Prebiotic-resistant starch supplementation seems to be a promising nutritional strategy to improve inflammation, oxidative stress and to reduce indoxyl sulfate plasma levels in chronic kidney disease patients on hemodialysis.

PMID:  Food Funct. 2018 Dec 13 ;9(12):6508-6516. PMID: 30468238 Abstract Title:  Could resistant starch supplementation improve inflammatory and oxidative stress biomarkers and uremic toxins levels in hemodialysis patients? A pilot randomized controlled trial. Abstract:  An imbalance of gut microbiota is considered a new cardiovascular risk factor for chronic kidney disease (CKD) patients, since it is …

Glycyrrhizic acid protects against non-alcoholic fatty liver disease in mice due to regulation of genes involved in lipid, glucose homeostasis and insulin sensitivity.

PMID:  Eur J Pharmacol. 2017 Jul 5 ;806:75-82. Epub 2017 Apr 14. PMID: 28414056 Abstract Title:  Protective effects of glycyrrhizic acid against non-alcoholic fatty liver disease in mice. Abstract:  Non-alcoholic fatty liver disease (NAFLD) has become a predictive factor of death from many diseases. The purpose of the present study is to investigate the protective …

Beta-glucan and mulberry have synergistic effects on metabolic disorders.

PMID:  Nutrients. 2017 Oct 12 ;9(10). Epub 2017 Oct 12. PMID: 29023387 Abstract Title:  Combination ofβ-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet. Abstract:  β-glucan (BG) and mulberry have received increasing attention for their benefits as natural sources of metabolic health. In the current study, we investigated …

Quercetin, a pneumolysin inhibitor, protects mice against Streptococcus pneumoniae infection.

PMID:  Microb Pathog. 2020 Mar ;140:103934. Epub 2019 Dec 17. PMID: 31862394 Abstract Title:  Quercetin, a pneumolysin inhibitor, protects mice against Streptococcus pneumoniae infection. Abstract:  Pneumolysin (PLY), a pore-forming cytotoxin and a major virulence determinant, is a member of the cholesterol-dependent cytolysin (CDC) family and essential for promoting Streptococcus pneumoniae (S.pneumoniae) infection. Due to the …

Starch and β-glucan in a whole grain-like structural form have the potential as a dietary strategy to combat obesity-induced hepatic insulin resistance for improved health.

PMID:  Food Funct. 2019 Aug 1 ;10(8):5091-5101. Epub 2019 Jul 31. PMID: 31363728 Abstract Title:  Starch andβ-glucan in a whole-grain-like structural form improve hepatic insulin sensitivity in diet-induced obese mice. Abstract:  Whole-grain food (WGF) is well known for its anti-diabetic effect, and alleviation of obesity-induced insulin resistance (IR) might be one of the underlying mechanisms. …

Barley and beta-glucan isolated from barley lower total and LDL cholesterol.

n/a PMID:  Eur J Clin Nutr. 2010 Dec ;64(12):1472-80. Epub 2010 Oct 6. PMID: 20924392 Abstract Title:  β-glucan from barley and its lipid-lowering capacity: a meta-analysis of randomized, controlled trials. Abstract:  BACKGROUND/OBJECTIVES: To more precisely quantify the effect of barleyβ-glucan on blood lipid concentrations in humans and to examine the factors that could affect its …

Studies show that, on average, oat consumption is associated with 5% and 7% reductions in total and LDL cholesterol, respectively.

PMID:  Nutr Rev. 2011 Jun ;69(6):299-309. PMID: 21631511 Abstract Title:  Cholesterol-lowering effects of oatβ-glucan. Abstract:  Elevated total and low-density lipoprotein (LDL) cholesterol levels are considered major risk factors for cardiovascular disease. Oatβ-glucan, a soluble dietary fiber that is found in the endosperm cell walls of oats, has generated considerable interest due to its cholesterol-lowering properties. …

Quercetin protects the vascular endothelium against iron overload damages.

PMID:  Eur J Pharmacol. 2020 Feb 5 ;868:172885. Epub 2019 Dec 20. PMID: 31870832 Abstract Title:  Quercetin protects the vascular endothelium against iron overload damages via ROS/ADMA/DDAHⅡ/eNOS/NO pathway. Abstract:  The aberrant accumulation of iron causes vascular endothelium damage, which is thought to be associated with excess reactive oxygen species (ROS) generation. Quercetin (Que), as a …

Quercetin modulates hyperglycemia by improving the pancreatic antioxidant status and enzymes activities linked with glucose metabolism.

PMID:  J Food Biochem. 2020 Feb ;44(2):e13127. Epub 2019 Dec 26. PMID: 31876980 Abstract Title:  Quercetin modulates hyperglycemia by improving the pancreatic antioxidant status and enzymes activities linked with glucose metabolism in type 2 diabetes model of rats: In silico studies of molecular interaction of quercetin with hexokinase and catalase. Abstract:  Quercetin was assessed for …

β-glucans reduce LDL cholesterol in patients with myasthenia gravis.

PMID:  Eur J Clin Nutr. 2013 Feb ;67(2):226-7. Epub 2012 Nov 28. PMID: 23187951 Abstract Title:  β-glucans reduce LDL cholesterol in patients with myasthenia gravis. Abstract:  We aimed at evaluating whetherβ-glucans could improve low-density lipoprotein (LDL) cholesterol levels and/or glycemic control in patients with myasthenia gravis (MG), in whom statins usually have muscle-related side effects. …

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