PMID: J Nutr Biochem. 2014 Oct ;25(10):1026-34. Epub 2014 Jun 5. PMID: 25034503 Abstract Title: Allyl isothiocyanate ameliorates insulin resistance through the regulation of mitochondrial function. Abstract: Mitochondrial dysfunction is associated with the pathophysiology of insulin resistance. Allylisothiocyanate (AITC) is found in many cruciferous vegetables and has been reported to possess anticancer activity. However, the …
Author Archives: Taylor Mercado
Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis.
PMID: PLoS One. 2014 ;9(7):e102975. Epub 2014 Jul 22. PMID: 25051185 Abstract Title: Allyl isothiocyanate ameliorates angiogenesis and inflammation in dextran sulfate sodium-induced acute colitis. Abstract: Allyl isothiocyanate (AITC) is a phytochemical found in cruciferous vegetables that has known chemopreventive and chemotherapeutic activities. Thus far, the antiangiogenic activity of AITC has not been reported in …
Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.
PMID: Am J Cancer Res. 2015 ;5(8):2516-30. Epub 2015 Jul 15. PMID: 26396928 Abstract Title: Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo. Abstract: Although in vitro studies have shown that isothiocyanates (ITCs) can synergistically sensitize cancer cells to cisplatin treatment, the underlying mechanisms have not been well defined, …
Allyl isothiocyanate induces cell toxicity by multiple pathways in human breast cancer cells.
PMID: Am J Chin Med. 2016 ;44(2):415-37. PMID: 27080949 Abstract Title: Allyl Isothiocyanate Induces Cell Toxicity by Multiple Pathways in Human Breast Cancer Cells. Abstract: Isothiocyanates (ITCs) occur in many cruciferous vegetables. These compounds, which have significant anticancer actions, can induce apoptosis in different human cancer cell lines. In the present study, we investigated if …
Hepatoprotective effects of allyl isothiocyanate against carbon tetrachloride-induced hepatotoxicity.
PMID: Chem Biol Interact. 2016 Jul 25 ;254:102-8. Epub 2016 May 27. PMID: 27241356 Abstract Title: Hepatoprotective effects of allyl isothiocyanate against carbon tetrachloride-induced hepatotoxicity in rat. Abstract: We evaluated the hepatoprotective activity of allyl isothiocyanate (AITC) against carbon tetrachloride (CCl4)-induced liver injury in rats. Sprague Dawley rats were orally administered AITC at doses of …
Allyl isothiocyanate inhibits the proliferation of renal carcinoma cell line GRC-1
PMID: Med Sci Monit. 2016 Nov 10 ;22:4283-4288. Epub 2016 Nov 10. PMID: 27834342 Abstract Title: Allyl Isothiocyanate Inhibits the Proliferation of Renal Carcinoma Cell Line GRC-1 by Inducing an Imbalance Between Bcl2 and Bax. Abstract: BACKGROUND Because of the insensitivity of renal cell carcinoma (RCC) to both chemotherapy and radiotherapy, surgery remains the primary …
Activity of allyl isothiocyanate and Its synergy with fluconazole against Candida albicans biofilms.
PMID: J Microbiol Biotechnol. 2017 Apr 28 ;27(4):685-693. PMID: 28138121 Abstract Title: Activity of Allyl Isothiocyanate and Its Synergy with Fluconazole againstBiofilms. Abstract: Candidiasis involving the biofilms ofis a threat to immunocompromised patients.biofilms are intrinsically resistant to the antifungal drugs and hence novel treatment strategies are desired. The study intended to evaluate the anti-activity of …
Parentectomy: The State-Driven Campaign to Remove Parents’ Rights
The time to stand for our civil and religious liberties, particularly parental rights, is now. Laws are being drafted with the intention of removing parents from vaccine decision-making
The result suggests that allyl isothiocyanate has anti-inflammatory potential to prevent DMBA- and MNU-induced mammary carcinogenesis.
PMID: Breast Cancer. 2018 Jan ;25(1):50-59. Epub 2017 May 13. PMID: 28501931 Abstract Title: Effect of allyl isothiocyanate on NF-κB signaling in 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea-induced mammary carcinogenesis. Abstract: BACKGROUND: Inflammation plays a pivotal role in the process of carcinogenesis and phytochemicals have anti-inflammatory properties gaining more importance in cancer chemoprevention. The present study aimed to …
Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis.
PMID: Mol Cell Biochem. 2018 Jan ;437(1-2):1-12. Epub 2017 Jun 5. PMID: 28585088 Abstract Title: Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis. Abstract: In the present study, we investigated the effect of allyl isothiocyanate (AITC) on liver detoxification signaling pathway in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinogenesis. Mammary tumor …
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