Author Archives: Taylor Mercado

PMID:  Food Chem. 2019 Oct 1 ;294:477-485. Epub 2019 May 11. PMID: 31126490 Abstract Title:  Hydrolysis of radish anthocyanins to enhance the antioxidant and antiproliferative capacities. Abstract:  Radish anthocyanins were extracted from red radish. The total anthocyanins content (TAC) of the extracts under different extractants was optimized to reach the optimal condition. XAD-7HP was selected …

Continue reading “Hydrolysis of radish anthocyanins to enhance the antioxidant and antiproliferative capacities.”

PMID:  Nutr Cancer. 2019 Nov 25:1-12. Epub 2019 Nov 25. PMID: 31763931 Abstract Title:  L. seed extracts induce apoptosis and reduce migration of oral squamous cell carcinoma KB and KBcells by downregulation ofβ-catenin. Abstract:  Although, oral cancer therapies have been developed for decades, patient survival rates have not changed. Side effects of chemotherapy and radiotherapy …

Continue reading “Raphanus sativus L. seed extracts induce apoptosis and reduce migration of oral squamous cell carcinoma.”

PMID:  Food Chem Toxicol. 2020 Feb ;136:111050. Epub 2019 Dec 14. PMID: 31843533 Abstract Title:  Extraction and characterization of phenolic compounds with antioxidant and antimicrobial activities from pickled radish. Abstract:  The pickled radish can be kept at room temperature for years without spoilage. 2,6-dihydroxyacetophenone (DHAP), 4-hydroxybenzaldehyde (HBA), and 4-hydroxyphenethyl alcohol (4-HPEA) were first found from …

Continue reading “Extraction and characterization of phenolic compounds with antioxidant and antimicrobial activities from pickled radish.”

PMID:  Mol Nutr Food Res. 2010 Jan ;54(1):127-35. PMID: 19960458 Abstract Title:  Allyl isothiocyanate as a cancer chemopreventive phytochemical. Abstract:  Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, is widely and often frequently consumed by humans. Besides antimicrobial activity against a wide spectrum of pathogens, it showed anticancer activity in both cultured cancer …

Continue reading “Allyl isothiocyanate as a cancer chemopreventive phytochemical.”

PMID:  Oncol Rep. 2010 Aug ;24(2):449-55. PMID: 20596632 Abstract Title:  Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway. Abstract:  Isothiocyanates (ITCs) are present as glucosinolates in various cruciferous vegetables. Allyl isothiocyanate (AITC) is one of the common naturally occurring isothiocyanates. Recent studies have …

Continue reading “Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells.”

PMID:  Carcinogenesis. 2010 Dec ;31(12):2105-10. Epub 2010 Oct 1. PMID: 20889681 Abstract Title:  Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion. Abstract:  Allyl isothiocyanate (AITC), which occurs in many common cruciferous vegetables, was recently shown to be selectively delivered to bladder cancer tissues through urinary excretion and to inhibit bladder cancer …

Continue reading “Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion.”

PMID:  Mol Med Rep. 2010 Nov-Dec;3(6):1023-30. Epub 2010 Sep 15. PMID: 21472349 Abstract Title:  Allyl isothiocyanate induces G2/M arrest in human colorectal adenocarcinoma SW620 cells through down-regulation of Cdc25B and Cdc25C. Abstract:  Allyl isothiocyanate (AITC) is a constituent of cruciferous vegetables that exhibits antitumor activity. In this study, AITC was shown to inhibit the proliferation …

Continue reading “Allyl isothiocyanate induces G2/M arrest in human colorectal adenocarcinoma SW620 cells.”

PMID:  J Biol Chem. 2011 Sep 16 ;286(37):32259-67. Epub 2011 Jul 21. PMID: 21778226 Abstract Title:  Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation. Abstract:  Allyl isothiocyanate (AITC) occurs in many commonly consumed cruciferous vegetables and exhibits significant anti-cancer activities. Available data suggest that …

Continue reading “Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation.”

PMID:  Oncol Rep. 2014 Jan ;31(1):189-96. Epub 2013 Nov 20. PMID: 24270601 Abstract Title:  Allyl isothiocyanate inhibits cell metastasis through suppression of the MAPK pathways in epidermal growth factor‑stimulated HT29 human colorectal adenocarcinoma cells. Abstract:  Allyl isothiocyanate (AITC) has been found to present sources from consumed cruciferous vegetables. AITC is known to possess pharmacological and …

Continue reading “Allyl isothiocyanate may be beneficial in the treatment of human colorectal adenocarcinoma in the future.”

PMID:  Mutat Res. 2014 Apr ;762:40-6. Epub 2014 Mar 10. PMID: 24625788 Abstract Title:  Cell cycle kinetics, apoptosis rates, DNA damage and TP53 gene expression in bladder cancer cells treated with allyl isothiocyanate (mustard essential oil). Abstract:  Allyl isothiocyanate (AITC) is present in plants of the cruciferous family and is abundant in mustard seed. Due …

Continue reading “Cell cycle kinetics, apoptosis rates, DNA damage and TP53 gene expression in bladder cancer cells treated with allyl isothiocyanate.”