Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons.

PMID:  Emerg Microbes Infect. 2019 ;8(1):307-326. PMID: 30866785 Abstract Title:  Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons. Abstract:  The harmful effects of ZIKA virus (ZIKV) infection are reflected by severe neurological manifestations such as microcephaly in neonates and other complications associated with Guillain-Barré syndrome in adults. The transmission dynamics of …

Exosomes modulate the viral replication and host immune responses in hepatitis B virus infection.

PMID:  Biomed Res Int. 2019 ;2019:2103943. Epub 2019 May 28. PMID: 31275965 Abstract Title:  Exosomes Modulate the Viral Replication and Host Immune Responses in HBV Infection. Abstract:  Although current diagnosis and treatment of hepatitis B virus (HBV) infection can maintain viral suppression, new therapies need to be invented to sustain off-treatment virologic suppression and reduce …

Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.

PMID:  Sci Adv. 2019 07 ;5(7):eaav3270. Epub 2019 Jul 17. PMID: 31328155 Abstract Title:  Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Abstract:  Lysosomal exocytosis is a ubiquitous process negatively regulated by neuraminidase 1 (NEU1), a sialidase mutated in the glycoprotein storage disease sialidosis. Inmice, excessive lysosomal exocytosis is …

The Social, Psychic and Health Challenges of the Coronavirus Crisis Explored [Video]

This article is copyrighted by GreenMedInfo LLC, 2020Visit our Re-post guidelines Sayer Ji appears on the Robert Phoenix show and breaks down the social, psychic and health challenges of the current lockdown and state of the Coronavirus crisis. Take action and join a community who cares about health freedom: https://www.standforhealthfreedom.com read more

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.

PMID:  PLoS Pathog. 2019 07 ;15(7):e1007907. Epub 2019 Jul 25. PMID: 31344124 Abstract Title:  Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. Abstract:  HIV infection has a profound effect on"bystander"cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors. Here we …

Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication

PMID:  J Biomed Sci. 2019 Aug 15 ;26(1):58. Epub 2019 Aug 15. PMID: 31416454 Abstract Title:  Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication. Abstract:  BACKGROUND: Multiple interplays between viral and host factors are involved in influenza virus replication and pathogenesis. Several small RNAs have recently emerged as important regulators of host response …

Pathogenic role of exosomes and microRNAs in HPV-mediated inflammation and cervical cancer.

PMID:  Int J Cancer. 2020 01 15 ;146(2):305-320. Epub 2019 Oct 31. PMID: 31566705 Abstract Title:  Pathogenic role of exosomes and microRNAs in HPV-mediated inflammation and cervical cancer: A review. Abstract:  Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most important risk factor for the development of CC …

Expression patterns of exosomal miRNAs are a promising tool to predict sustained viral response- hepatocellular carcinoma.

PMID:  Biomedicines. 2019 Nov 3 ;7(4). Epub 2019 Nov 3. PMID: 31684167 Abstract Title:  Circulating Exosomal miRNA Profiles Predict the Occurrence and Recurrence of Hepatocellular Carcinoma in Patients with Direct-Acting Antiviral-Induced Sustained Viral Response. Abstract:  Direct-acting antiviral (DAA) therapy for chronic hepatitis C virus (HCV) infection patients (CH) results in a sustained viral response (SVR) …

Dengue haemorrhagic fever: a job done via exosomes?

PMID:  Emerg Microbes Infect. 2019 ;8(1):1626-1635. PMID: 31711408 Abstract Title:  Dengue haemorrhagic fever: a job done via exosomes? Abstract:  Dengue fever is one of those unique diseases where host immune responses largely determine the pathogenesis and its severity. Earlier studies have established the fact that dengue virus (DENV) infection causes haemorrhagic fever and shock syndrome, …

CD81+ exosomes play a pivotal role in the establishment of hepatitis C persistent infection and contribute toward the progression of hepatocellular carcinoma.

PMID:  Viral Immunol. 2019 Dec ;32(10):453-462. Epub 2019 Nov 22. PMID: 31755827 Abstract Title:  CD81Exosomes Play a Pivotal Role in the Establishment of Hepatitis C Persistent Infection and Contribute Toward the Progression of Hepatocellular Carcinoma. Abstract:  CD81 serves as an immune modulator, playing its role in tumor growth and metastasis of hepatitis C virus (HCV)-mediated …

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