PMID: Am J Respir Cell Mol Biol. 2011 Feb ;44(2):197-204. Epub 2010 Apr 8. PMID: 20378751 Abstract Title: Particulate matter induces translocation of IL-6 from the lung to the systemic circulation. Abstract: The biological mechanisms responsible for an association between elevated concentrations of ambient particulate matter (PM) and increased cardiovascular morbidity and mortality remain unclear. …
Author Archives: Taylor Mercado
Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae.
PMID: Infect Immun. 2010 Mar ;78(3):1214-20. Epub 2009 Dec 14. PMID: 20008540 Abstract Title: Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae. Abstract: Cigarette smoke exposure increases the risk of pulmonary and invasive infections caused by Streptococcus pneumoniae, the most commonly isolated organism from patients with community-acquired pneumonia. …
Fine particulate matter-induced exacerbation of allergic asthma via activation of T-cell immunoglobulin and mucin domain 1.
PMID: Chin Med J (Engl). 2018 Oct 20 ;131(20):2461-2473. PMID: 30334531 Abstract Title: Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1. Abstract: Background: Fine particulate matter (PM) exacerbates airway inflammation and hyperreactivity in patients with asthma, but the mechanism remains unclear. The aim of this study was …
Fine particulate matter (PM2.5) enhances allergic sensitization in BALB/c mice
PMID: J Toxicol Environ Health A. 2017 ;80(4):197-207. Epub 2017 May 11. PMID: 28494199 Abstract Title: Fine particulate matter (PM) enhances allergic sensitization in BALB/c mice. Abstract: Ambient particulate matter (PM), a component of air pollution, exacerbates airway inflammation and hyperreactivity in asthmatic patients. Studies showed that PM possesses adjuvant-like properties that enhance the allergic …
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The acute pulmonary toxicity in mice induced by Staphylococcus aureus, particulate matter, and their combination.
PMID: Exp Anim. 2019 May 8 ;68(2):159-168. Epub 2018 Dec 10. PMID: 30531117 Abstract Title: The acute pulmonary toxicity in mice induced by Staphylococcus aureus, particulate matter, and their combination. Abstract: Inhalation of pathogenic bacteria transported by particulate matter (PM) presents an important potential threat to human health. Therefore, the pulmonary toxicity in mice caused …
NLRP3 inflammasome activation and lung fibrosis caused by airborne fine particulate matter.
PMID: Ecotoxicol Environ Saf. 2018 Nov 15 ;163:612-619. Epub 2018 Aug 6. PMID: 30092543 Abstract Title: NLRP3 inflammasome activation and lung fibrosis caused by airborne fine particulate matter. Abstract: Airborne fine particulate matter (PM) has been known capable of causing lung inflammation and fibrosis, as a result of a series of chronic respiration diseases. Although …
At seeming safe concentrations, synergistic effects of PM2.5 and formaldehyde co-exposure induces Alzheimer-like changes in mouse brain.
PMID: Oncotarget. 2017 Nov 17 ;8(58):98567-98579. Epub 2017 Oct 6. PMID: 29228711 Abstract Title: At seeming safe concentrations, synergistic effects of PMand formaldehyde co-exposure induces Alzheimer-like changes in mouse brain. Abstract: Alzheimer's disease (AD) is a serious, common, global disease, yet its etiology and pathogenesis are incompletely understood. Air pollution is a multi-pollutants co-exposure system, …
Vitamin E reduces the extent of mouse brain damage induced by combined exposure to formaldehyde and PM2.5.
PMID: Ecotoxicol Environ Saf. 2019 May 15 ;172:33-39. Epub 2019 Jan 19. PMID: 30669072 Abstract Title: Vitamin E reduces the extent of mouse brain damage induced by combined exposure to formaldehyde and PM2.5. Abstract: Exposure to specific air pollutants has been demonstrated to induce damage in the brain. However, these studies ignore the effects of …
The results also indicated that the nutritional supplementation might be an effective way to protecting people’s health from air pollution.
PMID: Environ Sci Pollut Res Int. 2018 Aug ;25(22):22153-22162. Epub 2018 May 26. PMID: 29804245 Abstract Title: The protective effects of selenium supplementation on ambient PMinduced cardiovascular injury in rats. Abstract: Substantial epidemiological and experimental studies have shown that ambient fine particulate matter (PM) exposure can lead to myocardial damage in human and animal through …
Supplementation with vitamin E and omega-3 polyunsaturated fatty acids could protect the particulate matter-induced injury.
PMID: Chemosphere. 2017 Apr ;173:14-21. Epub 2017 Jan 8. PMID: 28104476 Abstract Title: Combined effects of vitamin E and omega-3 fatty acids on protecting ambient PM-induced cardiovascular injury in rats. Abstract: OBJECTIVE: This study aims to observe whether the combined treatment with vitamin E (vit E) and omega-3 polyunsaturated fatty acids (Ω-3 FA) could prevent …
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