PMID: Biomed Pharmacother. 2018 Jul ;103:362-372. Epub 2018 Apr 24. PMID: 29669302 Abstract Title: Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro. Abstract: Hepatocellular carcinoma (HCC) is characterized by elevation in the activity of sulfatase-2, an extracellular enzyme that catalyzes removal of 6-O-sulfate …
Author Archives: Taylor Mercado
Resveratrol might be useful for maintaining substantial L-ascorbic acid accumulation in the skin keratinocytes.
PMID: Mol Cell Biochem. 2020 Feb 21. Epub 2020 Feb 21. PMID: 32080778 Abstract Title: Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells. Abstract: L-Ascorbic acid (AsA), a reduced vitamin C (VC), is an important antioxidant, and the internal accumulation and maintenance of AsA are thought …
Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells.
PMID: J Cell Physiol. 2005 Jul ;204(1):192-7. PMID: 15672419 Abstract Title: Sodium ascorbate (vitamin C) induces apoptosis in melanoma cells via the down-regulation of transferrin receptor dependent iron uptake. Abstract: Sodium ascorbate (vitamin C) has a reputation for inconsistent effects upon malignant tumor cells, which vary from growth stimulation to apoptosis induction. Melanoma cells were …
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Safety Concerns With CBD
With the boom in CBD I am sure you have asked yourself, is this safe to put in your body? Not only is CBD becoming more popular in medicine, it is also showing up on menu items in bars and restaurants. It is even sold in pet products. In the US, CBD is legal in …
Panax notoginseng flower demonstrated a potential herb to treat rats with myocardial infarction.
PMID: Cardiol Res Pract. 2019 ;2019:8723076. Epub 2019 May 2. PMID: 31192006 Abstract Title: Primary Mechanism Study ofFlower (Herb) on Myocardial Infarction in Rats. Abstract: Background: (Burk.) F. H. Chen is one of the most common herbs in China. Because of its good efficacy and little adverse reaction,has been used widely to treat cardiovascular diseases …
Astragalus membranaceus treatment protects Raw264.7 cells from influenza virus.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:2971604. Epub 2019 Dec 31. PMID: 31975996 Abstract Title: Astragalus Membranaceus Treatment Protects Raw264.7 Cells from Influenza Virus by Regulating G1 Phase and the TLR3-Mediated Signaling Pathway. Abstract: Influenza is an acute respiratory infection disease caused by the influenza virus. At present, due to the high mutation rate …
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Panax notoginseng saponins promotes cutaneous wound healing and suppresses scar formation in mice.
PMID: J Cosmet Dermatol. 2020 Feb ;19(2):529-534. Epub 2019 Jul 2. PMID: 31267657 Abstract Title: Panax notoginseng saponins promotes cutaneous wound healing and suppresses scar formation in mice. Abstract: BACKGROUND & AIM: Panax notoginseng saponins are believed to promote wound healing due to its anti-proliferative effect on fibroblasts. The present work was therefore aimed to …
Fucoidan inhibition of osteosarcoma cells is species and molecular weight dependent.
PMID: Mar Drugs. 2020 Feb 8 ;18(2). Epub 2020 Feb 8. PMID: 32046368 Abstract Title: Fucoidan Inhibition of Osteosarcoma Cells Is Species and Molecular Weight Dependent. Abstract: Fucoidan is a brown algae-derived polysaccharide having several biomedical applications. This study simultaneously compares the anti-cancer activities of crude fucoidans fromand, and effects of low (LMW, 10-50 kDa), …
This study shows that fucoidan might become an effective therapeutic agent for patients already developed type I allergic diseases.
PMID: Biomolecules. 2020 Feb 9 ;10(2). Epub 2020 Feb 9. PMID: 32050429 Abstract Title: Oral Administration of Fucoidan Can Exert Anti-Allergic Activity after Allergen Sensitization by Enhancement of Galectin-9 Secretion in Blood. Abstract: A previous study revealed that fucoidan inhibited mast cell degranulation through the upregulation of galectin-9 in blood. The purpose of this study …
Low molecular weight fucoidan alleviates diabetic nephropathy.
PMID: Int J Biol Macromol. 2020 Feb 11 ;150:304-314. Epub 2020 Feb 11. PMID: 32057847 Abstract Title: Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells. Abstract: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease (ESRD). Currently, approximately 20-40% of individuals …
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