Author Archives: Taylor Mercado

PMID:  J Sci Food Agric. 2018 Jan ;98(2):792-798. Epub 2017 Aug 12. PMID: 28675475 Abstract Title:  Fumigation of Brazil nuts with allyl isothiocyanate to inhibit the growth of Aspergillus parasiticus and aflatoxin production. Abstract:  BACKGROUND: Brazil produces approximately 40 000 tons of Brazil nuts annually, which is commonly contaminated with fungi and mycotoxins. Gaseous allyl …

Continue reading “Fumigation of Brazil nuts with allyl isothiocyanate to inhibit the growth of Aspergillus parasiticus and aflatoxin production.”

PMID:  Mol Nutr Food Res. 2018 03 ;62(6):e1700616. Epub 2018 Mar 12. PMID: 29345776 Abstract Title:  Allyl Isothiocyanate Ameliorates Obesity by Inhibiting Galectin-12. Abstract:  SCOPE: The aim of this study is to investigate the signaling pathways by which allyl isothiocyanate (AITC) reduces adipocyte differentiation and the efficacy of AITC in suppressing galectin-12 levels as a …

Continue reading “Allyl isothiocyanate ameliorates obesity by inhibiting galectin-12.”

PMID:  J Vet Med Sci. 2018 Jun 6 ;80(6):893-897. Epub 2018 Apr 17. PMID: 29669958 Abstract Title:  Allyl isothiocyanate reduces liver fibrosis by regulating Kupffer cell activation in rats. Abstract:  Allyl isothiocyanate (AITC), a metabolite of the glucosinolate sinigrin, protects the liver of rats injured by carbon tetrachloride (CCl). This study evaluated whether AITC reduces …

Continue reading “Allyl isothiocyanate reduces liver fibrosis by regulating Kupffer cell activation.”

PMID:  Oncol Lett. 2018 Jun ;15(6):8756-8760. Epub 2018 Apr 4. PMID: 29805614 Abstract Title:  Effect of allyl isothiocyanate on the viability and apoptosis of the human cervical cancer HeLa cell line. Abstract:  The present study aimed to investigate the effect of allyl isothiocyanate (AITC) on the viability and apoptosis of the human cervical cancer HeLa …

Continue reading “Effect of allyl isothiocyanate on the viability and apoptosis of the human cervical cancer HeLa cell line in vitro.”

PMID:  Int J Mol Sci. 2018 Jul 12 ;19(7). Epub 2018 Jul 12. PMID: 30002285 Abstract Title:  Allyl Isothiocyanate Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mouse by Enhancing Tight Junction and Mucin Expression. Abstract:  Inflammatory bowel disease (IBD) is characterized by chronic or recurrent inflammation of the gastrointestinal tract. Even though the current strategies to …

Continue reading “Allyl isothiocyanate ameliorates dextran sodium sulfate-induced colitis.”

PMID:  Am J Chin Med. 2018 Oct 4:1-19. Epub 2018 Oct 4. PMID: 30284468 Abstract Title:  Allyl Isothiocyanate Induces Autophagy through the Up-Regulation of Beclin-1 in Human Prostate Cancer Cells. Abstract:  Allyl isothiocyanate (AITC), one of the most widely studied phytochemicals, inhibits the survival of human prostate cancer cells while minimally affecting normal prostate epithelial …

Continue reading “Allyl isothiocyanate induces autophagy through the up-regulation of beclin-1 in human prostate cancer cells.”

PMID:  Mol Biol Rep. 2019 Feb ;46(1):241-250. Epub 2018 Nov 8. PMID: 30406889 Abstract Title:  Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury in mice. Abstract:  Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in young adults and children in the industrialized …

Continue reading “Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury.”

PMID:  J Sci Food Agric. 2019 Apr ;99(6):3106-3116. Epub 2019 Jan 25. PMID: 30516283 Abstract Title:  Preparation of allyl isothiocyanate nanoparticles, their anti-inflammatory activity towards RAW 264.7 macrophage cells and anti-proliferative effect on HT1376 bladder cancer cells. Abstract:  BACKGROUND: Allyl isothiocyanate (AITC), a volatile and water-insoluble compound present in several cruciferous vegetables, has been shown …

Continue reading “Allyl isothiocyanate nanoparticles have potential as therapeutic agents for bladder cancer and the enhancement of immune function.”

PMID:  Pathol Oncol Res. 2019 Mar 20. Epub 2019 Mar 20. PMID: 30895454 Abstract Title:  Anti-Estrogenic and Anti-Cell Proliferative Effect of Allyl Isothiocyanate in Chemoprevention of Chemically Induced Mammary Carcinogenesis in Rats. Abstract:  The anti-estrogenic and anti-cell proliferative effect of allyl isothiocyanate (AITC) was carried out by analyzing the status of sex hormones and its …

Continue reading “Anti-estrogenic and anti-cell proliferative effect of allyl isothiocyanate in chemoprevention of chemically induced mammary carcinogenesis.”

PMID:  J Biochem Mol Toxicol. 2019 Jul ;33(7):e22328. Epub 2019 Mar 30. PMID: 30927557 Abstract Title:  Effects of allyl isothiocyanate on insulin resistance, oxidative stress status, and transcription factors in high-fat diet/streptozotocin-induced type 2 diabetes mellitus in rats. Abstract:  Allyl isothiocyanate (AITC), a dietary phytochemical found in some cruciferous vegetables, is commonly used as an antimicrobial, …

Continue reading “Allyl isothiocyanate possesses antidiabetic, antioxidant, and anti-inflammatory activities in high-fat diet/streptozotocin-induced type 2 diabetes mellitus.”