PMID: Environ Sci Pollut Res Int. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32030592 Abstract Title: Protective effect of alpha-lipoic acid on di-(2-ethylhexyl) phthalate-induced testicular toxicity in mice. Abstract: Phthalates are synthetic chemicals, widely used as plasticizers due to their flexibility in plastics. Human populations may be exposed to phthalates through direct contact or …
Author Archives: Taylor Mercado
Time course of phthalate cumulative risks to male developmental health over a 27-year period.
PMID: Environ Int. 2020 Feb 5 ;137:105467. Epub 2020 Feb 5. PMID: 32036120 Abstract Title: Time course of phthalate cumulative risks to male developmental health over a 27-year period: Biomonitoring samples of the German Environmental Specimen Bank. Abstract: In several human biomonitoring surveys, changes in the usage patterns of phthalates have come to light, but …
Embryonic exposures to mono-2-ethylhexyl phthalate induce larval steatosis in zebrafish independent of Nrf2a signaling.
PMID: J Dev Orig Health Dis. 2020 Feb 17:1-9. Epub 2020 Feb 17. PMID: 32063256 Abstract Title: Embryonic exposures to mono-2-ethylhexyl phthalate induce larval steatosis in zebrafish independent of Nrf2a signaling. Abstract: Mono-2-ethylhexyl phthalate (MEHP) is the primary metabolite of the ubiquitous plasticizer and toxicant, di-2-ethylhexyl phthalate. MEHP exposure has been linked to abnormal development, …
Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents.
PMID: Environ Pollut. 2020 Feb 14 ;261:114164. Epub 2020 Feb 14. PMID: 32088434 Abstract Title: Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents. Abstract: Di-(2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer, which can enter the body through a variety of ways and exerted multiple …
Association of phthalate exposure with precocious and delayed pubertal timing in girls and boys.
PMID: Environ Sci Process Impacts. 2020 Feb 24. Epub 2020 Feb 24. PMID: 32091510 Abstract Title: Association of phthalate exposure with precocious and delayed pubertal timing in girls and boys: a systematic review and meta-analysis. Abstract: Exposure to phthalate derivatives has adverse effects on the health and development of humans, especially for children. A growing …
Prenatal exposure to a phthalate mixture leads to multigenerational and transgenerational effects on uterine morphology and function in mice.
PMID: Reprod Toxicol. 2020 Feb 29. Epub 2020 Feb 29. PMID: 32126281 Abstract Title: Prenatal Exposure to a Phthalate Mixture Leads to Multigenerational and Transgenerational Effects on Uterine Morphology and Function in Mice. Abstract: Phthalates are commonly used plasticizers and additives that are found in plastic containers, children's toys and medical equipment. Phthalates are classified …
Long-term dietary administration of diethyl phthalate triggers loss of insulin sensitivity in two key insulin target tissues of mice.
PMID: Hum Exp Toxicol. 2020 Mar 4:960327120909526. Epub 2020 Mar 4. PMID: 32129097 Abstract Title: Long-term dietary administration of diethyl phthalate triggers loss of insulin sensitivity in two key insulin target tissues of mice. Abstract: Over the past years, a growing body of work has linked numerous pervasive environmental chemicals with a multitude of adverse …
Phthalate exposures and MicroRNA expression in uterine fibroids.
PMID: Epigenet Insights. 2020 ;13:2516865720904057. Epub 2020 Feb 18. PMID: 32128507 Abstract Title: Phthalate Exposures and MicroRNA Expression in Uterine Fibroids: The FORGE Study. Abstract: Phthalates are associated with multiple, adverse reproductive outcomes including increased risk of uterine leiomyoma (fibroids). Phthalates can interact with epigenetic modifications including microRNAs (miRNAs), which help regulate processes crucial to …
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Effect of bisphenol A on human neutrophils immunophenotype.
PMID: Sci Rep. 2020 Feb 20 ;10(1):3083. Epub 2020 Feb 20. PMID: 32080224 Abstract Title: Effect of bisphenol A on human neutrophils immunophenotype. Abstract: Neutrophils (PMN) play a key role in eliciting congenital immune response. These cells are equipped with specific receptors that are located on the surface of their cell membrane. These receptors produce …
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Protein kinase D1 (PKD1) is a new functional non-genomic target of bisphenol A in breast cancer cells.
PMID: Front Pharmacol. 2019 ;10:1683. Epub 2020 Jan 31. PMID: 32082170 Abstract Title: Protein Kinase D1 (PKD1) Is a New Functional Non-Genomic Target of Bisphenol A in Breast Cancer Cells. Abstract: Exposure to bisphenol A (BPA), one of the most widespread endocrine disruptors present in our environment, has been associated with the recent increased prevalence …
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