PMID: J Cancer. 2019 ;10(23):5843-5851. Epub 2019 Oct 6. PMID: 31737120 Abstract Title: Cucurbitacin E inhibits cellular proliferation and enhances the chemo-response in gastric cancer by suppressing AKt activation. Abstract: The incidence and mortality rate of gastric cancer has markedly declined over the past few decades, due to the progress and advances in the development …
Author Archives: Taylor Mercado
Cucurbitacin E inhibits Huh7 hepatoma carcinoma cell Proliferation and metastasis.
PMID: Molecules. 2020 Jan 28 ;25(3). Epub 2020 Jan 28. PMID: 32012950 Abstract Title: Cucurbitacin E Inhibits Huh7 Hepatoma Carcinoma Cell Proliferation and Metastasis via Suppressing MAPKs and JAK/STAT3 Pathways. Abstract: Cucurbitacin E (CuE), a highly oxygenated tetracyclic triterpene from Cucurbitaceae, has shown to exhibit potent cytotoxic and anti-proliferative properties against several human cancer cells. …
Novel mechanistic insight into the anticancer activity of cucurbitacin D against pancreatic cancer.
PMID: Cells. 2019 Dec 31 ;9(1). Epub 2019 Dec 31. PMID: 31906106 Abstract Title: Novel Mechanistic Insight into the Anticancer Activity of Cucurbitacin D against Pancreatic Cancer (Cuc D Attenuates Pancreatic Cancer). Abstract: Pancreatic cancer (PanCa) is one of the leading causes of death from cancer in the United States. The current standard treatment for …
A review of the role of phytochemicals in cancer prevention.
PMID: Int J Mol Sci. 2019 Oct 9 ;20(20). Epub 2019 Oct 9. PMID: 31600949 Abstract Title: Role of Phytochemicals in Cancer Prevention. Abstract: The use of synthetic, natural, or biological agents to minimize the occurrence of cancer in healthy individuals is defined as cancer chemoprevention. Chemopreventive agents inhibit the development of cancer either by …
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Suboptimal zinc and selenium intake and serum concentration deficiencies are highly prevalent in treated HIV-positive individuals.
PMID: Nutrition. 2020 Feb ;70:110585. Epub 2019 Sep 13. PMID: 31698296 Abstract Title: Zinc and selenium indicators and their relation to immunologic and metabolic parameters in male patients with human immunodeficiency virus. Abstract: OBJECTIVES: Micronutrient deficiencies are common among people living with HIV (PLWHIV). The clinical and immunologic consequences of micronutrient deficiencies have been poorly …
Evidence for a manifold role of selenium in infertility.
PMID: Hormones (Athens). 2020 Mar ;19(1):55-59. Epub 2019 Nov 7. PMID: 31701489 Abstract Title: Evidence for a manifold role of selenium in infertility. Abstract: This review aimed to assess the evidence from observational and interventional studies in humans and animals regarding the role of selenium (Se) in male and female infertility. As oxidative stress can …
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The findings showed that selenium supplementation might reduce oxidative stress.
PMID: Hormones (Athens). 2019 Dec ;18(4):451-462. Epub 2019 Dec 10. PMID: 31820398 Abstract Title: Effect of selenium supplementation on antioxidant markers: a systematic review and meta-analysis of randomized controlled trials. Abstract: AIM: The aim of this study is the systematic review and meta-analysis of controlled trial studies to assess the antioxidant effects of selenium (Se) …
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The current analysis shows the influence of life factors on prostate health benefits of supplemental selenium.
PMID: Nutrients. 2019 Dec 18 ;12(1). Epub 2019 Dec 18. PMID: 31861307 Abstract Title: Selenium Supplementation and Prostate Health in a New Zealand Cohort. Abstract: BACKGROUND: There is variable reporting on the benefits of a 200μg/d selenium supplementation towards reducing prostate cancer impacts. The current analysis is to understand whether stratified groups receive supplementation benefits …
These data highlight the potential beneficial effect of selenomethionine supplementation as a therapeutic strategy for atherosclerosis.
PMID: Redox Biol. 2020 Jan ;29:101409. Epub 2019 Dec 16. PMID: 31926617 Abstract Title: Selenomethionine supplementation reduces lesion burden, improves vessel function and modulates the inflammatory response within the setting of atherosclerosis. Abstract: Atherosclerosis is a chronic inflammatory disease of the vasculature characterised by the infiltration of activated neutrophils and macrophages at sites of damage …
Selenium mitigates cadmium toxicity by preventing oxidative stress and enhancing photosynthesis and micronutrient availability on radish.
PMID: Environ Sci Pollut Res Int. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31997246 Abstract Title: Selenium mitigates cadmium toxicity by preventing oxidative stress and enhancing photosynthesis and micronutrient availability on radish (Raphanus sativus L.) cv. Cherry Belle. Abstract: We aimed to examine the effects of selenium on the tolerance of radish plants CV. …
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