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Author Archives: Taylor Mercado
Antiproliferative and apoptotic effects of proteins from black seeds (Nigella sativa) on human breast MCF-7 cancer cell line.
PMID: BMC Complement Med Ther. 2020 Jan 13 ;20(1):5. Epub 2020 Jan 13. PMID: 32020890 Abstract Title: Antiproliferative and apoptotic effects of proteins from black seeds (Nigella sativa) on human breast MCF-7 cancer cell line. Abstract: BACKGROUND: Nigella sativa (NS), a member of family Ranunculaceae is commonly known as black seed or kalonji. It has …
The protective effect of Nigella sativa extract on lung inflammation and oxidative stress induced by lipopolysaccharide.
PMID: J Ethnopharmacol. 2020 Feb 6 ;253:112653. Epub 2020 Feb 6. PMID: 32035219 Abstract Title: The protective effect of Nigella sativa extract on lung inflammation and oxidative stress induced by lipopolysaccharide in rats. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Oxidative stress during inflammation can increase inflammation and damage tissue. Nigella sativa L. (NS) showed many pharmacological properties including …
Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis.
PMID: J Ethnopharmacol. 2020 Mar 1 ;249:112416. Epub 2019 Nov 19. PMID: 31756448 Abstract Title: Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis in pig model. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Mulberry leaves are the dry leaves of Morus nigra L. trees, which are widely cultivated in central and southern …
The effect of vitamin D on restless legs syndrome: prospective self-controlled case study.
PMID: Sleep Breath. 2020 Feb 20. Epub 2020 Feb 20. PMID: 32078093 Abstract Title: The effect of vitamin D on restless legs syndrome: prospective self-controlled case study. Abstract: PURPOSE: To evaluate the effect of vitamin D on severity of restless legs syndrome in patients with idiopathic restless legs syndrome (RLS).METHODS: Patients with idiopathic RLS completed …
Morus nigra leaves extract revokes the depressive-like behavior, oxidative stress, and hippocampal damage induced by corticosterone.
PMID: Behav Pharmacol. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32040015 Abstract Title: Morus nigra leaves extract revokes the depressive-like behavior, oxidative stress, and hippocampal damage induced by corticosterone: a pivotal role of the phenolic syringic acid. Abstract: The pathophysiology of depression includes glucocorticoids excess, glutamatergic excitotoxicity, and oxidative stress impairment. Previous study demonstrated …
Thymoquinone can be developed as a potential therapeutic modularity in bleomycin-induced lung fibrosis for human use.
PMID: Exp Lung Res. 2020 Feb 13:1-11. Epub 2020 Feb 13. PMID: 32053036 Abstract Title: Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis. Abstract: The present study investigates the therapeutic potential of thymoquinone (TQ) in bleomycin-induced lung fibrosis (BMILF) and elucidates the target-signaling pathway …
Astragaloside IV suppresses inflammatory response via suppression of NF-κB, and MAPK signalling in human bronchial epithelial cells.
PMID: Arch Physiol Biochem. 2020 Feb 14:1-10. Epub 2020 Feb 14. PMID: 32057253 Abstract Title: Astragaloside IV suppresses inflammatory response via suppression of NF-κB, and MAPK signalling in human bronchial epithelial cells. Abstract: Astragaloside IV isolated from(Fisch.), which was reported to have anti-tumor, anti-asthma, and suppressed cigarette smoke-induced lung inflammation in mice.This study investigated whether …
Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis.
PMID: Biomed Pharmacother. 2020 Apr ;124:109911. Epub 2020 Jan 28. PMID: 32004939 Abstract Title: Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis. Abstract: Total glucosides of paeony (TGP), an active mixture extracted from paeony root, has anti-inflammatory and immunoregulatory effects and is widely used for the …
Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells.
PMID: Pharmacol Rep. 2020 Feb 11. Epub 2020 Feb 11. PMID: 32048269 Abstract Title: Synergistic effects of tanshinone IIA and andrographolide on the apoptosis of cancer cells via crosstalk between p53 and reactive oxygen species pathways. Abstract: BACKGROUND: Tanshinone IIA (Tan IIA) and andrographolide (Andro) are natural compounds that are reported to exhibit anticancer activities …
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