Author Archives: Taylor Mercado

PMID:  Biomed Pharmacother. 2018 May ;101:579-584. Epub 2018 Mar 22. PMID: 29514131 Abstract Title:  Potential of resveratrol in mitigating metabolic disturbances induced by ethanol. Abstract:  Alcohol abuse is associated with numerous health problems, including metabolic disturbances and liver damage. Therefore, different compounds are continuously being tested to evaluate their potential effectiveness in reducing these harmful …

Continue reading “Resveratrol mitigates some, but not all consequences of ethanol consumption.”

PMID:  Inflammopharmacology. 2019 Jun ;27(3):549-559. Epub 2018 Aug 1. PMID: 30069718 Abstract Title:  Inhibition of adiposity and related metabolic disturbances by polyphenol-rich extract of Boswellia serrata gum through alteration of adipo/cytokine profiles. Abstract:  BACKGROUND: The role of proinflammatory cytokines in adiposity is well established. The anti-inflammatory and antihyperglycemia effects of Boswellia serrata (B. Serrata) gum …

Continue reading “Boswellia is as effective as orlistat in preventing obesity, hyperlipidemia, steatosis, and insulin resistance through anti-inflammatory effects and upregulation of adiponectin.”

PMID:  Molecules. 2019 Apr 3 ;24(7). Epub 2019 Apr 3. PMID: 30987086 Abstract Title:  Resveratrol and Quercetin Administration Improves Antioxidant DEFENSES and reduces Fatty Liver in Metabolic Syndrome Rats. Abstract:  Mixtures of resveratrol (RSV) + quercetin (QRC) have antioxidant properties that probably impact on fatty liver in metabolic syndrome (MS) individuals. Here, we study the …

Continue reading “Resveratrol and quercetin reduces fatty liver through by enhancing antioxidant capacity.”

PMID:  Foods. 2019 Aug 8 ;8(8). Epub 2019 Aug 8. PMID: 31398785 Abstract Title:  Elderberry (L.) Fruit Extract Alleviates Oxidative Stress, Insulin Resistance, and Inflammation in Hypertrophied 3T3-L1 Adipocytes and Activated RAW 264.7 Macrophages. Abstract:  Oxidative stress and inflammation in hypertrophied adipose tissue with excessive fat accumulation play a crucial role in the development of …

Continue reading “Elderberry ameliorates oxidative stress, insulin resistance, and inflammation in vitro.”

PMID:  J Agric Food Chem. 2019 Dec 11 ;67(49):13605-13616. Epub 2019 Dec 2. PMID: 31735033 Abstract Title:  Resveratrol and Oxyresveratrol Activate Thermogenesis via Different Transcriptional Coactivators in High-Fat Diet-Induced Obese Mice. Abstract:  Obesity is a global public health issue. Thermogenesis is a novel way to promote anti-obesity by consuming energy as heat rather than storing …

Continue reading “Resveratrol and oxyresveratrol activate thermogenesis via different transcriptional coactivators in high-fat diet-induced obese mice.”

PMID:  Adv Ther. 2020 Mar 4. Epub 2020 Mar 4. PMID: 32130662 Abstract Title:  Current Perspectives on Gut Microbiome Dysbiosis and Depression. Abstract:  The human gut microbiome partakes in a bidirectional communication pathway with the central nervous system (CNS), named the microbiota-gut-brain axis. The microbiota-gut-brain axis is believed to modulate various central processes through the …

Continue reading “Current perspectives on gut microbiome dysbiosis and depression.”

PMID:  Cell Rep. 2020 Mar 3 ;30(9):2934-2947.e6. PMID: 32130898 Abstract Title:  Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production. Abstract:  Secondary bacterial infections often complicate viral respiratory infections. We hypothesize that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor respiratory bacterial superinfection. Sublethal …

Continue reading “Gut dysbiosis during influenza contributes to pulmonary pneumococcal super-infection through altered short-chain fatty acid production.”

PMID:  Pathogens. 2020 Feb 12 ;9(2). Epub 2020 Feb 12. PMID: 32059467 Abstract Title:  Chrysin-Loaded Chitosan Nanoparticles Potentiates Antibiofilm Activity against. Abstract:  The application of nanotechnology in medicine is gaining popularity due to its ability to increase the bioavailability and biosorption of numerous drugs. Chrysin, a flavone constituent ofis well-reported for its biological properties. However, …

Continue reading “Chrysin-loaded chitosan nanoparticles potentiates antibiofilm activity against Staphylococcus aureus.”

PMID:  Sci Rep. 2020 Feb 19 ;10(1):2932. Epub 2020 Feb 19. PMID: 32076123 Abstract Title:  Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides. Abstract:  Psoriasis is a common non-contagious chronic inflammatory skin lesion, with frequent recurrence. It mainly occurs due to aberrant regulation of the immune system leading …

Continue reading “Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides.”

PMID:  Antioxidants (Basel). 2020 Feb 16 ;9(2). Epub 2020 Feb 16. PMID: 32079112 Abstract Title:  Chrysin Reduces Oxidative Stress but Does Not Affect Polyol Pathway in the Lenses of Type 1 Diabetic Rats. Abstract:  Prolonged hyperglycemia is one of the main causes of reactive oxygen species and free radicals generation in diabetes which may affect …

Continue reading “Chrysin reduces oxidative stress in the lenses of type 1 diabetic rats.”