radical scavenger synthesized by …
PMID: Antioxidants (Basel). 2020 Mar 16 ;9(3). Epub 2020 Mar 16. PMID: 32187996 Abstract Title: Effects of Bisphenol A on Oxidative Stress in the Rat Brain. Abstract: We investigated the effect of bisphenol A (BPA) on oxidative stress and tau-related proteins in adult rat brains. BPA (10 mg/L) was administered to rats for eight weeks …
PMID: Mol Reprod Dev. 2020 Feb 28. Epub 2020 Feb 28. PMID: 32109339 Abstract Title: Neonatal exposure to bisphenol A advances pubertal development in female rats. Abstract: Neonatal exposure to bisphenol A (BPA) is hypothesized to advance pubertal development. However, the effects of neonatal BPA exposure on pubertal development has not been described. In this …
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