PMID: Environ Int. 2020 Feb 13 ;137:105560. Epub 2020 Feb 13. PMID: 32062438 Abstract Title: Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression. Abstract: Arsenic and benzo[a]pyrene (BaP) are among the most common environmental carcinogens causing lung cancer. Millions of people are exposed to …
Author Archives: Taylor Mercado
Betaine supplementation attenuates hepatic injury mediated by cisplatin.
PMID: Pharmacol Rep. 2019 Nov ;71(6):1025-1033. Epub 2019 Jun 6. PMID: 32002889 Abstract Title: Inhibition of NF-κB and the oxidative stress -dependent caspase-3 apoptotic pathway by betaine supplementation attenuates hepatic injury mediated by cisplatin in rats. Abstract: BACKGROUND: Cisplatin is a major anti-cancer drug commonly used in the treatment of various cancers; nevertheless, the associated …
Continue reading “Betaine supplementation attenuates hepatic injury mediated by cisplatin.”
Hyperuricemia as a potential plausible risk factor for periodontitis.
PMID: Med Hypotheses. 2020 Jan 23 ;137:109591. Epub 2020 Jan 23. PMID: 32007821 Abstract Title: Hyperuricemia as a potential plausible risk factor for periodontitis. Abstract: Elevated blood uric acid (UA) levels have been positively associated with the severity of periodontitis. It thus brings out a hypothesis that hyperuricemia, a pathological elevation of blood UA, might …
Continue reading “Hyperuricemia as a potential plausible risk factor for periodontitis.”
Microbial dysbiosis-induced obesity: Role of gut microbiota in homeostasis of energy metabolism.
PMID: Br J Nutr. 2020 Feb 3:1-23. Epub 2020 Feb 3. PMID: 32008579 Abstract Title: Microbial dysbiosis-induced obesity: Role of gut microbiota in homeostasis of energy metabolism. Abstract: The global obesity epidemic has necessitated the search for better intervention strategies including the exploitation of the health benefits of some gut microbiota and their metabolic products. …
Mechanism of action and the effect of beta-hydroxy-beta-methylbutyrate supplementation on different types of physical performance – A systematic review.
PMID: J Hum Kinet. 2019 Aug ;68:211-222. Epub 2019 Aug 21. PMID: 31531146 Abstract Title: Mechanism of Action and the Effect of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Different Types of Physical Performance – A Systematic Review. Abstract: Beta-hydroxy-beta-methylbutyrate (HMB) has been used extensively as a dietary supplement for athletes and physically active people. HMB is a …
Low dose cadmium can cause dysbiosis of the gut microbiota.
PMID: Microorganisms. 2020 Feb 5 ;8(2). Epub 2020 Feb 5. PMID: 32033263 Abstract Title: The Dysbiosis of Gut Microbiota Caused by Low-Dose Cadmium Aggravate the Injury of Mice Liver through Increasing Intestinal Permeability. Abstract: Cadmium (Cd), widely present in food and drinking water at low doses, can cause health risks. However, the mechanistic effects of …
Continue reading “Low dose cadmium can cause dysbiosis of the gut microbiota.”
Melatonin controls microbiota in colitis by goblet cell differentiation and antimicrobial peptide production.
PMID: Sci Rep. 2020 Feb 10 ;10(1):2232. Epub 2020 Feb 10. PMID: 32042047 Abstract Title: Melatonin controls microbiota in colitis by goblet cell differentiation and antimicrobial peptide production through Toll-like receptor 4 signalling. Abstract: Microbial dysbiosis has long been postulated to be associated with the pathogenesis of inflammatory bowel disease (IBD). Although evidence supporting the …
Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease.
PMID: NMR Biomed. 2020 Feb 17:e4258. Epub 2020 Feb 17. PMID: 32066202 Abstract Title: Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease. Abstract: Metabolic heart disease (MHD), which is strongly associated with heart failure with preserved ejection fraction, is characterized by reduced mitochondrial energy production and contractile performance. …
Butyrate ameliorates antibiotic-driven type 1 diabetes in the female offspring of non-obese diabetic mice.
PMID: J Agric Food Chem. 2020 Feb 12. Epub 2020 Feb 12. PMID: 32046486 Abstract Title: Butyrate Ameliorates Antibiotic-driven Type 1 Diabetes in the Female Offspring of Non-Obese Diabetic Mice. Abstract: Maternal gut dysbiosis affects the development of offspring immune system. Our previous study has indicated that microbial metabolite butyrate directly shapes pancreatic immune tolerance …
These findings suggest that dysbiosis gut microbiome contributes to development of depression.
PMID: Oxid Med Cell Longev. 2019 ;2019:7902874. Epub 2019 Oct 24. PMID: 31772709 Abstract Title: The Gut Microbiome Modulates the Changes in Liver Metabolism and in Inflammatory Processes in the Brain of Chronic Unpredictable Mild Stress Rats. Abstract: Generally, depression is the result of complex gene-environment interactions. Recent studies have showed that the gut microbiota …
Health Time 