Author Archives: Taylor Mercado

PMID:  Zhejiang Da Xue Xue Bao Yi Xue Ban. 2019 Dec 25 ;48(6):617-624. PMID: 31955535 Abstract Title:  [Effects of resveratrol on aging of mesenchymal stem cells and its mechanism]. Abstract:  OBJECTIVE: To investigate the effects of resveratrol (Res) on aging of marrow mesenchymal stem cells (MSCs), and to explore its mechanism.METHODS: MSCs were isolated from …

Continue reading “Resveratrol can protect the mitochondrial function of mesenchymal stem cells and effectively delay the mesenchymal stem cells senescence.”

PMID:  Adv Pharm Bull. 2020 Jan ;10(1):88-96. Epub 2019 Dec 11. PMID: 32002366 Abstract Title:  Resveratrol Effect on Adipose-Derived Stem Cells Differentiation to Chondrocyte in Three-Dimensional Culture. Abstract:  Adipose stem cells (ASCs) are pluripotent cells with the ability of self-renewal and differentiation into different types of mesenchymal cells. As cartilage repair is difficult due to …

Continue reading “Resveratrol enhances adipose-derived stem cell differentiation to chondrocytes in vitro.”

PMID:  Chem Biol Interact. 2019 Feb 1 ;299:131-139. Epub 2018 Dec 11. PMID: 30543783 Abstract Title:  Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways. Abstract:  Liver fibrosis is a pathological wound-healing response caused by chronic liver damage due to a virus, autoimmune disorder, or drugs. Hepatic …

Continue reading “Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways.”

PMID:  Saudi J Biol Sci. 2019 Jan ;26(1):201-209. Epub 2017 Sep 21. PMID: 30622427 Abstract Title:  Influence of resveratrol on liver fibrosis induced by dimethylnitrosamine in male rats. Abstract:  Liver fibrosis is a significant health problem which represents the liver's scarring process and response to injury through deposition of collagen and extracellular matrix, and ultimately …

Continue reading “Resveratrol has a marked protective role on dimethylnitrosamine-induced liver fibrosis in rats, and can be considered as antiproliferative, antihypertensive, as well as antifibrotic agent and may be used to block the development of liver fibrosis.”

PMID:  Cell Tissue Res. 2018 Oct ;374(1):111-120. Epub 2018 Jun 27. PMID: 29951700 Abstract Title:  Cytoprotective role of vitamin E in porcine adipose-tissue-derived mesenchymal stem cells against hydrogen-peroxide-induced oxidative stress. Abstract:  Survival of mesenchymal stem cells (MSCs) against oxidative stress and inflammation is vital for effective stem cell therapy. The reactive oxygen species (ROS) result …

Continue reading “Vitamin E protects porcine adipose-tissue-derived mesenchymal stem cells against hydrogen-peroxide-induced oxidative stress.”

PMID:  Molecules. 2018 Dec 6 ;23(12). Epub 2018 Dec 6. PMID: 30563251 Abstract Title:  (-)-Epigallocatechin-3-Gallate (EGCG) Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells. Abstract:  Osteoporosis is the second most-prevalent epidemiologic disease in the aging population worldwide. Cross-sectional and retrospective evidence indicates that tea consumption can mitigate bone loss and reduce risk of …

Continue reading “Epigallocatechin-3-gallate (EGCG) enhances osteogenic differentiation of human bone marrow mesenchymal stem cells.”

PMID:  Biochem Biophys Rep. 2019 Dec ;20:100678. Epub 2019 Aug 16. PMID: 31467991 Abstract Title:  Antifibrotic effect of methylated quercetin derivatives on TGFβ-induced hepatic stellate cells. Abstract:  Quercetin (QCT) and isorhamnetin (ISO), natural flavonoids, were both shown to possess antifibrotic activity inandmodels of hepatic fibrosis. Although ISO is a direct metabolite of QCT differing by …

Continue reading “The antifibrotic effect of quercetin can be enhanced by adding methyl group on functionally important position.”

PMID:  Clin Respir J. 2018 Jul ;12(7):2220-2227. Epub 2018 Apr 16. PMID: 29570946 Abstract Title:  Serum 25-hydroxyvitamin D levels in hospitalized adults with community-acquired pneumonia. Abstract:  INTRODUCTION: Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to …

Continue reading “Hospitalized adults with community-acquired pneumoniahave lower 25OHD levels and would be associated with its severity.”

PMID:  Korean J Intern Med. 2018 11 ;33(6):1129-1136. Epub 2018 Jun 20. PMID: 29914229 Abstract Title:  Effect of vitamin D deficiency in Korean patients with acute respiratory distress syndrome. Abstract:  BACKGROUND/AIMS: Vitamin D modulates innate and adaptive immune responses, and vitamin D deficiency is associated with increased mortality in hospitalized patients with pneumonia. We evaluated …

Continue reading “Vitamin D deficiency was prevalent in Korean patients with acute respiratory distress syndrome.”

PMID:  Rep Biochem Mol Biol. 2019 Apr ;8(1):85-90. PMID: 31334293 Abstract Title:  Association of Vitamin D Status with the Severity and Mortality of Community-Acquired Pneumonia in Iran during 2016-2017: A Prospective Cohort Study. Abstract:  Background: Community-acquired pneumonia (CAP) is a common disease considered as a major public health problem. It causes considerable morbidity and mortality …

Continue reading “Pneumonia severity and mortality risk were greater and hospital stays longer in vitamin D-deficient patients.”