PMID: Br J Sports Med. 2019 Nov 4. Epub 2019 Nov 4. PMID: 31685526 Abstract Title: Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis. Abstract: OBJECTIVE: To investigate the association of running participation and the dose of running with …
Author Archives: Taylor Mercado
The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain.
PMID: Appl Physiol Nutr Metab. 2019 Dec ;44(12):1267-1275. Epub 2019 Nov 6. PMID: 31691583 Abstract Title: The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain. Abstract: Parkinson's disease is characterized by neurodegeneration and learning deficiency. Physical exercise can alleviate these symptoms by increasing the expression of some effective and relevant factors. The …
Exercise-induced changes of gene expression in the cerebellum of aged mice.
PMID: Biochem Biophys Res Commun. 2020 Jan 22 ;521(4):952-956. Epub 2019 Nov 11. PMID: 31718796 Abstract Title: Exercise-induced changes of gene expression in the cerebellum of aged mice. Abstract: PURPOSE: Exercise has been prescribed to the elderly based on its effect on increasing muscle strength and protein synthesis that prevent sense of balance and/or cognitive …
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Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity.
PMID: Learn Mem. 2019 Dec ;26(12):485-492. Epub 2019 Nov 15. PMID: 31732709 Abstract Title: Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity. Abstract: The beneficial effects of exercise on cognition are well established; however specific exercise parameters regarding the frequency and duration of physical activity that provide optimal cognitive health …
Physical exercise mitigates behavioral impairments in a rat model of sporadic Alzheimer’s disease.
PMID: Behav Brain Res. 2020 Feb 3 ;379:112358. Epub 2019 Nov 13. PMID: 31733314 Abstract Title: Physical exercise mitigates behavioral impairments in a rat model of sporadic Alzheimer's disease. Abstract: Physical exercise has proven to be beneficial to mitigate several deleterious effects associated with neurodegenerative diseases, including Alzheimer's Disease (AD). Here, we investigated the role …
These results suggest that TRX-1-mediated hippocampal neurogenesis by β2-AR function is a potential mechanism underlying the psychotropic effect of exercise.
PMID: J Exerc Nutrition Biochem. 2019 Sep 30 ;23(3):13-21. PMID: 31743979 Abstract Title: Neurogenic effect of exercise via the thioredoxin-1/ extracellular regulated kinase/β-catenin signaling pathway mediated by β2-adrenergic receptors in chronically stressed dentate gyrus. Abstract: PURPOSE: Chronic stress is a precipitating factor for depression, whereas exercise is beneficial for both the mood and cognitive process. …
Chronic exercise modulates the cellular immunity and its cannabinoid receptors expression.
PMID: PLoS One. 2019 ;14(11):e0220542. Epub 2019 Nov 18. PMID: 31738771 Abstract Title: Chronic exercise modulates the cellular immunity and its cannabinoid receptors expression. Abstract: The impact of performing exercise on the immune system presents contrasting effects on health when performed at different intensities. In addition, the consequences of performing chronic exercise have not been …
Treadmill exercise rescues mitochondrial function and motor behavior in the CAG140 knock-in mouse model of Huntington’s disease.
PMID: Chem Biol Interact. 2020 Jan 5 ;315:108907. Epub 2019 Nov 26. PMID: 31778667 Abstract Title: Treadmill exercise rescues mitochondrial function and motor behavior in the CAGknock-in mouse model of Huntington's disease. Abstract: BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by polyglutamine (CAG) expansion in the Huntingtin (HTT) gene. The CAGknock-in …
Endurance running exercise is an effective alternative to estradiol replacement for restoring hyperglycemia.
PMID: J Physiol Sci. 2019 Nov ;69(6):1029-1040. Epub 2019 Nov 28. PMID: 31782092 Abstract Title: Endurance running exercise is an effective alternative to estradiol replacement for restoring hyperglycemia through TBC1D1/GLUT4 pathway in skeletal muscle of ovariectomized rats. Abstract: Menopause is a risk factor for impaired glucose metabolism. Alternative treatment of estrogen for postmenopausal women is …
Voluntary wheel running reduces amyloid-β42 and rescues behaviour in aged Tg2576 mouse model of Alzheimer’s disease.
PMID: J Alzheimers Dis. 2020 ;73(1):359-374. PMID: 31796673 Abstract Title: Voluntary Wheel Running Reduces Amyloid-β42 and Rescues Behavior in Aged Tg2576 Mouse Model of Alzheimer's Disease. Abstract: Exercise has been shown to be protective against the risk of dementias, including Alzheimer's disease (AD). Intervention studies have demonstrated its ability to mitigate cognitive and behavioral impairments …
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