Aged citrus peel (chenpi) extract causes dynamic alteration of colonic microbiota in high-fat diet induced obese mice.

PMID:  Food Funct. 2020 Mar 11. Epub 2020 Mar 11. PMID: 32159537 Abstract Title:  Aged citrus peel (chenpi) extract causes dynamic alteration of colonic microbiota in high-fat diet induced obese mice. Abstract:  Aged citrus peels (chenpi) have been used as a dietary supplement for gastrointestinal health maintenance in China. Recently, it was reported to exhibit …

Antioxidant and anti-inflammatory effects of Schisandra chinensis baillon hot water extract fermented using Lactobacilius paracasei.

PMID:  Food Sci Biotechnol. 2019 Dec ;28(6):1759-1767. Epub 2019 Jun 7. PMID: 31807348 Abstract Title:  Antioxidant and anti-inflammatory effects of an ethanol fraction from thebaillon hot water extract fermented usingsubsp. Abstract:  Waste management is a major part of the food industry. The present study was designed to utilize the discarded byproduct ofBaillon. The antioxidant and …

Lentil protein hydrolysate and a mixed training protocol is an efficient lifestyle intervention to manage cardiovascular and renal alterations in obesity.

PMID:  Eur J Nutr. 2020 Feb 6. Epub 2020 Feb 6. PMID: 32030473 Abstract Title:  The combined treatment with lentil protein hydrolysate and a mixed training protocol is an efficient lifestyle intervention to manage cardiovascular and renal alterations in obese Zucker rats. Abstract:  PURPOSE: Functional and structural changes in cardiovascular and renal systems resulting from …

Ginkgo biloba L. leaf extract may be able to improve the cognitive function in patients who suffered from mild dementia during long-term administration.

PMID:  Front Pharmacol. 2019 ;10:1688. Epub 2020 Feb 21. PMID: 32153388 Abstract Title:  An Updated Review of Randomized Clinical Trials Testing the Improvement of Cognitive Function ofExtract in Healthy People and Alzheimer's Patients. Abstract:  Alzheimer's disease (AD) is a common neurodegenerative disease, mainly manifested by cognitive dysfunction. It seriously reduces the quality of life, and …

Neuroprotective effects of urolithin A on H2O2-induced oxidative stress-mediated apoptosis in SK-N-MC cells.

PMID:  Nutr Res Pract. 2020 Feb ;14(1):3-11. Epub 2019 Oct 18. PMID: 32042368 Abstract Title:  Neuroprotective effects of urolithin A on HO-induced oxidative stress-mediated apoptosis in SK-N-MC cells. Abstract:  BACKGROUND/OBJECTIVES: Oxidative stress causes cell damage and death, which contribute to the pathogenesis of neurodegenerative diseases. Urolithin A (UA), a gut microbial-derived metabolite of ellagitannins and …

Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration.

PMID:  Free Radic Biol Med. 2020 Feb 24 ;150:109-119. Epub 2020 Feb 24. PMID: 32105828 Abstract Title:  Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway. Abstract:  Intervertebral disc degeneration (IDD) is a major cause of low back pain (LBP), and effective therapies are still lacking. Previous studies reported …

The metabolite urolithin-A ameliorates oxidative stress in neuro-2a cells.

PMID:  Antioxidants (Basel). 2020 Feb 21 ;9(2). Epub 2020 Feb 21. PMID: 32098107 Abstract Title:  The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent. Abstract:  Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries. The …

Protective effect of tanshinone IIA on H2O2-induced oxidative stress injury.

PMID:  J Recept Signal Transduct Res. 2020 Feb 26:1-9. Epub 2020 Feb 26. PMID: 32100629 Abstract Title:  Protective effect of tanshinone IIA on HO-induced oxidative stress injury in rat cardiomyocytes by activating Nrf2 pathway. Abstract:  To investigate the protective effect of tanshinone IIA on HO-induced oxidative stress injury in rat cardiomyocytes, and further to study …

Tanshinone IIA attenuates silica-induced pulmonary fibrosis.

PMID:  Chem Biol Interact. 2020 Mar 1 ;319:109024. Epub 2020 Feb 22. PMID: 32097614 Abstract Title:  Tanshinone IIA attenuates silica-induced pulmonary fibrosis via Nrf2-mediated inhibition of EMT and TGF-β1/Smad signaling. Abstract:  Silicosis is an occupational pulmonary fibrosis that is caused by inhalation of silica (SiO), and there are no effective drugs to treat this disease. …

These results suggest that tanshinone IIA protects against lung blast injury.

PMID:  Free Radic Biol Med. 2020 Mar 1. Epub 2020 Mar 1. PMID: 32131025 Abstract Title:  Tanshinone IIA alleviates blast-induced inflammation, oxidative stress and apoptosis in mice partly by inhibiting the PI3K/Akt/FoxO1 signaling pathway. Abstract:  Although Tanshinone IIA (Tan IIA) has been associated with inflammation, oxidative stress and apoptosis, the effects of Tan IIA on …

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