Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer’s disease.

PMID:  Nat Prod Res. 2018 Oct 22:1-4. Epub 2018 Oct 22. PMID: 30345819 Abstract Title:  Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease. Abstract:  Licochalcone B (LCB), an extract from the root of Glycyrrhiza inflate, has the same caffeic acid scaffold as curcumin (Cur), which …

Ursolic acid is a potential anticancer compound for breast cancer therapy.

PMID:  Crit Rev Food Sci Nutr. 2018 Mar 4 ;58(4):568-574. Epub 2017 Oct 4. PMID: 27469428 Abstract Title:  Ursolic acid, a potential anticancer compound for breast cancer therapy. Abstract:  There are growing interests in the health benefits associated with consumption of fruits and vegetables, especially for the prevention of cancer, cardiovascular, or other chronic diseases. …

Antimicrobial and antibiofilm activities of ursolic acid against carbapenem-resistant Klebsiella pneumoniae.

PMID:  J Antibiot (Tokyo). 2020 Feb 12. Epub 2020 Feb 12. PMID: 32051569 Abstract Title:  Antimicrobial and antibiofilm activities of ursolic acid against carbapenem-resistant Klebsiella pneumoniae. Abstract:  Previous studies demonstrated that ursolic acid (UA) present in apple pomace displays antimicrobial activity against some microorganisms, but the underlying mechanisms associated with this activity remain unexplored. Furthermore, …

Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model.

PMID:  Biomaterials. 2020 Jan 31 ;238:119828. Epub 2020 Jan 31. PMID: 32045781 Abstract Title:  Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model. Abstract:  Magnesium (Mg)-based biometal attracts clinical applications due to its biodegradability and beneficial biological effects on tissue regeneration, especially in orthopaedics, yet the underlying anabolic mechanisms in relevant clinical …

Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.

PMID:  Bioorg Med Chem Lett. 2011 Jan 1 ;21(1):294-8. Epub 2010 Nov 5. PMID: 21123068 Abstract Title:  Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata. Abstract:  The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine influenza (novel influenza), represents a serious threat to global human health. …

Withania somnifera extract enhances energy expenditure via improving mitochondrial function in adipose tissue and skeletal muscle.

PMID:  Nutrients. 2020 Feb 7 ;12(2). Epub 2020 Feb 7. PMID: 32046183 Abstract Title:  Extract Enhances Energy Expenditure via Improving Mitochondrial Function in Adipose Tissue and Skeletal Muscle. Abstract:  Withania somnifera (WS), commonly known as ashwagandha, possesses diverse biological functions. WS root has mainly been used as an herbal medicine to treat anxiety and was …

Licocalchone-C extracted from Glycyrrhiza glabra inhibits lipopolysaccharide-interferon-γ inflammation.

PMID:  Molecules. 2011 Jul 6 ;16(7):5720-34. Epub 2011 Jul 6. PMID: 21734629 Abstract Title:  Licocalchone-C extracted from Glycyrrhiza glabra inhibits lipopolysaccharide-interferon-γ inflammation by improving antioxidant conditions and regulating inducible nitric oxide synthase expression. Abstract:  The genus Glycyrrhiza consists of about 30 species, amoung these, G. glabra is the source of several phenolic compounds, known as …

Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin.

PMID:  J Microbiol Biotechnol. 2012 Jun ;22(6):800-5. PMID: 22573157 Abstract Title:  Antimicrobial activity of licochalcone E against Staphylococcus aureus and its impact on the production of staphylococcal alpha-toxin. Abstract:  Licochalcone E was firstly isolated from licorice root in 2005, which belongs to the retrochalcone family. Studies on the biological activities of licochalcone E were in …

Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.

PMID:  Cancer Prev Res (Phila). 2013 Jun ;6(6):603-13. Epub 2013 Apr 26. PMID: 23625311 Abstract Title:  Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model. Abstract:  We investigated whether licochalcone E (LicE), a phenolic constituent of licorice, inhibits mammary tumor growth and metastasis using animal and cell culture models. …

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