PMID: Nat Prod Res. 2018 Oct 22:1-4. Epub 2018 Oct 22. PMID: 30345819 Abstract Title: Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease. Abstract: Licochalcone B (LCB), an extract from the root of Glycyrrhiza inflate, has the same caffeic acid scaffold as curcumin (Cur), which …
Author Archives: Taylor Mercado
Ursolic acid is a potential anticancer compound for breast cancer therapy.
PMID: Crit Rev Food Sci Nutr. 2018 Mar 4 ;58(4):568-574. Epub 2017 Oct 4. PMID: 27469428 Abstract Title: Ursolic acid, a potential anticancer compound for breast cancer therapy. Abstract: There are growing interests in the health benefits associated with consumption of fruits and vegetables, especially for the prevention of cancer, cardiovascular, or other chronic diseases. …
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Antimicrobial and antibiofilm activities of ursolic acid against carbapenem-resistant Klebsiella pneumoniae.
PMID: J Antibiot (Tokyo). 2020 Feb 12. Epub 2020 Feb 12. PMID: 32051569 Abstract Title: Antimicrobial and antibiofilm activities of ursolic acid against carbapenem-resistant Klebsiella pneumoniae. Abstract: Previous studies demonstrated that ursolic acid (UA) present in apple pomace displays antimicrobial activity against some microorganisms, but the underlying mechanisms associated with this activity remain unexplored. Furthermore, …
Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model.
PMID: Biomaterials. 2020 Jan 31 ;238:119828. Epub 2020 Jan 31. PMID: 32045781 Abstract Title: Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model. Abstract: Magnesium (Mg)-based biometal attracts clinical applications due to its biodegradability and beneficial biological effects on tissue regeneration, especially in orthopaedics, yet the underlying anabolic mechanisms in relevant clinical …
Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.
PMID: Bioorg Med Chem Lett. 2011 Jan 1 ;21(1):294-8. Epub 2010 Nov 5. PMID: 21123068 Abstract Title: Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata. Abstract: The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine influenza (novel influenza), represents a serious threat to global human health. …
Withania somnifera extract enhances energy expenditure via improving mitochondrial function in adipose tissue and skeletal muscle.
PMID: Nutrients. 2020 Feb 7 ;12(2). Epub 2020 Feb 7. PMID: 32046183 Abstract Title: Extract Enhances Energy Expenditure via Improving Mitochondrial Function in Adipose Tissue and Skeletal Muscle. Abstract: Withania somnifera (WS), commonly known as ashwagandha, possesses diverse biological functions. WS root has mainly been used as an herbal medicine to treat anxiety and was …
Licocalchone-C extracted from Glycyrrhiza glabra inhibits lipopolysaccharide-interferon-γ inflammation.
PMID: Molecules. 2011 Jul 6 ;16(7):5720-34. Epub 2011 Jul 6. PMID: 21734629 Abstract Title: Licocalchone-C extracted from Glycyrrhiza glabra inhibits lipopolysaccharide-interferon-γ inflammation by improving antioxidant conditions and regulating inducible nitric oxide synthase expression. Abstract: The genus Glycyrrhiza consists of about 30 species, amoung these, G. glabra is the source of several phenolic compounds, known as …
Curcuminoids Reduce Symptoms of Ulcerative Colitis and Improve Well-Being
A simple natural food supplement has been shown to significantly enhance well-being and reduce the difficulty of bathroom urgency that often comes along with ulcerative colitis
Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin.
PMID: J Microbiol Biotechnol. 2012 Jun ;22(6):800-5. PMID: 22573157 Abstract Title: Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin. Abstract: Licochalcone E was firstly isolated from licorice root in 2005, which belongs to the retrochalcone family. Studies on the biological activities of licochalcone E were in …
Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.
PMID: Cancer Prev Res (Phila). 2013 Jun ;6(6):603-13. Epub 2013 Apr 26. PMID: 23625311 Abstract Title: Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model. Abstract: We investigated whether licochalcone E (LicE), a phenolic constituent of licorice, inhibits mammary tumor growth and metastasis using animal and cell culture models. …