Author Archives: Taylor Mercado

PMID:  Food Chem Toxicol. 2010 Jun ;48(6):1741-5. Epub 2010 Apr 9. PMID: 20385192 Abstract Title:  Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells. Abstract:  In the present study, the effect of astaxanthin on improvement of the proliferative capacity as well as the osteogenic and adipogenic …

Continue reading “Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells.”

PMID:  Avicenna J Med Biotechnol. 2018 Apr-Jun;10(2):69-74. PMID: 29849982 Abstract Title:  The Evaluation of Astaxanthin Effects on Differentiation of Human Adipose Derived Stem Cells into Oligodendrocyte Precursor Cells. Abstract:  Background: Multiple Sclerosis (MS) has been explained as an autoimmune mediated disorder in central nerve system. Since conventional therapies for MS are not able to stop …

Continue reading “Astaxanthin promotes the differentiation of human adipose-derived mesenchymal stem cells into oligodendrocyte precursor cells.”

PMID:  PLoS One. 2019 ;14(5):e0216755. Epub 2019 May 20. PMID: 31107886 Abstract Title:  Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles. Abstract:  Astaxanthin is a highly potent antioxidant which can be extracted from Haematococcus pluvialis when cultivated and induced at high stress conditions. Due to astaxanthin's hydrophobicity, methoxypolyethylene glycol-polycaprolactone (mPEG-PCL) copolymer …

Continue reading “Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles.”

PMID:  Materials (Basel). 2019 Jul 29 ;12(15). Epub 2019 Jul 29. PMID: 31362414 Abstract Title:  The Influence of Astaxanthin on the Proliferation of Adipose-derived Mesenchymal Stem Cells in Gelatin-Methacryloyl (GelMA) Hydrogels. Abstract:  Recently, astaxanthin, a red lipophilic pigment belonging to the xanthophyllic family of carotenoids, has shown the feasibility of its uses in tissue engineering …

Continue reading “Astaxanthin enhances adipose-derived mesenchymal stem cell proliferation in vitro.”

PMID:  Int J Mol Med. 2019 Dec ;44(6):2234-2244. Epub 2019 Sep 27. PMID: 31573052 Abstract Title:  Biological effects of melatonin on human adipose‑derived mesenchymal stem cells. Abstract:  Mesenchymal stem cells (MSCs) are capable of differentiating into other cell types and exhibit immunomodulatory effects. MSCs are affected by several intrinsic and extrinsic signaling modulators, including growth …

Continue reading “This study confirms the role of melatonin in enhancing the biological activities of adipose-derived stem cells.”

PMID:  Stem Cell Res Ther. 2019 10 17 ;10(1):306. Epub 2019 Oct 17. PMID: 31623678 Abstract Title:  Antioxidants inhibit cell senescence and preserve stemness of adipose tissue-derived stem cells by reducing ROS generation during long-term in vitro expansion. Abstract:  BACKGROUND: Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising candidates for regenerative medicine. However, long-term in …

Continue reading “Antioxidants inhibit cell senescence and preserve stemness of adipose tissue-derived stem cells by reducing ROS generation during long-term in vitro expansion.”

PMID:  Stem Cell Res Ther. 2019 Dec 21 ;10(1):408. Epub 2019 Dec 21. PMID: 31864412 Abstract Title:  Melatonin promotes the BMP9-induced osteogenic differentiation of mesenchymal stem cells by activating the AMPK/β-catenin signalling pathway. Abstract:  BACKGROUND: Mesenchymal stem cells (MSCs) play a crucial role in maintaining the dynamic balance of bone metabolism. Melatonin may have a …

Continue reading “Melatonin promotes the BMP9-induced osteogenic differentiation of mesenchymal stem cells by activating the AMPK/β-catenin signalling pathway.”

PMID:  Stem Cells Int. 2019 ;2019:6568394. Epub 2019 Dec 30. PMID: 32082385 Abstract Title:  Melatonin Reverses the Loss of Stemness Induced by TNF-in Human Bone Marrow Mesenchymal Stem Cells through Upregulation of YAP Expression. Abstract:  Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and disease treatment. However, long-termculture results in loss of MSC …

Continue reading “These results suggest that melatonin can reverse the loss of stemness caused by inflammatory factor TNF-α in bone marrow mesenchymal stem cells.”

PMID:  Toxicol Appl Pharmacol. 2020 Jan 15 ;387:114851. Epub 2019 Dec 5. PMID: 31812774 Abstract Title:  Thymoquinone promotes mouse mesenchymal stem cells migration in vitro and induces their immunogenicity in vivo. Abstract:  Mesenchymal stem cells (MSCs) have unique potentials, including migration and immunomodulation. Identification of the factors that enhance these activities can improve clinical applications …

Continue reading “Thymoquinone promotes mouse mesenchymal stem cells migration in vitro and induces their immunogenicity in vivo.”

PMID:  World J Stem Cells. 2019 Dec 26 ;11(12):1045-1064. PMID: 31875868 Abstract Title:  Influence of olive oil and its components on mesenchymal stem cell biology. Abstract:  Extra virgin olive oil is characterized by its high content of unsaturated fatty acid residues in triglycerides, mainly oleic acid, and the presence of bioactive and antioxidant compounds. Its …

Continue reading “Olive oil confers benefit to mesenchymal stem cell populations.”