n/a PMID: Pharmacol Res. 2020 Feb ;152:104579. Epub 2019 Nov 30. PMID: 31790820 Abstract Title: Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: A focus on human studies. Abstract: In the last decade, the prevalence of autism spectrum disorders (ASD) has dramatically escalated worldwide. Currently available drugs mainly target some …
Author Archives: Taylor Mercado
Ameliorating liver fibrosis in an animal model using the secretome released from miR-122-transfected adipose-derived stem cells.
PMID: World J Stem Cells. 2019 Nov 26 ;11(11):990-1004. PMID: 31768225 Abstract Title: Ameliorating liver fibrosis in an animal model using the secretome released from miR-122-transfected adipose-derived stem cells. Abstract: BACKGROUND: Recently, the exclusive use of mesenchymal stem cell (MSC)-secreted molecules, called secretome, rather than cells, has been evaluated for overcoming the limitations of cell-based …
Luteolin may represent a promising candidate for the treatment of intracerebral hemorrhage-induced secondary brain injury.
PMID: Front Pharmacol. 2019 ;10:1551. Epub 2020 Jan 21. PMID: 32038239 Abstract Title: Luteolin Exerts NeuroprotectionModulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage. Abstract: Upregulation of neuronal oxidative stress is involved in the progression of secondary brain injury (SBI) following intracerebral hemorrhage (ICH). In this study, we investigated the potential effects and underlying mechanisms of …
1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a New Anti-Proliferative Ellagitannin, Regulates the Expression of microRNAs in HepG(2) Cancer Cells.
PMID: Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct ;31(10):1641-8. PMID: 22027761 Abstract Title: 1,3,4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose, a new anti-proliferative ellagitannin, regulates the expression of microRNAs in HepG(2) cancer cells. Abstract: OBJECTIVE: MicroRNAs (miRNAs) play important roles in cell proliferation, differentiation and apoptosis. 1, 3, 4-tri-O-galloyl-6-O-caffeoyl-β-D-glucopyranose (BJA32515) is a new natural ellagitannin compound extracted from …
Recent studies have shown that natural agents including curcumin, isoflavone, indole-3-carbinol, 3,3′-diindolylmethane, (-)-epigallocatechin-3-gallate, resveratrol, etc. could alter miRNA expression profiles, leading to the inhibition of cancer cell growt
PMID: Pharm Res. 2010 Jun ;27(6):1027-41. Epub 2010 Mar 20. PMID: 20306121-regulation-of-micrornas-by-natural-agents-an-emerging-field-in-chemoprevention-and-chem Abstract Title: Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Abstract: In recent years, microRNAs have received greater attention in cancer research. These small, non-coding RNAs could inhibit target gene expression by binding to the 3' untranslated …
Antimicrobial mechanism of luteolin against Staphylococcus aureus and Listeria monocytogenes and its antibiofilm properties.
PMID: Microb Pathog. 2020 Feb 11 ;142:104056. Epub 2020 Feb 11. PMID: 32058023 Abstract Title: Antimicrobial mechanism of luteolin against Staphylococcus aureus and Listeria monocytogenes and its antibiofilm properties. Abstract: Luteolin (LUT) is a naturally occurring compound found in a various of plants. Few recent studies have reported LUT antimicrobial activities against bacterial pathogens, however, …
Luteolin suppresses teratoma cell growth and induces cell apoptosis via inhibiting Bcl-2.
PMID: Oncol Res. 2019 Jul 12 ;27(7):773-778. Epub 2018 Mar 14. PMID: 29540256 Abstract Title: Luteolin Suppresses Teratoma Cell Growth and Induces Cell Apoptosis via Inhibiting Bcl-2. Abstract: Luteolin, which is found in plant foods, has a range of therapeutic applications. In order to examine the potential roles of luteolin in ovarian teratocarcinoma, the human …
Lactobacillus probiotics improved the gut microbiota profile in an Alzheimer’s disease model and alleviated neurodegeneration in the eye.
PMID: Benef Microbes. 2020 Feb 19 ;11(1):79-89. Epub 2020 Jan 14. PMID: 32066253 Abstract Title: probiotics improved the gut microbiota profile of aAlzheimer's disease model and alleviated neurodegeneration in the eye. Abstract: Alzheimer's disease (AD) is a progressive disease and one of the most common forms of neurodegenerative disorders. Emerging evidence is supporting the use …
Probiotic BSH activity and anti-obesity potential of Lactobacillus plantarum strain TCI378 isolated from Korean Kimchi.
PMID: Prev Nutr Food Sci. 2019 Dec ;24(4):434-441. Epub 2019 Dec 31. PMID: 31915639 Abstract Title: Probiotic BSH Activity and Anti-Obesity Potential ofStrain TCI378 Isolated from Korean Kimchi. Abstract: (.) is a human probiotic beneficial for the prevention and improvement of disease, yet properties of differentstrains are diverse. To obtain astrain that possesses greater potential …
Probiotic properties and neuroprotective effects of Lactobacillus buchneri KU200793 isolated from Korean fermented foods.
PMID: Int J Mol Sci. 2020 Feb 12 ;21(4). Epub 2020 Feb 12. PMID: 32059401 Abstract Title: Probiotic Properties and Neuroprotective Effects ofKU200793 Isolated from Korean Fermented Foods. Abstract: The purpose of this study was to evaluate the probiotic characteristics and neuroprotective effects of bacteria isolated from Korean fermented foods. Three bacterial strains (KU200060,KU200171, andKU200793) …
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