PMID: Biomed Khim. 2018 Mar ;64(2):188-194. PMID: 29723149 Abstract Title: [Evaluation of the cardioprotective effect of ubiquinol on the model of reperfusion injury of rat myocardium]. Abstract: The cardioprotective effect of ubiquinol on the model of myocardium reperfusion injury in rats was investigated. The study was carried out using mature males of outbred rats. Myocardial …
Author Archives: Taylor Mercado
Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes.
PMID: Redox Rep. 2018 Dec ;23(1):136-145. PMID: 29734881 Abstract Title: Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes. Abstract: OBJECTIVES: Physical exercise significantly impacts the biochemistry of the organism. Ubiquinone is a key component of the mitochondrial respiratory chain and ubiquinol, its reduced and active form, is …
Oral intake of liquid ubiquinol might benefit type 2 diabetes patients by increasing antioxidant enzyme activity levels
PMID: Br J Nutr. 2018 07 ;120(1):57-63. PMID: 29936921 Abstract Title: Effect of liquid ubiquinol supplementation on glucose, lipids and antioxidant capacity in type 2 diabetes patients: a double-blind, randomised, placebo-controlled trial. Abstract: Ubiquinone is a lipid antioxidant, and a novel liquid ubiquinol (a hydro-soluble, reduced form of coenzyme Q10) supplement was recently developed. The …
Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration.
PMID: Biochem Biophys Res Commun. 2018 09 18 ;503(4):2639-2645. Epub 2018 Aug 11. PMID: 30107910 Abstract Title: Ubiquinol promotes retinal ganglion cell survival and blocks the apoptotic pathway in ischemic retinal degeneration. Abstract: Coenzyme Q10 (CoQ) protects retinal ganglion cells (RGCs) in experimental retinal ischemia and glaucoma by scavenging reactive oxygen species. We tested whether …
A pilot clinical study of liquid ubiquinol supplementation on cardiac function in pediatric dilated cardiomyopathy.
PMID: Nutrients. 2018 Nov 7 ;10(11). Epub 2018 Nov 7. PMID: 30405022 Abstract Title: A Pilot Clinical Study of Liquid Ubiquinol Supplementation on Cardiac Function in Pediatric Dilated Cardiomyopathy. Abstract: BACKGROUND: Pediatric dilated cardiomyopathy (PDCM) is a life-threatening type of cardiac muscle dysfunction in children. Ubiquinone is a lipid-soluble nutrient that participates in energy synthesis. …
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
PMID: J Bioenerg Biomembr. 2019 Dec ;51(6):393-402. Epub 2019 Nov 25. PMID: 31768722 Abstract Title: Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury. Abstract: The effects of hydrogen-rich water on oxidative stress via the Nrf2/ARE signaling pathway were studied in rats with myocardial ischemia-reperfusion injury (MIRI). Sixty rats …
Protective effects of hydrogen-rich water against cartilage damage in a model of osteoarthritis.
PMID: Med Sci Monit. 2020 Jan 12 ;26:e920211. Epub 2020 Jan 12. PMID: 31927559 Abstract Title: Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. Abstract: BACKGROUND The aim of this study was to investigate the mechanisms underlying the potential effects of …
Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway.
PMID: BMC Cancer. 2020 Jan 10 ;20(1):28. Epub 2020 Jan 10. PMID: 31924176 Abstract Title: Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. Abstract: BACKGROUND: Pyroptosis belongs to a novel inflammatory programmed cell death pathway, with the possible prognosis of endometrial cancer related to the terminal protein GSDMD. Hydrogen exerts a biphasic effect …
Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.
PMID: J Biochem Mol Toxicol. 2020 Feb 10:e22467. Epub 2020 Feb 10. PMID: 32040235 Abstract Title: Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway. Abstract: Oxidative stress induced by long-term cyclosporine A (CsA) administration is a major cause of chronic nephrotoxicity, which is characterized by tubular atrophy, tubular cell apoptosis, and interstitial fibrosis …
A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats.
PMID: Can J Physiol Pharmacol. 2020 Jan ;98(1):29-34. Epub 2019 Sep 19. PMID: 31536712 Abstract Title: A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. Abstract: Mitochondria are the major source of cellular energy metabolism. In the cardiac cells, mitochondria produce by way of the oxidative phosphorylation more …
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