PMID: Methods Mol Biol. 2020 ;2062:3-33. PMID: 31768969 Abstract Title: The RNA Exosome and Human Disease. Abstract: The evolutionarily conserved RNA exosome is a multisubunit ribonuclease complex that processes and/or degrades numerous RNAs. Recently, mutations in genes encoding both structural and catalytic subunits of the RNA exosome have been linked to human disease. Mutations in …
Author Archives: Taylor Mercado
L-ascorbic acid can be useful in breast cancer treatment.
PMID: Nutrients. 2020 May 8 ;12(5). Epub 2020 May 8. PMID: 32397306 Abstract Title: L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus. Abstract: Anticancer effects of L-ascorbic acid (Vitamin C, L-AA) have been reported in various types of cancers. L-AA intake reduces breast cancer recurrence and …
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Vitamin C versus cancer: Ascorbic acid radical and impairment of mitochondrial respiration?
PMID: Oxid Med Cell Longev. 2020 ;2020:1504048. Epub 2020 Jan 11. PMID: 32411317 Abstract Title: Vitamin C versus Cancer: Ascorbic Acid Radical and Impairment of Mitochondrial Respiration? Abstract: Vitamin C as a cancer therapy has a controversial history. Much of the controversy arises from the lack of predictive biomarkers for stratification of patients, as well …
Exogenous vitamin C triggered structural changes of redox-activated dual core-crosslinked biodegradable nanogels for boosting the antitumor efficiency.
PMID: J Mater Chem B. 2020 May 15. Epub 2020 May 15. PMID: 32412025 Abstract Title: Exogenous vitamin C triggered structural changes of redox-activated dual core-crosslinked biodegradable nanogels for boosting the antitumor efficiency. Abstract: Premature leakage of drugs during blood circulation and slow drug release at the tumor site are two major challenges that nanocarriers …
Therapeutic target and molecular mechanism of vitamin C-treated pneumonia: a systematic study of network pharmacology.
PMID: Food Funct. 2020 May 18. Epub 2020 May 18. PMID: 32420559 Abstract Title: Therapeutic target and molecular mechanism of vitamin C-treated pneumonia: a systematic study of network pharmacology. Abstract: Vitamin C (VC), a well-reported antioxidant, is found with beneficial actions of preventing and treating pneumonia. However, the detailed pharmacological target and mechanism of VC-treated …
Extracellular vesicles and ebola virus: A new mechanism of immune evasion.
PMID: Viruses. 2019 May 2 ;11(5). Epub 2019 May 2. PMID: 31052499 Abstract Title: Extracellular Vesicles and Ebola Virus: A New Mechanism of Immune Evasion. Abstract: Ebola virus (EBOV) disease can result in a range of symptoms anywhere from virtually asymptomatic to severe hemorrhagic fever during acute infection. Additionally, spans of asymptomatic persistence in recovering …
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Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2
PMID: Nat Commun. 2019 06 3 ;10(1):2402. Epub 2019 Jun 3. PMID: 31160588 Abstract Title: Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2. Abstract: Platelet-leukocyte interactions amplify inflammatory reactions, but the underlying mechanism is still unclear. CLEC5A and CLEC2 are spleen tyrosine kinase (Syk)-coupled C-type lectin receptors, abundantly expressed by leukocytes and …
Exosomes carry microRNAs into neighbouring cells to promote diffusive infection of Newcastle disease virus.
PMID: Viruses. 2019 Jun 6 ;11(6). Epub 2019 Jun 6. PMID: 31174402 Abstract Title: Exosomes Carry microRNAs into Neighboring Cells to Promote Diffusive Infection of Newcastle Disease Virus. Abstract: Newcastle disease virus (NDV), an avian paramyxovirus, was shown to prefer to replicate in tumor cells instead of normal cells; however, this mechanism has not been …
Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus.
PMID: Sci Rep. 2020 May 14 ;10(1):7939. Epub 2020 May 14. PMID: 32409751 Abstract Title: Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. Abstract: Enteroviruses support cell-to-cell viral transmission prior to their canonical lytic spread of virus. Poliovirus (PV), a prototype for human pathogenic positive-sense RNA enteroviruses, and picornaviruses in …
Should You Wear a Mask to Prevent COVID-19?
This article is copyrighted by GreenMedInfo LLC, 2020Visit our Re-post guidelines States are increasingly mandating the use of face masks in public places, but evidence suggests face coverings do little to reduce risk of illness and, in some cases, may even increase your likelihood of contamination. As recently as February 29, 2020, U.S. Surgeon General …
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