Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men.

PMID:  Food Funct. 2018 Nov 14 ;9(11):5653-5659. PMID: 30302465 Abstract Title:  Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men. Abstract:  Coenzyme Q10 (CoQ10) exerts its functions in the body through the ability of its benzoquinone head group to accept and donate electrons. The primary functions are to relay electrons for …

Supplementation with selenium and coenzyme Q10 in critically ill patients.

n/a PMID:  Br J Hosp Med (Lond). 2019 Oct 2 ;80(10):589-593. PMID: 31589506 Abstract Title:  Supplementation with selenium and coenzyme Q10 in critically ill patients. Abstract:  Multiple organ dysfunction and resultant mortality in critically ill patients has been linked with impaired cellular energy supply and oxidative stress. Clinical studies supplementing selenium, on the basis of …

Coenzyme Q10 add-on metformin therapy improves endothelial dysfunction and inflammatory changes in patients with T2DM.

PMID:  J Lab Physicians. 2019 Oct-Dec;11(4):317-322. PMID: 31929697 Abstract Title:  Endothelial dysfunction and inflammatory biomarkers as a response factor of concurrent coenzyme Q10 add-on metformin in patients with type 2 diabetes mellitus. Abstract:  OBJECTIVES: The objective of the study was to evaluate the effect of metformin alone or in combination with coenzyme Q10 (CoQ10) on …

Possible antioxidant mechanism of coenzyme Q10 in diabetes.

PMID:  Res Pharm Sci. 2019 Dec ;14(6):524-533. Epub 2019 Dec 11. PMID: 32038732 Abstract Title:  Possible antioxidant mechanism of coenzyme Q10 in diabetes: impact on Sirt1/Nrf2 signaling pathways. Abstract:  Oxidative stress is a major complication in diabetes mellitus. The aim of this study was to investigate potential antioxidant activity of coenzyme Q10 (Co Q10) against …

Beneficial effects of curcumin supplementation were observed in decreasing disease activity scores and severity of cirrhosis in patients with cirrhosis.

PMID:  Phytother Res. 2020 Feb 3. Epub 2020 Feb 3. PMID: 32017253 Abstract Title:  Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: A randomized controlled trial. Abstract:  Recent reports indicated that curcumin had beneficial effects in animal models of liver injury and cirrhosis. Current study aimed to investigate the effects of …

Turmeric extract reduces the incidence and severity of radiation-induced mucositis.

PMID:  J Laryngol Otol. 2020 Feb 7:1-6. Epub 2020 Feb 7. PMID: 32029014 Abstract Title:  Role of turmeric extract in minimising mucositis in patients receiving radiotherapy for head and neck squamous cell cancer: a randomised, placebo-controlled trial. Abstract:  OBJECTIVE: To determine the role of turmeric extract in reducing mucositis in patients undergoing radiotherapy for head …

Curcumin may be an alternative therapy for improving the outcomes of Benzo(a)pyrene-induced lung injury.

PMID:  Molecules. 2020 Feb 7 ;25(3). Epub 2020 Feb 7. PMID: 32046055 Abstract Title:  Curcumin, an Active Constituent of Turmeric Spice: Implication in the Prevention of Lung Injury Induced by Benzo(a) Pyrene (BaP) in Rats. Abstract:  Benzo(a)pyrene (BaP) is a well-known carcinogen and enhances oxidative stress and apoptosis and also alters several molecular pathways. Curcumin …

Mechanisms of PKC-mediated enhancement of HIF-1α activity and its inhibition by vitamin K2 in hepatocellular carcinoma cells.

PMID:  Int J Mol Sci. 2019 Feb 26 ;20(5). Epub 2019 Feb 26. PMID: 30813635 Abstract Title:  Mechanisms of PKC-Mediated Enhancement of HIF-1α Activity and its Inhibition by Vitamin K2 in Hepatocellular Carcinoma Cells. Abstract:  Hypoxia-inducible factor 1 (HIF-1) plays important roles in cancer cell biology. HIF-1α is reportedly activated by several factors, including protein …

Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis.

PMID:  Int J Vitam Nutr Res. 2020 Jan ;90(1-2):42-48. Epub 2019 Feb 28. PMID: 30816822 Abstract Title:  Maximal dose-response of vitamin-K2 (menaquinone-4) on undercarboxylated osteocalcin in women with osteoporosis. Abstract:  Low concentrations of serum vitamin K accompany high concentrations of undercarboxylated osteocalcin (ucOC) and osteoporotic fractures. Although vitamin K2 (MK-4) is approved as a therapeutic …

Protective effects of vitamin K2 on 6-OHDA-induced apoptosis in PC12 cells through modulation bax and caspase-3 activation.

PMID:  Mol Biol Rep. 2019 Dec ;46(6):5777-5783. Epub 2019 Aug 7. PMID: 31392537 Abstract Title:  Protective effects of vitamin K2 on 6-OHDA-induced apoptosis in PC12 cells through modulation bax and caspase-3 activation. Abstract:  Neuroprotection using compounds with dual functions of anti-apoptotic and antioxidant effects fight against neurodegeneration. Vitamin K2 acts as a cofactor in many …

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