PMID: Pharmacol Res. 2020 Feb 11:104690. Epub 2020 Feb 11. PMID: 32057894 Abstract Title: Berberine-mediated up-regulation of surfactant protein D facilitates cartilage repair by modulating immune responses via the inhibition of TLR4/NF-ĸB signaling. Abstract: The innate immune system drives inflammatory joint damage in osteoarthritis (OA) and regulates cartilage repair. Berberine chloride (BBR) is an isoquinoline …
Author Archives: Taylor Mercado
Anti-tumor and immunoregulatory effects of fermented papaya preparation.
PMID: Asian Pac J Cancer Prev. 2016 ;17(7):3077-84. PMID: 27509932 Abstract Title: AntiTumor and Immunoregulatory Effects of Fermented Papaya Preparation (FPP: SAIDOPS501). Abstract: Various beneficial effects have been described for fermented papaya preparation (FPP: SAIDOPS501) based on its antioxidative and antiinflammatory functions. The present study was designed to determine the effects of FPP on carcinogenesis …
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Neuroprotective effect of fermented papaya preparation by activation of Nrf2 pathway in astrocytes.
PMID: Nutr Neurosci. 2018 Apr ;21(3):176-184. Epub 2016 Nov 14. PMID: 27841081 Abstract Title: Neuroprotective effect of fermented papaya preparation by activation of Nrf2 pathway in astrocytes. Abstract: OBJECTIVES: Nuclear factor erythroid 2-related factor (Nrf2) in astrocyte plays important roles in brain homeostasis. Fermented papaya preparation (FPP) has anti-oxidative, anti-inflammatory, immunoregulatory properties. The present study …
Oral administration of fermented papaya controls the growth of a murine melanoma.
PMID: Cancers (Basel). 2019 Jan 20 ;11(1). Epub 2019 Jan 20. PMID: 30669508 Abstract Title: Oral Administration of Fermented Papaya (FPP) Controls the Growth of a Murine Melanoma through the In Vivo Induction of a Natural Antioxidant Response. Abstract: Prolonged oxidative stress may play a key role in tumor development. Antioxidant molecules are contained in …
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Beneficial effects of fermented papaya preparation supplementation on redox balance and aging.
PMID: Antioxidants (Basel). 2020 Feb 7 ;9(2). Epub 2020 Feb 7. PMID: 32046112 Abstract Title: Beneficial Effects of Fermented Papaya Preparation (FPP) Supplementation on Redox Balance and Aging in a Mouse Model. Abstract: In recent decades much attention has been paid to how dietary antioxidants may positively affect the human health, including the beneficial effects …
These findings emphasize that sugar-sweetened beverage intake is positively associated with C-reactive protein levels.
PMID: Int J Public Health. 2020 Jan ;65(1):45-53. Epub 2020 Jan 25. PMID: 31982934 Abstract Title: The association between sugar-sweetened beverages intake, body mass index, and inflammation in US adults. Abstract: OBJECTIVES: This study aims to (1) assess the associations between sugar-sweetened beverages (SSB) consumption and C-reactive protein (CRP) levels, and (2) evaluate the modifying …
Daily consumption of sugar-sweetened beverages lead to metabolic impairment and weight gain and may contribute to development of metabolic diseases.
PMID: J Obes Metab Syndr. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32045514 Abstract Title: Three-Month Daily Consumption of Sugar-Sweetened Beverages Affects the Liver, Adipose Tissue, and Glucose Metabolism. Abstract: Background: Growing evidence suggests links between sugar-sweetened beverages (SSBs) and metabolic disorders. We investigated the effects of SSBs commonly consumed by adolescents and their …
A proanthocyanidin dimer from Camellia ptilophylla modulated obesity and adipose tissue inflammation in high-fat diet.
PMID: Mol Nutr Food Res. 2019 06 ;63(11):e1900082. Epub 2019 Apr 3. PMID: 30893514 Abstract Title: GC-(4→8)-GCG, A Proanthocyanidin Dimer from Camellia ptilophylla, Modulates Obesity and Adipose Tissue Inflammation in High-Fat Diet Induced Obese Mice. Abstract: SCOPE: Excessive fat accumulation in adipose tissue leads to obesity and related chronic inflammation. This study aims to examine …
Cocoa tea induces mitochondria-dependent apoptosis in HCT116 cells.
PMID: Food Res Int. 2020 Mar ;129:108854. Epub 2019 Dec 2. PMID: 32036895 Abstract Title: Cocoa tea (Camellia ptilophylla) induces mitochondria-dependent apoptosis in HCT116 cells via ROS generation and PI3K/Akt signaling pathway. Abstract: Cocoa tea (Camellia ptilophylla), a natural gallocatechin gallate (GCG)-rich and low caffeine-containing tea species, has been recently reported to possess various bioactivities. …
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Delivery of apoptosis-inducing piperine to triple-negative breast cancer cells via Co-polymeric nanoparticles.
PMID: Anticancer Res. 2020 Feb ;40(2):689-694. PMID: 32014909 Abstract Title: Delivery of Apoptosis-inducing Piperine to Triple-negative Breast Cancer CellsCo-polymeric Nanoparticles. Abstract: BACKGROUND/AIM: Piperine, a major alkaloid of the fruit of black pepper plants, selectively inhibits the growth of triple-negative breast cancer cells but its lipophilicity restricts possible clinical application. This study therefore determined the feasibility …
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