Author Archives: Taylor Mercado

PMID:  Photomed Laser Surg. 2016 Nov ;34(11):556-563. Epub 2016 May 31. PMID: 27244220 Abstract Title:  Mesenchymal Stem Cells Synergize with 635, 532, and 405 nm Laser Wavelengths in Renal Fibrosis: A Pilot Study. Abstract:  OBJECTIVE: To address whether a single treatment of one of three visible light wavelengths, 635, 532, and 405 nm (constant wave, energy density …

Continue reading “Mesenchymal Stem Cells Synergize with 635, 532, and 405 nm Laser Wavelengths in Renal Fibrosis.”

PMID:  J Integr Med. 2016 May ;14(3):165-73. PMID: 27181123 Abstract Title:  Interventional mechanisms of herbs or herbal extracts on renal interstitial fibrosis. Abstract:  Renal interstitial fibrosis (RIF) is a common development in chronic renal diseases that can lead to uremia and be life-threatening. The RIF pathology has complicated extracellular and intercellular mechanisms, involving many cells …

Continue reading “Tetramethylpyrazine/ligustrazine, curcumin, and polyglucoside of Tripterygium have experimentally shown good potential for improving renal interstitial fibrosis.”

PMID:  Biofactors. 2017 Mar ;43(2):272-282. Epub 2016 Nov 1. PMID: 27801960 Abstract Title:  Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells. Abstract:  The sphingosine kinase 1/sphingosine 1-phosphate (SphK1/S1P) system is involved in different pathological processes, including fibrogenesis. Melatonin abrogates activation of hepatic stellate cells (HSCs) …

Continue reading “Abrogation of the lipid signaling pathway by the indole reveals novel molecular pathways that may account for the protective effect of melatonin in liver fibrogenesis.”

PMID:  J Int Med Res. 2019 Feb ;47(2):884-892. Epub 2019 Jan 11. PMID: 30632430 Abstract Title:  Reversal effect of Zhigancao decoction on myocardial fibrosis in a rapid pacing-induced atrial fibrillation model in New Zealand rabbits. Abstract:  OBJECTIVE: To evaluate the effect of Zhigancao decoction on reversal of right atrial myocardial fibrosis after rapid atrial pacing …

Continue reading “Zhigancao decoction can reverse atrial fibrillation-induced myocardial fibrosis in rabbits.”

PMID:  BMC Complement Altern Med. 2019 Oct 30 ;19(1):290. Epub 2019 Oct 30. PMID: 31666058 Abstract Title:  Effect of Nigella sativa and its bioactive compound on type 2 epithelial to mesenchymal transition: a systematic review. Abstract:  BACKGROUND: Nigella sativa or commonly known as black seed or black cumin is one of the most ubiquitous complementary …

Continue reading “Nigella sativa and thymoquinone have been shown to promote wound healing, attenuate tissue inflammation, and prevent organ fibrosis via regulation of the epithelial to mesenchymal transition process.”

PMID:  Lasers Med Sci. 2019 Feb ;34(1):1-10. Epub 2018 Oct 26. PMID: 30367294 Abstract Title:  Adipose-derived mesenchymal stem cells treatments for fibroblasts of fibrotic scar via downregulating TGF-β1 and Notch-1 expression enhanced by photobiomodulation therapy. Abstract:  [n/a] read more

PMID:  Mol Cell Biochem. 2015 Sep ;407(1-2):263-79. Epub 2015 Jun 16. PMID: 26077659 Abstract Title:  Troxerutin reverses fibrotic changes in the myocardium of high-fat high-fructose diet-fed mice. Abstract:  A previous study from our laboratory showed that troxerutin (TX) provides cardioprotection by mitigating lipid abnormalities in a high-fat high-fructose diet (HFFD)-fed mice model of metabolic syndrome …

Continue reading “Troxerutin reverses fibrotic changes in the myocardium of high-fat high-fructose diet-fed mice.”

PMID:  Biomed Res Int. 2015 ;2015:935903. Epub 2015 Dec 31. PMID: 26881209 Abstract Title:  Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells. Abstract:  Activation of hepatic stellate cells (HSCs) depending on epithelial-to-mesenchymal transition (EMT) reflects the key event of liver fibrosis. Contrastively, mesenchymal-to-epithelial transition …

Continue reading “Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells.”

PMID:  Int J Mol Sci. 2015 Nov 25 ;16(12):27988-8000. Epub 2015 Nov 25. PMID: 26602917 Abstract Title:  Application of Green Tea Catechin for Inducing the Osteogenic Differentiation of Human Dedifferentiated Fat Cells in Vitro. Abstract:  Despite advances in stem cell biology, there are few effective techniques to promote the osteogenic differentiation of human primary dedifferentiated …

Continue reading “Application of green tea catechin facilitates early osteogenic differentiation and mineralization of human primary dedifferentiated fat cells in vitro.”

PMID:  Epigenetics. 2018 ;13(2):156-162. Epub 2018 Mar 7. PMID: 28055298 Abstract Title:  Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D. Abstract:  Inflammation of adipose tissue is believed to be a contributing factor to many chronic diseases associated with obesity. …

Continue reading “Vitamin D Limits Inflammation-Linked microRNA Expression in Adipocytes in Vitro and in Vivo: A New Mechanism for the Regulation of Inflammation by Vitamin D”