Antidepressive mechanisms of probiotics and their therapeutic potential.

PMID:  Front Neurosci. 2019 ;13:1361. Epub 2020 Jan 14. PMID: 32009871 Abstract Title:  Antidepressive Mechanisms of Probiotics and Their Therapeutic Potential. Abstract:  The accumulating knowledge of the host-microbiota interplay gives rise to the microbiota-gut-brain (MGB) axis. The MGB axis depicts the interkingdom communication between the gut microbiota and the brain. This communication process involves the …

Hyperlipidemia-induced lipotoxicity and immune activation in rats are prevented by curcumin and rutin.

PMID:  Int Immunopharmacol. 2020 Jan 30 ;81:106217. Epub 2020 Jan 30. PMID: 32007794 Abstract Title:  Hyperlipidemia-induced lipotoxicity and immune activation in rats are prevented by curcumin and rutin. Abstract:  We assessed the effects of curcumin, rutin, and the association of rutin and curcumin in organs of hyperlipidemic rats. Rutin and curcumin have notable antioxidant and …

Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis

PMID:  Mol Biol Rep. 2020 Feb 6. Epub 2020 Feb 6. PMID: 32030599 Abstract Title:  Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions. Abstract:  The purpose of the current study was to examine the neuroprotective effect of rutin against colistin-induced neurotoxicity in rats. Thirty-five …

Gut dysbiosis is prevailing in Sjögren’s syndrome and is related to dry eye severity.

PMID:  PLoS One. 2020 ;15(2):e0229029. Epub 2020 Feb 14. PMID: 32059038 Abstract Title:  Gut dysbiosis is prevailing in Sjögren's syndrome and is related to dry eye severity. Abstract:  OBJECTIVE: To investigate gut dysbiosis in patients with Sjögren's syndrome (SS) or dry eye syndrome (DES) compared to normal subjects and to evaluate the association of dysbiosis …

Gut-brain communication in demyelinating disorders.

PMID:  Curr Opin Neurobiol. 2020 Feb 14 ;62:92-101. Epub 2020 Feb 14. PMID: 32066076 Abstract Title:  Gut-brain communication in demyelinating disorders. Abstract:  Multiple Sclerosis (MS) is an autoimmune demyelinating disorder resulting from the interplay of genetic predisposition and environmental variables, including gut microbiota, diet and life style factors. Here, we first discuss the evidence supporting …

Gut microbial dysbiosis is associated with profibrotic factors in liver fibrosis mice.

PMID:  Front Cell Infect Microbiol. 2020 ;10:18. Epub 2020 Jan 31. PMID: 32083022 Abstract Title:  Gut Microbial Dysbiosis Is Associated With Profibrotic Factors in Liver Fibrosis Mice. Abstract:  Continuous development will evolve into end-stage liver disease. Profibrotic factors NOX4 and RhoA participate in the activation of HSC and accelerate the development of liver fibrosis. Abnormal …

Role of rutin nanoemulsion in ameliorating oxidative stress.

PMID:  Chem Phys Lipids. 2020 Feb 4 ;228:104890. Epub 2020 Feb 4. PMID: 32032570 Abstract Title:  Role of Rutin Nanoemulsion in Ameliorating Oxidative Stress: Pharmacokinetic and Pharmacodynamics Studies. Abstract:  Parkinson's disease is caused due to free radical generation in dopamine neurons leading to oxidative stress induced damage. The aim of this work was to ameliorate …

Dysbiosis of the gut and lung microbiome has a role in asthma.

PMID:  Semin Immunopathol. 2020 Feb 18. Epub 2020 Feb 18. PMID: 32072252 Abstract Title:  Dysbiosis of the gut and lung microbiome has a role in asthma. Abstract:  Worldwide 300 million children and adults are affected by asthma. The development of asthma is influenced by environmental and other exogenous factors synergizing with genetic predisposition, and shaping …

Yogurt intake may be associated with decreased odds of hyperplastic polyp and adenomatous polyps.

PMID:  Br J Nutr. 2020 Feb 20:1-28. Epub 2020 Feb 20. PMID: 32077397 Abstract Title:  Yogurt consumption and colorectal polyps. Abstract:  Diet modifies the risk of colorectal cancer (CRC) and inconclusive evidence suggests yogurt may protect against CRC. We analyzed data collected from two separate colonoscopy-based case-control studies. The Tennessee Colorectal Polyp Study (TCPS) and …

Anticancer activity of rutin and its combination with ionic liquids on renal cells.

PMID:  Biomolecules. 2020 Feb 4 ;10(2). Epub 2020 Feb 4. PMID: 32033222 Abstract Title:  Anticancer Activity of Rutin and Its Combination with Ionic Liquids on Renal Cells. Abstract:  The renal cell carcinoma (RCC) is the most common type of kidney cancer. Identifying novel and more effective therapies, while minimizing toxicity, continues to be fundamental in …

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