PMID: Pak J Biol Sci. 2019 Jan ;22(12):614-622. PMID: 31930861 Abstract Title: Antiviral Activity of Curcumin Loaded Milk Proteins Nanoparticles on Potato Virus Y. Abstract: BACKGROUND AND OBJECTIVE: Potato is one of the world's leading vegetable crops. Potato viral diseases cause adversely effects on the agricultural sector. Recently there is a growing interest to control …
Author Archives: Taylor Mercado
These findings indicate that natural shelled pistachio kernels have remarkable inhibitory activity against HSV-1.
PMID: Plants (Basel). 2020 Feb 18 ;9(2). Epub 2020 Feb 18. PMID: 32085514 Abstract Title: In Vitro Anti-HSV-1 Activity of Polyphenol-Rich Extracts and Pure Polyphenol Compounds Derived from Pistachios Kernels (L.). Abstract: Natural compounds are a prominent source of novel antiviral drugs. Several reports have previously shown the antimicrobial activity of pistachio polyphenol extracts. Therefore, …
This study has identified that calycosin and formononetin can increase the treatment effect of temozolomide.
PMID: J Ethnopharmacol. 2019 Oct 5 ;242:111699. Epub 2019 Apr 18. PMID: 31005632 Abstract Title: In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Astragalina alpestris is a traditional Chinese herbal medicine with anti-inflammatory, anti-immune, anti-tumor and other pharmacological effects. Calycosin and formononetin (FMN) …
The anti-inflammatory effects of formononetin and ononin on lipopolysaccharide-induced zebrafish models based on lipidomics and targeted transcriptomics.
PMID: Metabolomics. 2019 11 25 ;15(12):153. Epub 2019 Nov 25. PMID: 31768751 Abstract Title: The anti-inflammatory effects of formononetin and ononin on lipopolysaccharide-induced zebrafish models based on lipidomics and targeted transcriptomics. Abstract: INTRODUCTION: Formononetin (MBHS) and its glycosylated derivative ononin (MBHG), as the major isoflavones, have exhibited the anti-inflammatory impacts on the lipopolysaccharide (LPS)-induced inflammation. …
The oral administration of formononetin decelerated tumor growth through.
PMID: Oncol Rep. 2020 Feb ;43(2):700-710. Epub 2019 Dec 13. PMID: 31894318 Abstract Title: Formononetin induces apoptotic cell death through the suppression of mitogen‑activated protein kinase and nuclear factor‑κB phosphorylation in FaDu human head and neck squamous cell carcinoma cells. Abstract: Formononetin, a phytoestrogen extracted from various herbal plants, has been investigated as an anticancer …
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Inhibitory effects of formononetin on the monocrotaline‑induced pulmonary arterial hypertension.
PMID: Mol Med Rep. 2020 Mar ;21(3):1192-1200. Epub 2020 Jan 3. PMID: 31922224 Abstract Title: Inhibitory effects of formononetin on the monocrotaline‑induced pulmonary arterial hypertension in rats. Abstract: Pulmonary arterial hypertension (PAH) is a fatal syndrome resulting from enhanced pulmonary arterial pressure and pulmonary vessel resistance. Perivascular inflammation and extracellular matrix deposition are considered to …
Formononetin recovered injured nerve functions after ischemic stroke.
PMID: Biochem Biophys Res Commun. 2020 Feb 17. Epub 2020 Feb 17. PMID: 32081422 Abstract Title: Formononetin recovered injured nerve functions by enhancing synaptic plasticity in ischemic stroke rats. Abstract: BACKGROUND AND OBJECTIVES: Formononetin has protective effect against ischemic stroke. It's unclear whether it can restore the nerve functions after stroke.METHODS: SD rats were subjected …
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Formononetin attenuates Aβ25-35-induced cytotoxicity in HT22 cells.
PMID: Neurosci Lett. 2017 02 3 ;639:36-42. Epub 2016 Dec 26. PMID: 28034780 Abstract Title: Formononetin attenuates Aβ-induced cytotoxicity in HT22 cells via PI3K/Akt signaling and non-amyloidogenic cleavage of APP. Abstract: Amyloid beta (Aβ) is the main component of the amyloid plaques that accumulate in the brains of Alzheimer patients. Here, we reported the protective …
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Pharmacological network analysis was used to identify the gene targets and mechanisms of formononetin treatment in patients with Alzheimer’s disease.
PMID: Med Sci Monit. 2019 Jun 8 ;25:4273-4277. Epub 2019 Jun 8. PMID: 31175839 Abstract Title: Pharmacological Targets and the Biological Mechanisms of Formononetin for Alzheimer's Disease: A Network Analysis. Abstract: BACKGROUND This study aimed to identify the pharmacological targets and mechanisms of action of the traditional Chinese medicine, formononetin, in the treatment of Alzheimer's …
Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE-/- mice.
PMID: Theranostics. 2020 ;10(3):1090-1106. Epub 2020 Jan 1. PMID: 31938053 Abstract Title: Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoEmice. Abstract: : Atherosclerosis is an underlying cause of coronary heart disease. Foam cell, a hallmark of atherosclerosis, is prominently derived from monocyte-differentiated macrophage, and vascular smooth muscle cells (VSMCs) through unlimitedly …
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