PMID: PLoS One. 2011 ;6(8):e23710. Epub 2011 Aug 22. PMID: 21887302 Abstract Title: Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans. Abstract: It has been reported that lactoferrin (LF) participates in the host immune response against Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) invasion by enhancing NK cell activity and stimulating …
Author Archives: Taylor Mercado
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission.
PMID: J Virol. 2005 Mar ;79(5):3009-15. PMID: 15709021 Abstract Title: Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN–gp120 interaction. Abstract: One of the cell types first encountered by human immunodeficiency virus type 1 (HIV-1) following sexual transmission are dendritic cells (DC). DC capture HIV-1 through C-type lectin receptors, of …
Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo.
PMID: Antiviral Res. 2004 Sep ;63(3):197-208. PMID: 15451188 Abstract Title: Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo. Abstract: Lactoferrin is an antimicrobial agent, that, amongst other viruses, inhibits cytomegalovirus (CMV). In this study, we addressed the mechanism(s) by which lactoferrin interacts with CMV and its target cells to inhibit infection. We …
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Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein
PMID: Virology. 2008 Sep 15 ;379(1):143-51. Epub 2008 Jul 21. PMID: 18640695 Abstract Title: Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein. Abstract: Lactoferrin is a natural anti-microbial protein which affects Japanese encephalitis virus (JEV) activity. Binding of lactoferrin to cell surface expressed heparan sulfate (HS), …
Bovine lactoferrin inhibits influenza A virus induced programmed cell death in vitro.
PMID: Biometals. 2010 Jun ;23(3):465-75. Epub 2010 Mar 16. PMID: 20232110 Abstract Title: Bovine lactoferrin inhibits influenza A virus induced programmed cell death in vitro. Abstract: Influenza is one of the main plagues worldwide. The statistical likelihood of a new pandemic outbreak, together with the alarming emergence of influenza virus strains that are resistant to …
Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to glycosaminoglycans.
PMID: Virology. 2004 Jan 5 ;318(1):405-13. PMID: 14972565 Abstract Title: Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to glycosaminoglycans. Abstract: Previous reports have indicated that lactoferrin inhibits herpes simplex virus (HSV) infection during the very early phases of the viral replicative cycle. In the present work …
A review of the anti herpes simplex virus activity of lactoferrin and lactoferricin.
PMID: Cell Mol Life Sci. 2005 Dec ;62(24):3002-13. PMID: 16261265 Abstract Title: Anti herpes simplex virus activity of lactoferrin/lactoferricin — an example of antiviral activity of antimicrobial protein/peptide. Abstract: One of the most common viral infections in humans is caused by the herpes simplex virus (HSV). It was first effectively treated in the 1970s with …
Potential lactoferrin activity against pathogenic viruses.
PMID: C R Biol. 2014 Oct ;337(10):581-95. Epub 2014 Sep 22. PMID: 25282173 Abstract Title: Potential lactoferrin activity against pathogenic viruses. Abstract: Lactoferrin (LF) is an 80-kDa globular glycoprotein with high affinity for metal ions, particularly for iron. This protein possesses many biological functions, including the binding and release of iron and serves as one …
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Bovine lactoferrin activity against Chikungunya and Zika viruses
PMID: J Gen Virol. 2017 Jul ;98(7):1749-1754. Epub 2017 Jul 12. PMID: 28699858 Abstract Title: Bovine lactoferrin activity against Chikungunya and Zika viruses. Abstract: Chikungunya (CHIKV) and Zika (ZIKV) viruses are arboviruses which have recently broken their sylvatic isolation and gone on to spread rampantly among humans in some urban areas of the world, especially …
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Bovine lactoferrin inhibits dengue virus infectivity.
PMID: Int J Mol Sci. 2017 Sep 12 ;18(9). Epub 2017 Sep 12. PMID: 28895925 Abstract Title: Bovine Lactoferrin Inhibits Dengue Virus Infectivity by Interacting with Heparan Sulfate, Low-Density Lipoprotein Receptor, and DC-SIGN. Abstract: Bovine lactoferrin (bLF) presents in milk and has been shown to inhibit several viral infections. Effective drugs are unavailable for the …
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