PMID: Antioxidants (Basel). 2020 Jan 6 ;9(1). Epub 2020 Jan 6. PMID: 31935828 Abstract Title: Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson's Disease: A Comparative Study. Abstract: We compared the neuroprotective action of three natural bio-antioxidants (AOs): ellagic acid (EA),α-lipoic acid (LA), and myrtenal (Myrt) in an experimental model of …
Author Archives: Taylor Mercado
Gamma tocopherol reduced chemotherapeutic-induced ROS in an ovarian granulosa cell line.
PMID: Antioxidants (Basel). 2020 Jan 7 ;9(1). Epub 2020 Jan 7. PMID: 31936058 Abstract Title: Gamma Tocopherol Reduced Chemotherapeutic-Induced ROS in an Ovarian Granulosa Cell Line, But Not in Breast Cancer Cell Lines In Vitro. Abstract: Doxorubicin and cyclophosphamide are used to treat breast cancer, but they also cause infertility through off-target cytotoxicity towards proliferating …
Oxidative stress and cancer: chemopreventive and therapeutic role of triphala.
PMID: Antioxidants (Basel). 2020 Jan 13 ;9(1). Epub 2020 Jan 13. PMID: 31941067 Abstract Title: Oxidative Stress and Cancer: Chemopreventive and Therapeutic Role of Triphala. Abstract: Oxidative stress, caused by the overproduction of free radicals, leads to the development of many chronic diseases including cancer. Free radicals are known to damage cellular biomolecules like lipids, …
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Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures.
PMID: Sci Rep. 2020 Feb 14 ;10(1):2687. Epub 2020 Feb 14. PMID: 32060308 Abstract Title: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures. Abstract: Radiotherapy combined with chemotherapy is the major treatment modality for human glioblastoma multiforme (GBM). GBMs eventually relapse after treatment and the average survival of …
Protective effect of Schisandra chinensis bee pollen extract on liver and kidney injury induced by cisplatin in rats.
PMID: Biomed Pharmacother. 2017 Nov ;95:1765-1776. Epub 2017 Oct 6. PMID: 28962082 Abstract Title: Protective effect of Schisandra chinensis bee pollen extract on liver and kidney injury induced by cisplatin in rats. Abstract: Cisplatin (CP) has been used to cure numerous forms of cancers effectively in clinics, however, it could induce some toxic effects. Bee …
Neuroprotective and antioxidant effect of naringenin-loaded nanoparticles for nose-to-brain delivery.
PMID: Brain Sci. 2019 Oct 15 ;9(10). Epub 2019 Oct 15. PMID: 31618942 Abstract Title: Neuroprotective and Antioxidant Effect of Naringenin-Loaded Nanoparticles for Nose-to-Brain Delivery. Abstract: Parkinson's disease (PD) is a neurodegenerative disorder resulting in a decreased nigrostriatal availability of dopamine. Oxidative stress is one factor contributing to PD. Naringenin (NAR), a flavonoid, is a …
Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl4-induced hepatotoxicity
PMID: Exp Ther Med. 2020 Feb ;19(2):1313-1321. Epub 2019 Dec 19. PMID: 32010304 Abstract Title: Antioxidant, anti-inflammatory and anti-fibrotic effects ofgum resin in CCl-induced hepatotoxicity. Abstract: The present study aims to investigate the potential antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate (BS) gum resin against carbon tetrachloride (CCl)-induced liver damage. Four groups consisting of …
Silymarin suppresses HepG2 hepatocarcinoma cell progression.
PMID: Pharmacol Rep. 2020 Feb ;72(1):199-207. Epub 2020 Jan 8. PMID: 32016841 Abstract Title: Silymarin suppresses HepG2 hepatocarcinoma cell progression through downregulation of Slit-2/Robo-1 pathway. Abstract: BACKGROUND: 14 million people are diagnosed with new cancer and approximately 8 million people die from cancer every year. Hepatocellular carcinoma is the most common type of liver cancer …
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Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death.
PMID: J Pharm Pharmacol. 2020 Jan 10. Epub 2020 Jan 10. PMID: 31922618 Abstract Title: Natural polyphenols prevent indomethacin-induced and diclofenac-induced Caco-2 cell death by reducing endoplasmic reticulum stress regardless of their direct reactive oxygen species scavenging capacity. Abstract: OBJECTIVES: Indomethacin (INDO) and diclofenac (DIC) can induce intestinal cell death through induction of oxidative stress-mediated …
Naringenin potentiated β-sitosterol healing effect on the scratch wound assay.
PMID: Res Pharm Sci. 2019 Dec ;14(6):566-573. Epub 2019 Dec 11. PMID: 32038736 Abstract Title: Naringenin potentiatedβ-sitosterol healing effect on the scratch wound assay. Abstract: In the present investigation scratch wound assay was used to study the ability of several combinations of each flavonoid (chrysin, naringenin or resveratrol) withβ-sitosterol to heal wounds. MTT test was …
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