PMID: Trop Anim Health Prod. 2010 Dec ;42(8):1855-60. Epub 2010 Jul 10. PMID: 20623187 Abstract Title: Putative probiotic Lactobacillus spp. from porcine gastrointestinal tract inhibit transmissible gastroenteritis coronavirus and enteric bacterial pathogens. Abstract: A total of 310 bacterial strains isolated from the porcine gastrointestinal tract were tested for their activity against transmissible gastroenteritis (TGE) coronavirus …
Author Archives: Taylor Mercado
Forsythoside a inhibits the avian infectious bronchitis virus (coronavirus) in cell culture.
PMID: Phytother Res. 2011 Mar ;25(3):338-42. PMID: 20677175 Abstract Title: Forsythoside a inhibits the avian infectious bronchitis virus in cell culture. Abstract: Forsythoside A is a polyphenolic constituent of the fruits of Forsythia suspensa Vahl. which is widely used as an antiinflammatory agent in traditional Chinese medicine. In the present study, the effects of forsythoside …
Medicinal herbal extracts of Sophorae radix, Acanthopanacis cortex, Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro.
PMID: Antivir Ther. 2010 ;15(5):697-709. PMID: 20710051 Abstract Title: Medicinal herbal extracts of Sophorae radix, Acanthopanacis cortex, Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro. Abstract: BACKGROUND: Cimicifuga rhizome, Meliae cortex, Coptidis rhizome and Phellodendron cortex have been previously shown to exhibit anti-coronavirus activity. Here, an additional 19 traditional medicinal herbal extracts were …
Apigenin, luteolin, and quercetin display SARS-coronavirus inhibition.
PMID: Bioorg Med Chem. 2010 Nov 15 ;18(22):7940-7. Epub 2010 Sep 19. PMID: 20934345 Abstract Title: Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. Abstract: As part of our search for botanical sources of SARS-CoV 3CL(pro) inhibitors, we selected Torreya nucifera, which is traditionally used as a medicinal plant in Asia. The ethanol extract of …
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Ganoderma lucidum (reishi) inhibits SARS-coronavirus RNA-dependent RNA polymerase.
PMID: Hong Kong Med J. 2011 Feb ;17 Suppl 2:41-3. PMID: 21368336 Abstract Title: Immunomodulatory activities of the herbal formula Kwan Du Bu Fei Dang in healthy subjects: a randomised, double-blind, placebo-controlled study. Abstract: [n/a] read more
This study found that Houttuynia cordata had more than 90% inhibition rate against avian infectious bronchitis virus (coronavirus) infection in Vero cells and chicken embryo kidney cells, and decreased more than 90% apoptotic cells caused by IBV.
PMID: Avian Pathol. 2011 Oct ;40(5):491-8. Epub 2011 Aug 18. PMID: 21848486 Abstract Title: In vitro and in vivo effects of Houttuynia cordata on infectious bronchitis virus. Abstract: Avian infectious bronchitis virus (IBV), a coronavirus, causes infectious bronchitis leading to enormous economic loss in the poultry industry worldwide. Houttuynia cordata (Saururaceae) (HC) is a traditional …
Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species.
PMID: Virol J. 2011 Oct 4 ;8:460. Epub 2011 Oct 4. PMID: 21967756 Abstract Title: Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species. Abstract: BACKGROUND: On the base of our previous study we were observed relevant studies on the hypothesis that the antiviral activity of quercetin …
7-O-arylmethylquercetin displays antiviral activity against SARS-coronavirus and hepatitis C virus.
PMID: Arch Pharm Res. 2012 Jan ;35(1):77-85. Epub 2012 Feb 2. PMID: 22297745 Abstract Title: Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV). Abstract: Aryl diketoacid (ADK) is well known for antiviral activity which can be enhanced by introduction of an aromatic arylmethyl substituent. A natural flavonoid …
Quercetin, EGCG, and CCG flavonoids inhibit SARS-coronavirus.
PMID: Biotechnol Lett. 2012 May ;34(5):831-8. Epub 2012 Feb 15. PMID: 22350287 Abstract Title: Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris. Abstract: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome associated coronavirus (SARS-CoV) is vital for SARS-CoV replication and is a promising drug target. Recombinant 3CL(pro) was expressed in Pichia …
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Tanshinones from red sage are strong inhibitors of SARS-coronavirus infection and replication.
PMID: Bioorg Med Chem. 2012 Oct 1 ;20(19):5928-35. Epub 2012 Aug 2. PMID: 22884354 Abstract Title: Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases. Abstract: In the search for anti-SARS-CoV, tanshinones derived from Salvia miltiorrhiza were found to be specific and selective inhibitors for the SARS-CoV 3CL(pro) and PL(pro), viral cysteine proteases. A …
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