A case series of beneficial clinical outcomes associated with manual lumbar spine therapy in complex regional pain syndrome.

PMID:  Physiother Theory Pract. 2020 Jan ;36(1):241-248. Epub 2018 Jun 6. PMID: 29873592 Abstract Title:  Utilization of manual therapy to the lumbar spine in conjunction with traditional conservative care for individuals with bilateral lower extremity complex regional pain syndrome: A case series. Abstract:  : Conservative therapies for complex regional pain syndrome (CRPS) have traditionally focused …

This paper argues for a role of vitamin K in complex regional pain syndrome.

PMID:  Med Hypotheses. 2010 Sep ;75(3):319-23. Epub 2010 Apr 7. PMID: 20378261 Abstract Title:  Complex regional pain syndrome: a vitamin K dependent entity? Abstract:  Complex regional pain syndrome (CRPS) is the complication of some injuries, such as a fracture, which affects the distal end of the injured extremity characterized by pain, allodynia, hyperalgesia, edema, abnormal …

This paper argues for the role of neuroinflammation in migraines and a connection between migraines and complex regional pain syndrome.

PMID:  Pain Pract. 2011 Mar-Apr;11(2):199-200. PMID: 21371256 Abstract Title:  Is migraine a complex regional pain syndrome of the brain? Migraine prophylaxis with vitamin C? Abstract:  [n/a] read more

Vitamin C prevents complex regional pain syndrome in foot and ankle surgery.

PMID:  Foot Ankle Surg. 2009 ;15(4):179-82. Epub 2009 Apr 5. PMID: 19840748 Abstract Title:  Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery. Abstract:  BACKGROUND: The public health cost impact of complex regional pain syndrome type I (CRPS I) is considerable in both emergency and scheduled …

Oxidative stress contributes to fracture/cast-induced inflammation and pain in a rat model of complex regional pain syndrome.

PMID:  J Pain. 2018 10 ;19(10):1147-1156. Epub 2018 Apr 30. PMID: 29715519 Abstract Title:  Oxidative Stress Contributes to Fracture/Cast-Induced Inflammation and Pain in a Rat Model of Complex Regional Pain Syndrome. Abstract:  : Clinical evidence suggests that vitamin C (Vit C) may protect against the development of complex regional pain syndrome (CRPS) after fracture or …

This study shows that there are marked differences in plasma amino acids between controls and complex regional pain syndrome type 1.

PMID:  Acta Anaesthesiol Scand. 2008 May ;52(5):688-94. PMID: 18419723 Abstract Title:  Increased plasma glutamate, glycine, and arginine levels in complex regional pain syndrome type 1. Abstract:  BACKGROUND: Various inflammatory mediators have been identified as potential contributors to complex regional pain syndrome type 1 (CRPS1), but these mediators do not entirely explain certain manifestations of the …

Electroacupuncture induces antihyperalgesic effect through endothelin-B receptor in the chronic phase of a mouse model of complex regional pain syndrome type I.

PMID:  Pflugers Arch. 2018 12 ;470(12):1815-1827. Epub 2018 Aug 10. PMID: 30094478 Abstract Title:  Electroacupuncture induces antihyperalgesic effect through endothelin-B receptor in the chronic phase of a mouse model of complex regional pain syndrome type I. Abstract:  Complex regional pain syndrome (CRPS) is a disorder that involves abnormal inflammation and nerve dysfunction frequently resistant to …

This small case series suggests that HF10-SCS may be a viable option for patients with complex regional pain syndrome who have chronic intractable pain, including those who had suboptimal results from traditional spinal cord stimulation.

PMID:  Pain Pract. 2019 03 ;19(3):289-294. Epub 2019 Jan 7. PMID: 30365222 Abstract Title:  High-Frequency Spinal Cord Stimulation at 10 kHz for the Treatment of Complex Regional Pain Syndrome: A Case Series of Patients With or Without Previous Spinal Cord Stimulator Implantation. Abstract:  BACKGROUND: High-frequency spinal cord stimulation at 10 kHz (HF10-SCS) has been demonstrated …

This review concludes that ozone therapy is a novel, safe, and inexpensive approach for reflex sympathetic dystrophy/complex regional pain syndrome, and an alternative to drugs.

PMID:  Curr Pain Headache Rep. 2019 May 6 ;23(6):41. Epub 2019 May 6. PMID: 31062104 Abstract Title:  Ozone Therapy for Complex Regional Pain Syndrome: Review and Case Report. Abstract:  PURPOSE OF REVIEW: The world faces a crisis in pain management. CRPS is a multifaceted painful disorder, which is difficult to treat and resolve. Ozone therapy …

Blockage of the TRPV1 channel may ameliorate complex regional pain syndrome type 1.

PMID:  Front Pharmacol. 2019 ;10:453. Epub 2019 Apr 26. PMID: 31105572 Abstract Title:  TRPV1 Channel Contributes to the Behavioral Hypersensitivity in a Rat Model of Complex Regional Pain Syndrome Type 1. Abstract:  Complex regional pain syndrome type 1 (CRPS-I) is a debilitating pain condition that significantly affects life quality of patients. It remains a clinically …

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