Taylor Mercado

Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps.

n/a PMID: Cancer Prev Res (Phila). 2009 Nov ;2(11):975-83. Epub 2009 Oct 27. PMID: 19861543 Abstract Title: Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial. Abstract: Lactoferrin (LF), a secreted, iron binding glycoprotein originally discovered as a component of milk, is found in a …

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Antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis.

PMID: Biochim Biophys Acta. 2006 Oct ;1760(10):1536-44. Epub 2006 Jul 7. PMID: 16905260 Abstract Title: Antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis. Abstract: Combination chemoprevention using tea polyphenols as one of the components has received growing consideration in recent years. The present study was designed …

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Possible chemopreventive effects of bovine lactoferrin on esophagus and lung carcinogenesis.

PMID: Jpn J Cancer Res. 1999 Mar ;90(3):262-7. PMID: 10359039 Abstract Title: Possible chemopreventive effects of bovine lactoferrin on esophagus and lung carcinogenesis in the rat. Abstract: A milk component, bovine lactoferrin (bLF), previously shown by us to be a strong chemopreventive of colon carcinoma development, was examined for its influence on other organs using …

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Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.

PMID: J Cell Biochem. 1999 Sep 1 ;74(3):486-98. PMID: 10412049 Abstract Title: Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells. Abstract: Lactoferrin inhibits cell proliferation and suppresses tumor growth in vivo. However, the molecular mechanisms underlying these effects remain unknown. In this in vitro study, we demonstrate that treatment of …

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Liposomalization of lactoferrin enhanced its anti-tumoral effects on melanoma cells.

PMID: Biometals. 2010 Jun ;23(3):485-92. Epub 2010 Feb 27. PMID: 20191307 Abstract Title: Liposomalization of lactoferrin enhanced its anti-tumoral effects on melanoma cells. Abstract: A number of studies have reported the anti-tumoral activity of lactoferrin, a property mediated by a variety of mechanisms such as inhibitory effects on tumor cell growth, NK cell activation, and …

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The effect of LfcinB9 on human ovarian cancer cell SK-OV-3 is mediated by inducing apoptosis.

PMID: J Pept Sci. 2014 Oct ;20(10):803-10. Epub 2014 Jun 26. PMID: 24965354 Abstract Title: The effect of LfcinB9 on human ovarian cancer cell SK-OV-3 is mediated by inducing apoptosis. Abstract: LfcinB9 is a peptide derived from lactoferricin B. In the present study, the effect and relative mechanism of LfcinB9 on human ovarian cancer cell …

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The antiproliferative effect of bovine lactoferrin on canine mammary gland tumor cells.

PMID: J Vet Med Sci. 2008 May ;70(5):443-8. PMID: 18525164 Abstract Title: The antiproliferative effect of bovine lactoferrin on canine mammary gland tumor cells. Abstract: Lactoferrin has several biological activities, including antitumor activities in some human and animal tumor cells. Clinical trials have been carried out in human medicine based on these effects. However, the …

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Antitumor effect of human lactoferrin against newly established human pancreatic cancer cell line SPA.

PMID: Gan To Kagaku Ryoho. 1998 Aug ;25(10):1557-63. PMID: 9725049 Abstract Title: [Antitumor effect of human lactoferrin against newly established human pancreatic cancer cell line SPA]. Abstract: This paper describes the antitumor effect of human lactoferrin against the human pancreatic cancer cell line SPA, which was newly established in our laboratory from a metastatic liver …

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Inhibition of Epstein-Barr virus infection by lactoferrin.

PMID: J Innate Immun. 2012 ;4(4):387-98. Epub 2012 Mar 16. PMID: 22433582 Abstract Title: Inhibition of Epstein-Barr virus infection by lactoferrin. Abstract: Lactoferrin (LF) is a multifunctional glycoprotein that plays an important role in native immune defense against infections, including human herpetic viruses, such as cytomegalovirus and herpes simplex virus types 1 and 2. However, …

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Binding of lactoferrin to IGBP1 triggers apoptosis in a lung adenocarcinoma cell line.

PMID: Anticancer Res. 2011 Feb ;31(2):529-34. PMID: 21378334 Abstract Title: Binding of lactoferrin to IGBP1 triggers apoptosis in a lung adenocarcinoma cell line. Abstract: BACKGROUND: Lactoferrin (Lf), an iron-binding protein present in mammalian secretions, plays important roles in cancer prevention by inducing apoptosis.MATERIALS AND METHODS: PC-14 lung adenocarcinoma cells were exposed to bovine Lf (bLf) …

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