Author Archives: Taylor Mercado

PMID:  Aging (Albany NY). 2020 Feb 13 ;12. Epub 2020 Feb 13. PMID: 32062612 Abstract Title:  Berberine promotes XIAP-mediated cells apoptosis by upregulation of miR-24-3p in acute lymphoblastic leukemia. Abstract:  BACKGROUND: Berberine (BBR) has gained considerable attention because of its anti-tumor activity. BBR can induce apoptosis of acute lymphoblastic leukemia (ALL) cells through the MDM2/p53 …

Continue reading “Berberine promotes XIAP-mediated cells apoptosis by upregulation of miR-24-3p in acute lymphoblastic leukemia.”

PMID:  Front Pharmacol. 2019 ;10:1658. Epub 2020 Jan 29. PMID: 32063859 Abstract Title:  Berberine Maintains the Neutrophil N1 Phenotype to Reverse Cancer Cell Resistance to Doxorubicin. Abstract:  This study explores the contributions of neutrophils to chemotherapeutic resistance and berberine-regulated cancer cell sensitivity to doxorubicin (DOX).experiments, continuous DOX treatment led to the shift of HL-60 cells …

Continue reading “Berberine maintains the neutrophil N1 phenotype to reverse cancer cell resistance to doxorubicin.”

PMID:  Eur J Pharm Biopharm. 2020 Feb 14. Epub 2020 Feb 14. PMID: 32068029 Abstract Title:  Berberine encapsulated PEG-coated liposomes attenuate Wnt1/β-catenin signaling in rheumatoid arthritis via miR-23a activation. Abstract:  Bone erosion is a debilitating pathological process of osteopathic disorder like rheumatoid arthritis (RA). Current treatment strategies render low disease activity but with disease recurrence. …

Continue reading “Berberine encapsulated PEG-coated liposomes attenuate Wnt1/β-catenin signaling in rheumatoid arthritis via miR-23a activation.”

PMID:  Vascul Pharmacol. 2020 Feb 15:106660. Epub 2020 Feb 15. PMID: 32070767 Abstract Title:  Berberine protects Kawasaki disease-induced human coronary artery endothelial cells dysfunction by inhibiting of oxidative and endoplasmic reticulum stress. Abstract:  Kawasaki disease (KD) is an acute febrile illness characterized by systemic vasculitis especially in coronary arteries. Berberine (BBR) shows several beneficial effects …

Continue reading “Berberine protects Kawasaki disease-induced human coronary artery endothelial cells dysfunction.”

PMID:  Arch Physiol Biochem. 2020 Feb 19:1-12. Epub 2020 Feb 19. PMID: 32072839 Abstract Title:  Berberine alleviates monosodium glutamate induced postnatal metabolic disorders associated vascular endothelial dysfunction in newborn rats: possible role of matrix metalloproteinase-1. Abstract:  Excessive food additives Monosodium glutamate (MSG) results in metabolic disorders with increased Cardiovascular diseases CVD. We aimed to emphasise …

Continue reading “Berberine alleviates monosodium glutamate induced postnatal metabolic disorders associated vascular endothelial dysfunction.”

PMID:  Eur J Nutr. 2020 Feb 11. Epub 2020 Feb 11. PMID: 32048004 Abstract Title:  Whole mung bean (Vigna radiata L.) supplementation prevents high-fat diet-induced obesity and disorders in a lipid profile and modulates gut microbiota in mice. Abstract:  PURPOSE: Obesity, a strong risk factor for metabolic disorder, has become a major impediment for public …

Continue reading “Whole mung bean (Vigna radiata L.) supplementation prevents high-fat diet-induced obesity and disorders in a lipid profile.”

PMID:  J Invest Dermatol. 2020 Feb 5. Epub 2020 Feb 5. PMID: 32057839 Abstract Title:  Short-term exposure to a Western diet induces psoriasiform dermatitis by promoting accumulation of IL-17A-producingγδ T cells. Abstract:  A Western diet (WD)-characterized by its high fat and simple sugar content-is thought to predispose individuals to inflammatory skin diseases such as psoriasis, …

Continue reading “Short-term exposure to a Western diet induces psoriasiform dermatitis.”

PMID:  Pak J Pharm Sci. 2019 Nov ;32(6(Supplementary)):2859-2864. PMID: 32024625 Abstract Title:  Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals. Abstract:  Frozen food chemicals contain neurotoxins which disturb electrolyte levels. Altered electrolyte levels can induce mental illnesses. This study was focused on finding the prevalence of depression, dementia, intake …

Continue reading “Depression and dementia from hyponatremia in brain cancer patients exposed to frozen food chemicals.”

PMID:  Sci Rep. 2017 06 13 ;7(1):3398. Epub 2017 Jun 13. PMID: 28611391 Abstract Title:  Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint. Abstract:  Osteoarthritis is a major cause of disability and there is no current pharmaceutical treatment which can prevent the disease or …

Continue reading “Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint.”

PMID:  J Nutr Biochem. 2019 01 ;63:27-34. Epub 2018 Sep 21. PMID: 30317146 Abstract Title:  Broccoli consumption affects the human gastrointestinal microbiota. Abstract:  The human gastrointestinal microbiota is increasingly linked to health outcomes; however, our understanding of how specific foods alter the microbiota is limited. Cruciferous vegetables such as broccoli are a good source of …

Continue reading “Broccoli consumption affects the human gastrointestinal microbiota.”