PMID: Sci Rep. 2017 09 6 ;7(1):10593. Epub 2017 Sep 6. PMID: 28878220 Abstract Title: Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors. Abstract: Bovine lactoferrin is a biglobular multifunctional iron binding glycoprotein that plays an important role in innate immunity against infections. We have previously demonstrated that selected peptides from bovine …
Author Archives: Taylor Mercado
Lactoferrin is a potential useful adjunct treatment for patients with chronic hepatitis C.
PMID: J Gastroenterol Hepatol. 2007 Nov ;22(11):1894-7. PMID: 17914966 Abstract Title: Effect of lactoferrin in patients with chronic hepatitis C: combination therapy with interferon and ribavirin. Abstract: OBJECTIVES: Lactoferrin has been reported to inhibit hepatitis C virus (HCV) infection in cultured human hepatocytes and HCV viremia in patients with chronic hepatitis C (CHC). The aim …
Lactoferrin inhibits hepatitis B virus infection in cultured human hepatocytes.
PMID: Hepatol Res. 2002 Nov ;24(3):228. PMID: 12393024 Abstract Title: Lactoferrin inhibits hepatitis B virus infection in cultured human hepatocytes. Abstract: We recently reported that lactoferrin (LF), a milk protein belonging to the iron transporter family, inhibits hepatitis C virus (HCV) infection in cultured human hepatocytes (PH5CH8) and that the interaction of LF with HCV …
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The present results provide evidence that lactoferrin may be useful as a preventive and/or therapeutic anti-norovirus agent.
PMID: Biochem Biophys Res Commun. 2013 May 17 ;434(4):791-6. Epub 2013 Apr 17. PMID: 23603257 Abstract Title: The protective effects of lactoferrin against murine norovirus infection through inhibition of both viral attachment and replication. Abstract: The purpose of this study was to evaluate the effects of bovine lactoferrin against norovirus infection using mouse norovirus (MNV) …
Bovine lactoferrin prevents the entry and intercellular spread of herpes simplex virus type 1 in Green Monkey Kidney cells.
PMID: Antiviral Res. 2007 Dec ;76(3):252-62. Epub 2007 Aug 30. PMID: 17881064 Abstract Title: Bovine lactoferrin prevents the entry and intercellular spread of herpes simplex virus type 1 in Green Monkey Kidney cells. Abstract: Lactoferrin (Lf) is a multifunctional glycoprotein that plays an important role in immune regulation and defence mechanisms against bacteria, fungi and …
Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells.
PMID: Antiviral Res. 1996 Mar ;29(2-3):221-31. PMID: 8739601 Abstract Title: Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells. Abstract: This paper describes the ability of human and bovine lactoferrins (HLf; BLf), iron-binding proteins belonging to the non-immune defense system, to interfere with herpes simplex virus type 1 (HSV-1) infection. Since lactoferrins are …
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Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV.
PMID: J Enzyme Inhib Med Chem. 2016 ;31(1):23-30. Epub 2015 Feb 16. PMID: 25683083 Abstract Title: Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV. Abstract: Two viral proteases of severe acute respiratory syndrome coronavirus (SARS-CoV), a chymotrypsin-like protease (3CL(pro)) and a papain-like protease (PL(pro)) are attractive targets for the development of anti-SARS drugs. …
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Riboflavin and UV light effectively reduced the titer of MERS-CoV in human plasma products to below the limit of detection.
PMID: Transfusion. 2016 12 ;56(12):2948-2952. Epub 2016 Nov 2. PMID: 27805261 Abstract Title: Inactivation of Middle East respiratory syndrome coronavirus (MERS-CoV) in plasma products using a riboflavin-based and ultraviolet light-based photochemical treatment. Abstract: BACKGROUND: Middle East respiratory syndrome coronavirus (MERS-CoV) has been identified as a potential threat to the safety of blood products. The Mirasol …
Emodin inhibits current through SARS-associated coronavirus 3a protein.
PMID: Antiviral Res. 2011 Apr ;90(1):64-9. Epub 2011 Feb 26. PMID: 21356245 Abstract Title: Emodin inhibits current through SARS-associated coronavirus 3a protein. Abstract: The open-reading-frame 3a of SARS coronavirus (SARS-CoV) had been demonstrated previously to form a cation-selective channel that may become expressed in the infected cell and is then involved in virus release. Drugs …
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Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells.
PMID: J Virol. 2004 Oct ;78(20):11334-9. PMID: 15452254 Abstract Title: Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells. Abstract: Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS, which caused a global panic in 2003. We describe here the screening of Chinese herbal medicine-based, novel small molecules …
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