Gomisin A modulates aging progress via mitochondrial biogenesis in human diploid fibroblast cells.

PMID:  Clin Exp Pharmacol Physiol. 2018 06 ;45(6):547-555. Epub 2018 Feb 13. PMID: 29319901 Abstract Title:  Gomisin A modulates aging progress via mitochondrial biogenesis in human diploid fibroblast cells. Abstract:  Gomisin A from the fruit of Schisandra chinensis has many pharmacological properties, including hepato-protective, anti-diabetic, and anti-oxidative stress. However, the potential benefit of gomisin A …

Schisanhenol improves learning and memory in scopolamine-treated mice.

PMID:  Int J Neurosci. 2019 Feb ;129(2):110-118. Epub 2018 Oct 30. PMID: 30033800 Abstract Title:  Schisanhenol improves learning and memory in scopolamine-treated mice by reducing acetylcholinesterase activity and attenuating oxidative damage through SIRT1-PGC-1α-Tau signaling pathway. Abstract:  PURPOSE: Schisanhenol is a compound derived from the fruit of a traditional Chinese herb Schisandra rubriflora. The aim of …

Schisandrol B promotes liver regeneration after partial hepatectomy in mice.

PMID:  Eur J Pharmacol. 2018 Jan 5 ;818:96-102. Epub 2017 Oct 21. PMID: 29066412 Abstract Title:  Schisandrol B promotes liver regeneration after partial hepatectomy in mice. Abstract:  Liver regeneration is a vital process of recovery after liver damage, which is a promising clinical strategy after partial hepatectomy (PHx). Schisandrol B (SolB), one of the bioactive …

S. chinensis may find use as a complementary medicine in cyclophosphamide treatment.

PMID:  J Ethnopharmacol. 2018 Jan 10 ;210:223-231. Epub 2017 Aug 15. PMID: 28821392 Abstract Title:  Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Schisandra chinensis (Turcz.) Baill (S. chinensis) has been used for thousands years in China, and is usually applied in treatment …

Targeted lignan profiling and anti-inflammatory properties of Schisandra rubriflora and Schisandra chinensis extracts.

PMID:  Molecules. 2018 Nov 27 ;23(12). Epub 2018 Nov 27. PMID: 30486445 Abstract Title:  Targeted Lignan Profiling and Anti-Inflammatory Properties of Schisandra rubriflora and Schisandra chinensis Extracts. Abstract:  is a dioecious plant of increasing importance due to its lignan composition, and therefore, possible therapeutic properties. The aim of the work was lignan profiling of fruits, …

Gomisin A might be a potential novel therapeutic agent for metastatic colorectal cancer.

PMID:  Front Pharmacol. 2018 ;9:986. Epub 2018 Aug 29. PMID: 30210348 Abstract Title:  Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells. Abstract:  Gomisin A (G.A) is a dietary lignan compound from. In this study, the effect of G.A on the proliferation and metastasis of colorectal …

The results indicated that S. chinensis might be a candidate cosmetic preservative for its good antibacterial activity and multiple targets on E. coli.

PMID:  Curr Microbiol. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31938806 Abstract Title:  Antibacterial Effects of Schisandra chinensis Extract on Escherichia coli and its Applications in Cosmetic. Abstract:  Schisandra chinensis (Turcz.) Baill (S. chinensis), an edible traditional medicine herb, has a strong constitution, which extract has good antibacterial activity. The study investigated its antibacterial …

Schisantherin A causes endothelium-dependent and -independent vasorelaxation in isolated rat thoracic aorta.

PMID:  Life Sci. 2020 Mar 15 ;245:117357. Epub 2020 Jan 25. PMID: 31991180 Abstract Title:  Schisantherin A causes endothelium-dependent and -independent vasorelaxation in isolated rat thoracic aorta. Abstract:  AIMS: Schisandra is a good choice in Traditional Chinese Medicine for the therapy of cardiovascular diseases, but whether it contains a or some specific component (s) responsible …

Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus.

PMID:  J Chem Neuroanat. 2020 Feb 3 ;105:101751. Epub 2020 Feb 3. PMID: 32027950 Abstract Title:  Schisandrin A and B enhance the dentate gyrus neurogenesis in mouse hippocampus. Abstract:  Schisandrin A and B (Sch A and B) are the main effective components of Schisandra chinensis (S. chinensis), which is traditionally used to enhance mental and …

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