Taylor Mercado

Estrogen and bisphenol A in hypertension.

PMID: Curr Hypertens Rep. 2020 Feb 29 ;22(3):23. Epub 2020 Feb 29. PMID: 32114652 Abstract Title: Estrogen and Bisphenol A in Hypertension. Abstract: PURPOSE OF REVIEW: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This …

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Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway.

PMID: Sci Rep. 2020 Mar 6 ;10(1):4190. Epub 2020 Mar 6. PMID: 32144343 Abstract Title: Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Abstract: Epidemiological studies link long term exposure to xenoestrogen Bisphenol-A to adverse cardiovascular effects. Our previous results show that BPA induces hypertension by a mechanism involving CamKII activation …

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Notch pathway up-regulation via curcumin mitigates bisphenol-A (BPA) induced alterations in hippocampal oligodendrogenesis.

PMID: J Hazard Mater. 2020 Jan 8 ;392:122052. Epub 2020 Jan 8. PMID: 32151947 Abstract Title: Notch pathway up-regulation via curcumin mitigates bisphenol-A (BPA) induced alterations in hippocampal oligodendrogenesis. Abstract: CNS myelination process involves proliferation and differentiation of oligodendrocyte progenitor cells (OPCs). Defective myelination causes onset of neurological disorders. Bisphenol-A (BPA), a component of plastic …

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Lycopene alleviates disc degeneration under oxidative stress through the Nrf2 signaling pathway.

PMID: Mol Cell Probes. 2020 Mar 6:101559. Epub 2020 Mar 6. PMID: 32151764 Abstract Title: Lycopene alleviates disc degeneration under oxidative stress through the Nrf2 signaling pathway. Abstract: Intervertebral disc degeneration (IDD) is a main cause of diseases such as discogenic low back pain, cervical and lumbar disc herniation, degenerative spinal stenosis, and lumbar spondylolisthesis. …

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Lycopene alleviates DSS-induced colitis and behavioral disorders via mediating microbes-gut-brain axis balance.

PMID: J Agric Food Chem. 2020 Mar 12. Epub 2020 Mar 12. PMID: 32162923 Abstract Title: Lycopene alleviates DSS-induced colitis and behavioral disorders via mediating microbes-gut-brain axis balance. Abstract: Gut microbes play significant roles in colitis development. The current study was aimed to uncover the preventive effects of lycopene (LYC), a functional carotenoid component, on …

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Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A.

PMID: Hum Exp Toxicol. 2020 Mar 10:960327120909882. Epub 2020 Mar 10. PMID: 32153214 Abstract Title: Protective effects of lycopene on hippocampal neurotoxicity and memory impairment induced by bisphenol A in rats. Abstract: Bisphenol A (BPA) is used to produce polycarbonate plastic and epoxy resins which are used in many consumer products. Most people encounter BPA …

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Exercise training can attenuate the inflammatory milieu in women with systemic lupus erythematosus.

PMID: J Appl Physiol (1985). 2014 Sep 15 ;117(6):639-47. Epub 2014 Jul 18. PMID: 25038103 Abstract Title: Exercise training can attenuate the inflammatory milieu in women with systemic lupus erythematosus. Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by chronic inflammation. This study sought to assess the effects of an exercise training program …

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Physical exercise attenuates experimental autoimmune encephalomyelitis.

PMID: Mol Neurobiol. 2017 08 ;54(6):4723-4737. Epub 2016 Jul 22. PMID: 27447807 Abstract Title: Physical Exercise Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Peripheral Immune Response and Blood-Brain Barrier Disruption. Abstract: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) caused by demyelination, immune cell infiltration, and axonal damage. Herein, we …

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Aerobic training modulates T cell activation in elderly women with knee osteoarthritis.

PMID: Braz J Med Biol Res. 2016 ;49(11):e5181. Epub 2016 Nov 3. PMID: 27828665 Abstract Title: Aerobic training modulates T cell activation in elderly women with knee osteoarthritis. Abstract: Osteoarthritis of the knee (kOA) is a disease that mainly affects the elderly and can lead to major physical and functional limitations. However, the specific effects …

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Active subjects with autoimmune type 1 diabetes have better metabolic profiles than sedentary controls.

PMID: Cell Transplant. 2017 01 24 ;26(1):23-32. Epub 2016 Sep 20. PMID: 27983910 Abstract Title: Active Subjects With Autoimmune Type 1 Diabetes Have Better Metabolic Profiles Than Sedentary Controls. Abstract: Previous studies in humans with type 1 diabetes mellitus (T1D) and in nonobese diabetic mice have investigated the beneficial immunomodulatory potential of aerobic physical activity. …

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