PMID: Avicenna J Phytomed. 2020 Jan-Feb;10(1):11-23. PMID: 31921604 Abstract Title: Molecular mechanisms underlying gallic acid effects against cardiovascular diseases: An update review. Abstract: Objective: The prevalence of cardiovascular diseases (CVDs) is growing. CVDs are the major cause of mortality and have become one of the most important health challenges in developing countries. Gallic acid (GA) …
Author Archives: Taylor Mercado
Gallic acid prevents 1, 2-Dimethylhydrazine induced colon inflammation, toxicity, mucin depletion, and goblet cell disintegration.
PMID: Environ Toxicol. 2020 Jan 11. Epub 2020 Jan 11. PMID: 31925992 Abstract Title: Gallic acid prevents 1, 2-Dimethylhydrazine induced colon inflammation, toxicity, mucin depletion, and goblet cell disintegration. Abstract: 1,2-Dimethylhydrazine (DMH), an environmental toxicant specifically targets the colon. The present study was aimed to evaluate the efficacy of gallic acid (GA) against colon toxicity …
Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor.
PMID: Sci Rep. 2020 Jan 29 ;10(1):1403. Epub 2020 Jan 29. PMID: 31996731 Abstract Title: Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor. Abstract: This study investigated the inhibitory effect of arctigenin, a novel anti-inflammatory lignan, on prostate cancer in obese conditions both in vitro …
Anti‑metastatic effects of arctigenin are regulated by MAPK/AP‑1 signaling in 4T‑1 mouse breast cancer cells.
PMID: Mol Med Rep. 2020 Mar ;21(3):1374-1382. Epub 2020 Jan 13. PMID: 32016480 Abstract Title: Anti‑metastatic effects of arctigenin are regulated by MAPK/AP‑1 signaling in 4T‑1 mouse breast cancer cells. Abstract: Arctigenin is a natural lignan that is found in burdock with anti‑viral, ‑oxidative, ‑inflammatory and anti‑tumor activities. In the current study, the effect of …
Evaluation of cytotoxicity, cell cycle arrest and apoptosis induced by Anethum graveolens L. essential oil in human hepatocellular carcinoma cell line.
PMID: Saudi Pharm J. 2019 Nov ;27(7):1053-1060. Epub 2019 Sep 25. PMID: 31997913 Abstract Title: Evaluation of cytotoxicity, cell cycle arrest and apoptosis induced byLessential oil in human hepatocellular carcinoma cell line. Abstract: L. () commonly known as, is an essential oil bearing plant extensively being used in traditional system of medicine. However, the reports …
Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis.
PMID: Mol Cell Biochem. 2020 Feb 17. Epub 2020 Feb 17. PMID: 32065351 Abstract Title: Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis. Abstract: Arctigenin, a mitochondrial complex I inhibitor, has been identified as a potential anti-tumor agent, but the involved mechanism still remains elusive. Herein, we …
Arctigenin prevents the progression of osteoarthritis.
PMID: J Cell Mol Med. 2020 Feb 24. Epub 2020 Feb 24. PMID: 32090454 Abstract Title: Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB axis: In vitro and in vivo studies. Abstract: Osteoarthritis (OA), which is principally featured by progressive joint metabolic imbalance and subsequent degeneration of articular cartilage, is a common chronic joint …
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Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy.
PMID: Pharmacol Res. 2020 Feb 22:104721. Epub 2020 Feb 22. PMID: 32097750 Abstract Title: Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy. Abstract: TMEM16A plays critical roles in physiological process and may serve as drug targets for diverse diseases. In recently, it has started to be regarded as potential primary lung adenocarcinoma targets. Here, …
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Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts.
PMID: Int Immunopharmacol. 2020 Feb 18 ;82:106302. Epub 2020 Feb 18. PMID: 32086097 Abstract Title: Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts via the TLR4/NF-κB and TNFR1/NF-κB signaling pathways. Abstract: Toxoplasma gondii (T. gondii) is a known neurotropic protozoan that remains in the central nervous system and induces neuropsychiatric diseases in intermediate hosts. …
Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis.
PMID: Postgrad Med J. 2020 Feb 3. Epub 2020 Feb 3. PMID: 32015189 Abstract Title: Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis. Abstract: Obesity is a growing chronic health problem worldwide. Studies about acupuncture for obesity treatment are many. But there are some doubts about the effectiveness of acupuncture versus …
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