Depsidic gallotannins and simpler galloylated glucose derivatives all inhibit amyloid β-peptide (Aβ) aggregation in vitro, and monogalloylated α-glucogallin and a natural β-hexagalloylglucose are shown to be the strongest inhibitors.

PMID:  Angew Chem Int Ed Engl. 2015 Jul 6 ;54(28):8217-21. Epub 2015 May 26. PMID: 26013280 Abstract Title:  Gallotannins and Tannic Acid: First Chemical Syntheses and In Vitro Inhibitory Activity on Alzheimer's Amyloidβ-Peptide Aggregation. Abstract:  The screening of natural products in the search for new lead compounds against Alzheimer's disease has unveiled several plant polyphenols …

Beta-glucogallin may be a potential drug for the prevention of cataract development and progression.

PMID:  Med Sci Monit. 2019 Dec 7 ;25:9310-9318. Epub 2019 Dec 7. PMID: 31811113 Abstract Title:  Protective Effect ofβ-Glucogallin on Damaged Cataract Against Methylglyoxal Induced Oxidative Stress in Cultured Lens Epithelial Cells. Abstract:  BACKGROUNDß-glucogallin (GG) is one of the major plant polyphenolic antioxidants that have been associated with positive effects on human health and are …

Combination of epigallocatechin gallate and sulforaphane dounteracts In Vitro oxidative stress and delays stemness loss of amniotic fluid stem cells.

PMID:  Oxid Med Cell Longev. 2018 ;2018:5263985. Epub 2018 Dec 17. PMID: 30647811 Abstract Title:  Combination of Epigallocatechin Gallate and Sulforaphane Counteracts In Vitro Oxidative Stress and Delays Stemness Loss of Amniotic Fluid Stem Cells. Abstract:  Amniotic fluid stem cells (AFSCs) are characterizedby a unique niche guarantying their homeostatic role in the body. Maintaining the …

Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females.

PMID:  Appl Physiol Nutr Metab. 2018 Apr ;43(4):324-330. Epub 2017 Nov 6. PMID: 29106812 Abstract Title:  Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. Abstract:  A number of different forms of protein and their analogues have been investigated for their efficacy in ameliorating exercise-induced muscle damage (EIMD) and recovery. Preliminary data …

The effect of whey protein supplementation on the temporal recovery of muscle function following resistance training.

PMID:  Nutrients. 2018 Feb 16 ;10(2). Epub 2018 Feb 16. PMID: 29462923 Abstract Title:  The Effect of Whey Protein Supplementation on the Temporal Recovery of Muscle Function Following Resistance Training: A Systematic Review and Meta-Analysis. Abstract:  Whey protein (WP) is a widely consumed nutritional supplement, known to enhance strength and muscle mass during resistance training …

Whey protein supplementation can increase glutathione levels and improve nutritional status and immunity in cancer patients undergoing chemotherapy.

PMID:  J Med Food. 2018 Jun ;21(6):612-616. Epub 2018 Mar 12. PMID: 29565716 Abstract Title:  Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial. Abstract:  Clinical side effects from medical therapy play an important role in causing malnutrition among cancer patients. Whey protein isolates (WPIs) …

Role of glutathione in cancer progression and chemoresistance.

PMID:  Oxid Med Cell Longev. 2013 ;2013:972913. Epub 2013 May 20. PMID: 23766865 Abstract Title:  Role of glutathione in cancer progression and chemoresistance. Abstract:  Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and disturbances in GSH homeostasis are involved in the etiology and progression of …

Ascorbate could serve as a component of a topical antifungal therapy.

PMID:  Future Microbiol. 2016 12 ;11:1535-1547. Epub 2016 Nov 18. PMID: 27855492 Abstract Title:  Sodium ascorbate kills Candida albicans in vitro via iron-catalyzed Fenton reaction: importance of oxygenation and metabolism. Abstract:  AIM: Ascorbate can inhibit growth and even decrease viability of various microbial species including Candida albicans. However the optimum conditions and the mechanism of …

High doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo.

PMID:  Life Sci. 2019 Sep 1 ;232:116657. Epub 2019 Jul 13. PMID: 31306660 Abstract Title:  High doses of sodium ascorbate interfere with the expansion of glioblastoma multiforme cells in vitro and in vivo. Abstract:  AIMS: Constant development of chemotherapeutic strategies has considerably improved the efficiency of tumor treatment. However, adverse effects of chemotherapeutics enforce premature …

Sodium ascorbate as a quorum sensing inhibitor of Pseudomonas aeruginosa.

PMID:  J Appl Microbiol. 2014 Nov ;117(5):1388-99. Epub 2014 Oct 3. PMID: 25175797 Abstract Title:  Sodium ascorbate as a quorum sensing inhibitor of Pseudomonas aeruginosa. Abstract:  AIMS: Quorum sensing circuits regulate virulence factors in Pseudomonas aeruginosa and coordinate bacterial pathogenicity. We are interested in exploring available medications for their antiquorum sensing activity.METHODS AND RESULTS: First, …

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